Use of mycelial waste from the drug industry

It was shown that mycelial waste (MW) from manufacture of riboxin and neomycin was useful as an active filler for press compositions and a raw material for fuels. Addition of MW to a polymer press composition, depending on the amount added, provided a 2-10-fold decrease in the time of gel formation in the mixture and hardening of the products as well as a significant decrease in their shrinkage during the hardening. Optimal physicomechanical properties were achieved when the contents of MW and polymer in the press composition were equal. Pyrolysis of dry MW at a temperature of 450-500 degrees C resulted in formation of a product which was not inferior to the known fuels in its physicochemical properties. The low freezing point of the prepared fuel as compared to that of oil fuels allowed one to recommend it as a low-temperature additive to the fuels lowering their freezing points.     

Analysis of the kinetics of cell transition to DNA synthesis in systems with stimulated proliferation. I. Properties of a mathematical model of cell kinetics]

Some features of the mathematical model of cell kinetics in the systems stimulated or induced to proliferate are under consideration in this work. The proposed model serves as a basis of the kinetics analysis of the transition of cells to the DNA synthesis.     

Deviations from hyperbolic kinetics in slowly dissociating allosteric enzyme systems]

The feautres of kinetic behavior of dissociating enzyme systems for which the rate of equilibrium between the oligomeric forms is slow in comparison with the rate of the enzymatic process are discussed. It is shown that in slowly dissociating enzyme system of the type Np in equilibrium P (P is the enzyme oligomer, and p is the subunit: N greater than or equal to2) in which P and p forms differ by the character of allosteric interaction between the active and allosteric sites the plots of the initial reaction rate (v) versus substrate (S) or effector (F) concentration may be a very complicated shape. In similar systems the v versus [S]0 plots may have intermediate plateau, maximum and minimum simultaneously, sigmoidality followed by intermediate plateau and so on, and the v versus [F]0 plots may have intermediate plateau.