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231.
232.
Takeshi Minami Masayo Ichii Jiro Okazaki Hideko Kawaki Yuko Okazaki 《Biological trace element research》1996,55(1-2):1-7
We investigated whether free radical scavengers and antioxidants inhibit the accumulation of platinum (Pt) in the cerebral
cortex. Pt was detected in the cerebral cortex of mice afters administration of cisplatin and exposure to short-term hypoxia.
When mice were treated with either allopurinol (20 mg/kg) or catalase (100 mg/kg) before cisplatin administration and low
oxygen exposure, Pt was not detected in the cerebral cortex. However, Pt was detected in the cerebral cortex of mice pretreated
with either a low dosage of allopurinol or heat-denatured catalase. Furthermore, Pt was detected in the cerebral cortex of
mice preadministered vitamin C, vitamin E, or deferoxamine. Lipid peroxide levels in the cerebral cortex increased 10 min
after the treatment of hypoxia, and peaked 30 min after the treatment. These results suggested that short-term hypoxia produces
free radicals, which allows Pt to pass through the blood-brain barrier and accumulate in the cerebral cortex, and that the
production of free radicals is reduced by the administration of either allopurinol or catalase, which prevents Pt from passing
through the barrier. 相似文献
233.
234.
Tasuku Sugimoto Hiromi Kobayashi Noritomo Nobuyoshi Yasushi Kiriyama Hideko Takeshita Tomoyasu Nakamura Kazuhide Hashiya 《Primates; journal of primatology》2010,51(1):7-12
It has been shown that humans prefer consonant sounds from the early stages of development. From a comparative psychological
perspective, although previous studies have shown that birds and monkeys can discriminate between consonant and dissonant
sounds, it remains unclear whether nonhumans have a spontaneous preference for consonant music over dissonant music as humans
do. We report here that a five-month-old human-raised chimpanzee (Pan troglodytes) preferred consonant music. The infant chimpanzee consistently preferred to produce, with the aid of our computerized setup,
consonant versions of music for a longer duration than dissonant versions. This result suggests that the preference for consonance
is not unique to humans. Further, it supports the hypothesis that one major basis of musical appreciation has some evolutionary
origins. 相似文献