全文获取类型
收费全文 | 751篇 |
免费 | 84篇 |
国内免费 | 1篇 |
出版年
2021年 | 16篇 |
2020年 | 9篇 |
2019年 | 8篇 |
2018年 | 12篇 |
2017年 | 7篇 |
2016年 | 14篇 |
2015年 | 18篇 |
2014年 | 29篇 |
2013年 | 45篇 |
2012年 | 43篇 |
2011年 | 45篇 |
2010年 | 32篇 |
2009年 | 25篇 |
2008年 | 38篇 |
2007年 | 38篇 |
2006年 | 33篇 |
2005年 | 40篇 |
2004年 | 21篇 |
2003年 | 29篇 |
2002年 | 25篇 |
2001年 | 23篇 |
2000年 | 25篇 |
1999年 | 24篇 |
1998年 | 12篇 |
1997年 | 25篇 |
1996年 | 15篇 |
1995年 | 16篇 |
1994年 | 8篇 |
1993年 | 8篇 |
1992年 | 9篇 |
1991年 | 6篇 |
1990年 | 14篇 |
1989年 | 5篇 |
1988年 | 7篇 |
1987年 | 9篇 |
1986年 | 7篇 |
1985年 | 8篇 |
1984年 | 5篇 |
1983年 | 7篇 |
1982年 | 3篇 |
1981年 | 6篇 |
1980年 | 4篇 |
1979年 | 12篇 |
1978年 | 4篇 |
1977年 | 3篇 |
1976年 | 9篇 |
1975年 | 6篇 |
1971年 | 4篇 |
1969年 | 4篇 |
1966年 | 4篇 |
排序方式: 共有836条查询结果,搜索用时 687 毫秒
831.
Maïlys Gauthier Bertrand Launay Guillaume Le Goff Herve Pella Christophe J. Douady Thibault Datry 《Freshwater Biology》2020,65(12):2169-2185
- Dispersal, defined as the movement of individuals among local communities in a landscape, is a central regional determinant of metacommunity dynamics in ecosystems. Whereas both natural and anthropogenic ecosystem fragmentations can limit dispersal, previous attempts to measure such limitations have faced considerable context dependency, due to a combination of spatial extent and associated environmental variability, the wide range of dispersal modes, and abilities of organisms or variation in network topologies. Therefore, the role dispersal plays compared to local environmental filtering in explaining metacommunity dynamics remains unclear in fragmented dendritic ecosystems.
- We quantified α- and β-diversity components of invertebrate metacommunities across 10 fragmented headwater stream networks and tested the hypothesis that dispersal is the primary determinant of biodiversity organisation in these dynamic and spatially constrained ecosystems.
- Alpha-diversity was much lower in intermittent than perennial reaches, even long after rewetting, indicating an overwhelming effect of drying including a legacy effect on local communities.
- Beta-diversity was never correlated with environmental distances but predominantly explained by spatial distances accounting for river network fragmentation. The nestedness proportion of β-diversity was considerable and reflected compositional differences where communities from intermittent reaches were subsets of perennial reaches.
- Altogether, these results indicate dispersal as the primary process shaping metacommunity dynamics in these 10 headwater stream networks, where local communities recurrently undergo extinction and recolonisation events. This challenges previous conceptual views that local environment filtering is the main driver of headwater stream metacommunities.
- As river networks become increasingly fragmented due to global change, our results suggest that some freshwater ecosystems currently driven by local environment filtering could gradually become dispersal-limited. In this perspective, shifts from perennial to intermittent flow regimes represent ecological thresholds that should not be crossed to avoid jeopardising river biodiversity, functional integrity, and the ecosystem services they provide to society.
832.
833.
Herve Goudonnet Jacques Magdalou Jacques Mounie Abderrahim Naoumi Marie-Laure Viriot Andre Escousse Gerard Siest Roger Truchot 《Biochimica et Biophysica Acta (BBA)/General Subjects》1990,1035(1):12-19
The effect of thyroid hormones and chemically related compounds, on the activity of UDP-glucuronosyltransferases (EC 2.4.1.17) and cytochrome P-450-dependent monooxygenases in rat liver microsomes was investigated. The animals were thyroidectomized and treated with different doses of the drugs for 3 weeks. Opposite effects were observed depending on the isoenzyme of UDP-glucuronosyltransferase considered. While 3,3′,5-triiodo-l-thyronine, 3,3′,5-triiodothyroacetic acid, 3,3′,5-triiodothyropropionic acid, isopropyldiiodothyronine and l- and d-thryoxine strongly increased 4-nitrophenol glucuronidation in a dose-dependent fashion, they decreased markedly bilirubin glucuronidation. However, the activity toward nopol, a monoterpenoid alcohol, was not significantly changed regardless of which compound or dose was used. Variation of UDP-glucuronosyltransferase observed with 4-nitrophenol and bilirubin was related to the thyromimetic effect of the drugs estimated from the increase in α-glycerophosphate dehydrogenase. Thyronine and 3,5-diiodo-l-tyrosine, which did not enhance this activity, also failed to affect glucuronidation. Variations in UDP-glucuronosyltransferase activity were more likely due to changes in protein expression rather than changes in enzyme latency, since lipid organization of the microsomal membrane, as estimated from the mean anisotropy of 1,6-diphenyl-1,3,5-hexatriene by fluorescence polarization was not significantly modified by the drug administration. Although some of the drugs could significantly decrease the triacylglycerol and cholesterol contents in plasma, all failed to affect lauric acid hydroxylation. The activities of catalase, palmitoyl-CoA dehydrogenase (CN? insensitive) and carnitine acetyltransferase in the fraction enriched in peroxisomes were also not significantly affected by treatment with the thyroid hormone LT3. In contrast, the activity of 7-ethoxycoumarine O-deethylase was increased by large doses of thyronine and by 3,3′,5′-triiodothyropropionic acid. The concentration of total cytochrome P-450 was decreased in a dose-dependent fashion by all the compounds used, except thyronine. Finally, significant correlations were observed between glucuronidation of bilirubin and 4-nitrophenol and the content in cytochrome P-450. This suggests a possible coordinate regulation of the two processes, which depends on the physicochemical characteristics of the thyroid hormones and related compounds. 相似文献
834.
Applied to 135 Acanthodactylus, from eight clusters of collecting sites, a multidimensional analysis of 11 characters, mainly of colouring and scale patterns, providing 35 mathematical variables, reveals a hight intrapopulational variability. Samples dwelling on reg nebkhas and sandy knolls in the river beds are Acanthodactylus inornatus. Some specimens, in the sample from barkhanes and sand dunes areas, are morphologically close to A. longipes. 相似文献
835.
Effects of space environment on embryonic growth up to hatching of salamander eggs fertilized and developed during orbital flights. 总被引:1,自引:0,他引:1
Lydie Gualandris-Parisot David Husson Alain Bautz Danielle Durand Paulette Kan Christian Aimar Herve Membre Anne-Marie Duprat Christian Dournon 《Biological Sciences in Space》2002,16(1):3-11
In vertebrates, only few experiments have been performed in microgravity to study the embryonic development from fertilization. To date, these concern only amphibian and fish. We report here a study on the embryonic development of Pleurodeles waltl (urodele amphibian) eggs oviposited in microgravity. The experiment was performed twice on board the Mir space station and the data obtained included video recording and morphological, histological and immunocytological analyses. The data confirm that the microgravity conditions have effects during the embryonic period, particularly during cleavage and neurulation, inducing irregular segmentation and abnormal closure of the neural tube. Moreover, we observed several abnormalities hither to undescribed corresponding to cortical cytoplasm movements, a decrease of cell adhesion and a loss of cells. These abnormalities were temporary and subsequently reversible. The young larvae that hatched during the flight displayed normal morphology and swimming behavior after landing. The results obtained in the urodele Pleurodeles waltl are in accordance with those observed earlier in the anuran Xenopus laevis and in the fish Oryzias latipes. 相似文献
836.
A. L. Santerre I. Queinnec C. Destruhaut J. B. Pourciel P. J. Blanc 《Biotechnology Techniques》1994,8(5):319-324
Summary A novel method for evaluating pigment production during fermentation ofMonascus ruber has been developed and consists of reflectance measurement with a 10° observer under an artificial illuminant. A spectrophotometer
was adapted to measure pigmentation during culture in a bioreactor. The lightness parameter L was the most useful information
delivered by this sensor. An absorbency over 30 units at 480nm on batch cultures was estimated on-line without dilution.
member of the GR Automatique - SARTA - CNRS 相似文献