全文获取类型
收费全文 | 302篇 |
免费 | 24篇 |
专业分类
326篇 |
出版年
2022年 | 2篇 |
2018年 | 4篇 |
2016年 | 4篇 |
2015年 | 8篇 |
2014年 | 8篇 |
2013年 | 8篇 |
2012年 | 12篇 |
2011年 | 13篇 |
2010年 | 6篇 |
2009年 | 8篇 |
2008年 | 19篇 |
2007年 | 17篇 |
2006年 | 14篇 |
2005年 | 21篇 |
2004年 | 15篇 |
2003年 | 13篇 |
2002年 | 14篇 |
2001年 | 12篇 |
2000年 | 14篇 |
1999年 | 10篇 |
1998年 | 1篇 |
1997年 | 1篇 |
1996年 | 3篇 |
1995年 | 2篇 |
1993年 | 4篇 |
1992年 | 9篇 |
1991年 | 12篇 |
1990年 | 13篇 |
1989年 | 9篇 |
1988年 | 9篇 |
1987年 | 4篇 |
1986年 | 5篇 |
1985年 | 3篇 |
1983年 | 5篇 |
1982年 | 4篇 |
1981年 | 7篇 |
1980年 | 1篇 |
1978年 | 5篇 |
1977年 | 3篇 |
1976年 | 1篇 |
1975年 | 2篇 |
1972年 | 1篇 |
排序方式: 共有326条查询结果,搜索用时 0 毫秒
321.
Clonotypes of anti-DNA antibodies expressing specific idiotypes in immune complexes of patients with active lupus nephritis 总被引:5,自引:0,他引:5
T Muryoi T Sasaki A Hatakeyama S Shibata M Suzuki J Seino K Yoshinaga 《Journal of immunology (Baltimore, Md. : 1950)》1990,144(10):3856-3861
IEF, using 6 M urea, provides a unique opportunity to analyze the spectrotypes of antibodies in immune complexes (IC) in vivo. Using this technique, we have analyzed the clonotypes of anti-DNA antibodies expressing specific Id in the circulating IC of patients with active lupus nephritis. Serum anti-ssDNA and anti-dsDNA antibodies showed heterogeneous spectrotypes. The antibodies isolated from circulating IC had a restricted clonotype and a neutral charge and were directed mainly to ssDNA and, to a lesser extent, to dsDNA. These samples failed to form complexes with DNA when they were subjected to absorption to a DNA-coupled Sepharose column. Anti-DNA antibodies expressed specific Id, termed O-81 or NE-1, which were detected only in the IC of patients with active lupus nephritis. Anti-DNA clonotypes, including O-81 and NE-1 idiotypes, were also found in the eluates of renal glomeruli of lupus patients. These results indicate that subpopulations of anti-DNA antibodies in circulating IC are limited, and may play an important role in the pathogenesis of lupus nephritis. 相似文献
322.
323.
S Seino Y Seino H Sakurai J Takemura H Kuzuya H Imura K Ishikawa T Shimazu M Usami M Ikeda 《Life sciences》1981,28(20):2231-2236
The effect of electrolytic lesions in the ventromedial hypothalamic nuclei (VMH) on somatostatin and insulin release was studied using the isolated perfused rat pancreas. Obesity gradually developed in the rats after placement of the VMH lesions, and fasting insulin levels determined immediately before the isolation of the pancreas were significantly higher than those in sham-operated controls. In the presence of 4.4 mM glucose, both perfusate somatostatin and insulin responses to arginine were significantly greater than in the controls, suggesting that VMH lesions cause not only hypersecretion of insulin but hypersecretion of somatostatin as well. 相似文献
324.
325.
Promoting effect of wood vinegar compounds on fruit-body formation ofPleurotus ostreatus 总被引:3,自引:0,他引:3
Hisashi Yoshimura Hisako Washio Sadao Yoshida Takao Seino Mitsuho Otaka Kazunori Matsubara Matsutoshi Matsubara 《Mycoscience》1995,36(2):173-177
The promoting effect of wood vinegar compounds on the fruiting ofPleurotus ostreatus (Japanese name, Hiratake) was investigated. Not only crude wood vinegar but its components, 3,5-dimethylphenol, 2-methoxyphenol, butanoic acid and 1-pentanol, had the ability to promote fruit-body formation on liquid medium. For use of these promoters industrially, a test for practical cultivation was carried out using a commercial sawdust medium. The addition of 100 µg/ml butanoic acid and 100 µg/ml 2-methoxyphenol into the sawdust medium after removal of the surface mycelial layer (kinkaki in Japanese) produced 29 and 23% higher yields of fruit-bodies than the control cultures (137.2 g/bottle), respectively. The addition of the crude wood vinegar as a medium component into sawdust substrates in the concentration range of 0.1–6% increased yields of fruit-bodies by 21–42% over the control. 相似文献
326.