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721.
722.
Gillian Hodge 《Arts Education Policy Review》2013,114(4):35-38
Abstract Revisiting Music Education Research Richard Colwell and Carol Richardson, eds. The New Handbook of Research on Music Teaching and Learning New York: Oxford University Press 1222 pp. $175.00 A Thing of Beauty Is a Joy Forever? David Kenneth Holt The Search for Aesthetic Meaning in the Visual Arts: The Need for the Aesthetic Tradition in Contemporary Art Theory and Education Bergin &; Garvey Publishers 148 pp. $62.50 相似文献
723.
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725.
The molecular organization of the beta-globin complex of the deer mouse, Peromyscus maniculatus 总被引:1,自引:0,他引:1
Padgett RW; Loeb DD; Snyder LR; Edgell MH; Hutchison CA d 《Molecular biology and evolution》1987,4(1):30-45
Recombinant DNA clones have been isolated that contain 80 kb of the
beta-globin complex from the deer mouse, Peromyscus maniculatus.
Comparisons of this complex with that from the laboratory mouse, Mus
domesticus (with an order 5'-Hbby, Hbb-bhO, Hbb-bhl, Hbb-bh2, Hbb-bh3,
Hbb-bl, Hbb-b2 3') highlight organizational trends in the beta-globin
complex since the two species diverged. Unlike other mammals studied thus
far, the deer mouse possesses three adult genes. Partial sequence analysis
indicates that each of the three adult genes is intact and hence may be
functional. Hybridization of one of the two Mus pseudogenes, Hbb-bh3, to
genomic blots from Peromyscus reveals that it has a homologous counterpart
in Peromyscus. Homologous genes to the two gamma-like Mus genes, Hbb-bhO
and Hbb-bhl, are also found in Peromyscus. The strong hybridization between
the Hbb-bhl genes and significant nucleotide similarity between the Hbb-bhO
genes suggest that both pairs are important for the ontogeny of these mice
although no known product has been identified for the Hbb-bhO genes. The
presence of Hbb-bhO and Hbb-bhl in Peromyscus suggests that the duplication
that created this related gene set occurred before the two lineages
diverged. A single gene for Hbb-y has been isolated from Peromyscus. The
adult region in Peromyscus has undergone significant divergence from the
same region in Mus, having three rather than two adult genes, the
acquisition of at least 15 kb of extra DNA relative to Mus, and possibly
the loss of the Hbb-bh2 pseudogene. The nonadult region of the complex, in
contrast, contains the same set of genes apparently distributed over the
same amount of DNA as in the Mus beta- globin complex. This observation
suggests that the embryonic region of the complex is more evolutionarily
stable than the adult region.
相似文献
726.
727.
Rat and human adrenal gland preparations were incubated with radioactive cholesterol and 23,24-dinor-5-cholen-3 beta-ol, the latter being a proposed intermediate in the sesterterpene pathway for steroid biosynthesis. Steroids were isolated, purified by TLC and crystallised to constant specific activity. It was found that rat and human adrenal glands can utilise 23,24-dinor-5-cholen-3 beta-ol to produce androstenedione and dehydroepiandrosterone. Also, it was found that the conversion of 23,24-dinor-5-cholen-3 beta-ol to androgens occurs in the microsomal fraction. It was concluded that the sesterterpene pathway for steroid biosynthesis can function in the rat and human adrenal glands to produce androgens and that the intermediates are converted to androgens in the microsomal fraction. 相似文献
728.
Allison M. Hodge Gary K. Dowse Paul Z. Zimmet Veronica R. Collins 《Obesity (Silver Spring, Md.)》1995,3(Z2):77s-88s
Surveys conducted in 10 Pacific island populations and in the multiethnic populations of Mauritius and Rodrigues in the Indian Ocean have provided data on the prevalence of obesity, potential etiological factors and medical hazards associated with obesity. The results indicate that the prevalence of obesity (by body mass index (BMI)) in some of these populations is among the highest in the world. Obesity related to degree of modernization is more common in urban than in rural locations and tends to be found more often in women. In two populations where longitudinal data were available, there were dramatic increases in prevalence over relatively short time periods. Obesity contributed to the risk of non-insulin-dependent diabetes mellitus (NIDDM) and was associated with other risk factors for cardiovascular disease (CVD) in all populations, but no relationship could be found with total mortality in three ethnic groups for whom data were available. A genetic susceptibility to obesity combined with social pressures that favor high energy intakes and reduced physical activity are believed to be important in these populations. The challenge for the future lies in developing culturally appropriate programs for preventing obesity and thus reducing associated morbidity, while continuing to research its behavioral and genetic determinants. 相似文献