全文获取类型
收费全文 | 5916篇 |
免费 | 538篇 |
国内免费 | 7篇 |
出版年
2021年 | 56篇 |
2018年 | 47篇 |
2017年 | 41篇 |
2016年 | 96篇 |
2015年 | 156篇 |
2014年 | 168篇 |
2013年 | 238篇 |
2012年 | 282篇 |
2011年 | 273篇 |
2010年 | 184篇 |
2009年 | 196篇 |
2008年 | 274篇 |
2007年 | 261篇 |
2006年 | 294篇 |
2005年 | 257篇 |
2004年 | 217篇 |
2003年 | 240篇 |
2002年 | 237篇 |
2001年 | 86篇 |
2000年 | 105篇 |
1999年 | 105篇 |
1998年 | 79篇 |
1997年 | 68篇 |
1996年 | 65篇 |
1995年 | 50篇 |
1994年 | 57篇 |
1993年 | 53篇 |
1992年 | 67篇 |
1991年 | 67篇 |
1990年 | 72篇 |
1989年 | 56篇 |
1988年 | 41篇 |
1987年 | 54篇 |
1986年 | 53篇 |
1985年 | 59篇 |
1984年 | 82篇 |
1983年 | 69篇 |
1982年 | 66篇 |
1981年 | 70篇 |
1980年 | 59篇 |
1979年 | 67篇 |
1978年 | 70篇 |
1977年 | 54篇 |
1976年 | 63篇 |
1974年 | 45篇 |
1973年 | 57篇 |
1972年 | 50篇 |
1970年 | 41篇 |
1969年 | 51篇 |
1967年 | 45篇 |
排序方式: 共有6461条查询结果,搜索用时 15 毫秒
11.
Jens Blechert Eva Naumann Julian Schmitz Beate M. Herbert Brunna Tuschen-Caffier 《PloS one》2014,9(1)
Many individuals restrict their food intake to prevent weight gain. This restriction has both homeostatic and hedonic effects but their relative contribution is currently unclear. To isolate hedonic effects of food restriction, we exposed regular chocolate eaters to one week of chocolate deprivation but otherwise regular eating. Before and after this hedonic deprivation, participants viewed images of chocolate and images of high-calorie but non-chocolate containing foods, while experiential, behavioral and eyeblink startle responses were measured. Compared to satiety, hedonic deprivation triggered increased chocolate wanting, liking, and chocolate consumption but also feelings of frustration and startle potentiation during the intertrial intervals. Deprivation was further characterized by startle inhibition during both chocolate and food images relative to the intertrial intervals. Individuals who responded with frustration to the manipulation and those who scored high on a questionnaire of impulsivity showed more relative startle inhibition. The results reveal the profound effects of hedonic deprivation on experiential, behavioral and attentional/appetitive response systems and underscore the role of individual differences and state variables for startle modulation. Implications for dieting research and practice as well as for eating and weight disorders are discussed. 相似文献
12.
Roger Williams Herbert Axelrod Marie Greene Alexander McPherson 《Journal of Protein Chemistry》1987,6(4):343-352
The binding of pentaammineruthenium (III) to ribonuclease A and B both free and complexed with d(pA)4 has been examined in the crystalline state through the application of X-ray diffraction and difference Fourier techniques. In crystals of native RNase B, the reagent was observed to have many binding sites, some entirely electrostatic in nature and others consistent with coordination to histidine residues. The primary histidine in the latter case was 105 with 119 also partially substituted. In crystals of RNase A+d(pA)4 complex only a single, extremely strong site of substitution was observed, and this was 2.4 Å from the native position of the imidazole ring of histidine 105. Thus, the results of these X-ray diffraction studies appear to be quite consistent with the findings of earlier NMR studies and with the results obtained in crystals of the gene 5 DNA binding protein. 相似文献
13.
Posner , Herbert B., and William S. Hillman . (Yale U., New Haven, Conn.) Effects of x irradiation on Lemna perpusilla. Amer. Jour. Bot. 47(6): 506–511. Illus. 1960.—The effects of x rays on the multiplication rates (MR), percent flowering (Fl%) and gross morphology of aseptically grown cultures of Lemna perpusilla, strain 6746, were studied. MR values are unaffected by doses of less than 300 r but are progressively depressed as the dose increases. The effect of a given dose on short-term MR values is the same at the 2 dosage intensities used, 500 and 2000 r/min. The inhibitory effect of intermediate doses on long-term growth is delayed; high doses have an “immediate” effect. Bleaching of fronds and cessation of growth occur in all cultures given 5,000 r or higher. Radiosensitivity is not altered by addition of yeast extract and casein hydrolysate to the medium. Depressed Fl% and seed production appear to be consequences of lowered MR. Morphological aberrations such as small size, epinasty and wrinkling are temporary. Frond-sequence may be altered by x rays but this aberration is permanent. Various aspects of the results are discussed. 相似文献
14.
15.
16.
Role of different lymphoid tissues in the initiation and maintenance of DNA-raised antibody responses to the influenza virus H1 glycoprotein. 下载免费PDF全文
Antibody responses in mice immunized by a single gene gun inoculation of plasmid expressing the influenza virus H1 hemagglutinin and in mice immunized by a sublethal H1 influenza virus infection have been compared. Both immunizations raised long-lived serum responses that were associated with the localization of antibody-secreting cells (ASC) to the bone marrow. However, the kinetics of these responses were 4 to 8 weeks slower in the DNA-immunized than in the infection-primed mice. Following a gene gun booster, the presence of ASC in the inguinal lymph nodes, but not in other lymph nodes, revealed gene gun responses being initiated in the nodes that drain the skin target site. Both pre- and postchallenge, the DNA-immunized mice had 5- to 10-times-lower levels of antibody and ASC than the infection-primed mice. 相似文献
17.
18.
19.
20.