Disease management.

The disease management approach to patient care seeks to coordinate resources across the healthcare delivery system. The growing interest in evidence based medicine and outcomes, and a commitment to integrated care across the primary, secondary, and community care sectors, all contribute to making disease management an attractive idea. A combination of patient education, provider use of practice guidelines, appropriate consultation, and supplies of drugs and ancillary services all come together in the disease management process. But its effectiveness is largely untested, so evaluation is essential.     

Anomals and anopes among Beduin of Southern Sinai

Anomaloscope tests on 212 Beduin of Sinai revealed one extreme protanomal, one simple deuteranomal, five protanopes and three deuteranopes. Thus mild defects in color vision are more rare than among Europeans, but severe colorblindness is just as frequent. It is difficult to fit these data to the hypothesis of relaxed selection.     

Disproportionate sexual dimorphism in the human face

Analysis of facial dimensions of 86 young adults and their 76 parents indicates that a disproportionate sexual dimorphism exists in the ramus of the mandible, demonstrating a regional difference in growth response. The male ramus is on the average 14% longer than the female ramus, whereas other facial dimensions approximate an 8% sex difference. The findings have relevance to the analysis of skeletal remains and suggest the desirability of age specific discriminant function analysis for the sexing of adult mandibles.     

Comparison of 16S rRNA sequences from the family Pasteurellaceae: phylogenetic relatedness by cluster analysis

The taxonomy of the family Pasteurellaceae has remained controversial despite investigations of biochemistry, serology, and nucleic acid relatedness. In an attempt to resolve some of this confusion, we have partially sequenced the 16S rRNAs of seven members of the family, representing all three genera. The sequences were aligned, similarity scores calculated, and single, average and complete linkage cluster analysis of the resulting distance matrix performed. In this way, an evolutionary branching pattern of these closely related species was reconstructed, and the approximate phylogenetic position of the family determined. Actinobacillus (Haemophilus) actinomycetemcomitans clustered with Haemophilus instead of Actinobacillus, supporting transfer of this species to the genus Haemophilus. Thus cluster analysis of phylogenetic relatedness was found to be particularly useful for studying closely related organisms, and could be performed using a microcomputer.