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211.
Rongjia Mao Jing Chen Yuejun Chen Zhigang Guo 《Physiology and Molecular Biology of Plants》2018,24(5):715-727
212.
To meet human needs, the geographical location of lead changes during the process of mining lead ore to produce lead products for use by humans. These changes reveal the influence of human activities on lead distribution on the surface of Earth. In this study, a framework was built to analyze changes in lead distribution. Lead was traced through its life cycle using this framework. The provincial administrative unit in mainland of China was defined as the unit of space. The process of anthropogenic spatial transfer of lead was quantitatively analyzed by comparing lead distribution between different areas during each stage of its life cycle in 2010. The results showed that in 2010, around 60% of domestic lead resources were distributed in the Inner Mongolia Autonomous Region, Yunnan Province, and other locations in China. Nearly 80% of the refined lead was produced in Henan, Anhui, Hunan, Yunnan, and Jiangsu provinces. More than 50% of lead products were fabricated and manufactured in Zhejiang, Jiangsu, Shandong, and Hebei provinces. The distribution of lead usage and scrap recovery was relatively uniform (approximately 21 provinces accounted for 1% to 6% of all scrap in the country), although lead products and scrap were mainly distributed in Guangdong, Shandong, Jiangsu, and Zhejiang provinces, which together accounted for nearly 40% of the total. The recycling of lead scrap was mainly concentrated in Anhui (around 57% of the total). Overall, during the whole process, from the mining lead ore from the lithosphere to each stage of the product life cycle, lead was gradually transferred from the south and north of China to the central area and, finally, to the eastern coastal areas. 相似文献
213.
Binhao Zhang Bixiang Zhang Zhiwei Zhang Zhiyong Huang Yifa Chen Minshan Chen Ping Bie Baogang Peng Liqun Wu Zhiming Wang Bo Li Jia Fan Lunxiu Qin Ping Chen Jingfeng Liu Zhe Tang Jun Niu Xinmin Yin Deyu Li Songqing He Bin Jiang Yilei Mao Weiping Zhou Xiaoping Chen 《中国科学:生命科学英文版》2018,(6)
Hepatectomy is currently routinely performed in most hospitals in China. China owns the largest population of liver diseases and the biggest number of liver resection cases. A nationwide multicenter retrospective investigation involving 112 hospitals was performed, and focused on liver resection for patients with hepatocellular carcinoma(HCC). 42,573 cases of hepatectomy were enrolled, and 18,275 valid cases of liver resection for HCC patients were selected for statistical analysis. The epidemiology of HCC, distribution of hepatectomy, postoperative complications and prognosis were finally analyzed. In the 18,275 HCC patients,81% had hepatitis B virus infection and 10% had hepatitis C virus infection. 38% of the HCC patients had normal Alphafetoprotein(AFP) level, and other 35% had an AFP level lower than 400 ng mL~(-1). In the study period, 97% of the hepatectomy for HCC were treated with open surgery, and 23.81% had vascular exclusion techniques. The operation time was(191.7±105.6) min,the blood loss was(546.0±562.8) m L, and blood transfusion was(543.0±1,035.2) m L. The median survival for HCC patients was 631 days, with 1-, 3-, and 5-year overall survival of 73.2%, 28.8% and 19.6%, respectively. Liver cirrhosis, multiple nodules,tumor thrombosis and high AFP level were risk factors that affect postoperative survival. 相似文献
214.
215.
Xu M Zhou Z Cheng C Zhao W Tang R Huang Y Wang W Xu J Zeng L Xie Y Mao Y 《The international journal of biochemistry & cell biology》2001,33(12):1172-1182
Tektins comprise a family of filament-forming proteins that are known to be coassembled with tubulins to form ciliary and flagellar microtubules. A new member of the tektin gene family was cloned from the human fetal brain cDNA library. We hence named it the human TEKTIN1 gene. TEKTIN1 cDNA consists of 1375 bp and has a putative open reading frame encoding 418 amino acids. The predicted protein is 48.3 kDa in size, and its amino acid sequence is 82% identical to that of the mouse, rat, and dog. One conserved peptide RPNVELCRD was observed at position number 323–331 of the amino acid sequence, which is a prominent feature of tektins and is likely to represent a functionally important protein domain. TEKTIN1 gene was mapped to the human chromosome 17 by BLAST search, and at least eight exons were found. Northern blot analysis indicated that TEKTIN1 was predominantly expressed in testis. By in-situ hybridization analysis, TEKTIN1 mRNA was localized to spermatocytes and round spermatids in the seminiferous tubules of the mouse testis, indicating that it may play a role in spermatogenesis. 相似文献
216.
Chang-Juan Tao Li Lin Guan-Qun Zhou Ling-Long Tang Lei Chen Yan-Ping Mao Mu-Sheng Zeng Tie-Bang Kang Wei-Hua Jia Jian-Yong Shao Hai-Qiang Mai Ai-Hua Lin Jun Ma Ying Sun 《PloS one》2014,9(10)
Background
We aimed to compare the long-term survival outcomes and acute toxicity of cisplatin administered weekly versus every three weeks concurrently with intensity-modulated radiotherapy (IMRT) in patients with nasopharyngeal carcinoma (NPC).Methods
This was a retrospective review of 154 patients with histologically proven, non-disseminated NPC who were treated using IMRT between January 2003 and December 2007. Seventy-three patients (47.4%) received 5–7 weeks of 30–40 mg/m2 cisplatin weekly; 81 patients (52.6%) received two or three cycles of 80 mg/m2 cisplatin every three weeks. IMRT was delivered at 68 Gy/30 fractions to the nasopharyngeal gross target volume and 60–66 Gy to the involved neck area.Results
The clinical characteristics and treatment factors of the two groups were well-balanced. The median follow-up was 74 months (range, 6–123 months), and the 5-year overall survival, disease-free survival, locoregional relapse-free survival, and distant metastasis–free survival rates were 85.2% vs. 78.9% (P = 0.318), 71.6% vs. 71.0% (P = 0.847), 93.5% vs. 92.6% (P = 0.904), and 80.9% vs. 80.1% (P = 0.925) for the group treated every three weeks and weekly, respectively. Subgroup analyses indicated no significant differences in the survival rates of the two groups among patients with early- or advanced-stage disease. The incidence of acute toxicities was similar between groups.Conclusion
IMRT with concurrent cisplatin administered weekly or every three weeks leads to similar long-term survival outcomes and acute toxicity in NPC regardless of whether patients have early- or advanced-stage disease. 相似文献217.
Zhang CL Wang GP Mao LJ Komon-Zelazowska M Yuan ZL Lin FC Druzhinina IS Kubicek CP 《Fungal biology》2010,114(10):797-808
The fungal genus Muscodor was erected on the basis of Muscodor albus, an endophytic fungus originally isolated from Cinnamomum zeylanicum. It produces a mixture of volatile organic compounds (VOCs) with antimicrobial activity that can be used as mycofumigants. The genus currently comprises five species. Here we describe the isolation and characterization of a new species of Muscodor on the basis of five endophytic fungal strains from leaves of Actinidia chinensis, Pseudotaxus chienii and an unidentified broad leaf tree in the Fengyangshan Nature Reserve, Zhejiang Province, Southeast of China. They exhibit white colonies on potato dextrose agar (PDA) media, rope-like mycelial strands, but did not sporulate. The optimum growth temperature is 25°C. The results of a phylogenetic analysis based on four loci (ITS1-5.8S-ITS2, 28S rRNA, rpb2 and tub1) are consistent with the hypothesis that these five strains belong to a single taxon. All five strains also produce volatile chemical components with antimicrobial activity in vitro, which were different from those previously described for other Muscodor species. 相似文献
218.
382 yak cows were examined for milk yield, fat, protein and lactose contents. Six polymorphic loci, alphas1-CN, kappa-CN, beta-CN, beta-Lg, alpha-La and MUC-1, were scored by PAGE electrophoresis for each individual. The values of milk yield, fat, protein and lactose content were 247.13 kg, 5.81%, 5.18% and 4.93%, respectively. Based on the 6 polymorphism loci, the average heterozygosity of the yak population was 0.1794. Calculated by the marker-based method, heritability estimates for milk yield, fat, protein and lactose contents were 0.353 +/- 0.093, 0.316 +/- 0.101, 0.415 +/- 0.098 and 0.481 +/- 0.035, respectively. The relatively high or medium heritability of these traits indicate that it is feasible to rely directly on them in breeding for the improvement in a relatively short period. The significant linear regression between heterozygosity and fat percentage with a positive slope (R = 0.0420) indicated that inbreeding affected milk fat content in this population. 相似文献
219.
Natural wild-type strains of Bacillus subtilis spore is regarded as a non-pathogenic for both human and animal, and has been classified as a novel food which is currently
being used as probiotics added in the consumption. To identify B. subtilis spore proteins, we have accomplished a preliminary proteomic analysis of B. subtilis spore, with a combination of two-dimensional electrophoretic separations and matrix-assisted laser desorption ionization
tandem time of flight mass spectrometry (MALDI–TOF–MS). In this article, we presented a reference map of 158 B. subtilis spore proteins with an isoelectric point (pI) between 4 and 7. Followed by mass spectrometry (MS) analysis, we identified
71 B. subtilis spore proteins with high level of confidence. Database searches, combined with hydropathy analysis and GO analysis revealed
that most of the B. subtilis spore proteins were hydrophilic proteins related to catalytic function. These results should accelerate efforts to understand
the resistance of spore to harsh conditions. 相似文献
220.