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81.
Vilizzi Lorenzo Copp Gordon H. Adamovich Boris Almeida David Chan Joleen Davison Phil I. Dembski Samuel Ekmekçi F. Güler Ferincz Árpád Forneck Sandra C. Hill Jeffrey E. Kim Jeong-Eun Koutsikos Nicholas Leuven Rob S. E. W. Luna Sergio A. Magalhães Filomena Marr Sean M. Mendoza Roberto Mourão Carlos F. Neal J. Wesley Onikura Norio Perdikaris Costas Piria Marina Poulet Nicolas Puntila Riikka Range Inês L. Simonović Predrag Ribeiro Filipe Tarkan Ali Serhan Troca Débora F. A. Vardakas Leonidas Verreycken Hugo Vintsek Lizaveta Weyl Olaf L. F. Yeo Darren C. J. Zeng Yiwen 《Reviews in Fish Biology and Fisheries》2019,29(3):529-568
Reviews in Fish Biology and Fisheries - The freshwater Fish Invasiveness Screening Kit (FISK) has been applied in 35 risk assessment areas in 45 countries across the six inhabited continents (11... 相似文献
82.
Xie M Kobayashi I Kiyoshima T Yamaza H Honda JY Takahashi K Enoki N Akamine A Sakai H 《The Journal of biological chemistry》2007,282(32):23275-23283
We examined the functional implication of nucleolin in the mouse first molar development. Both the nucleolin mRNA and protein expressions were demonstrated in the odontogenic epithelial cells in the early stage and in the inner enamel epithelial layer in the late stage. The expression pattern of nucleolin corresponded to the proliferating cells in the tooth germ, thus showing that nucleolin could possibly be related to cell proliferation. No in situ signal of nucleolin was found in the primary enamel knot (PEK). Furthermore, nucleolin protein was demonstrated in the PEK by immunohistochemistry. The existence of nucleolin protein in the PEK may possibly be related to the apoptosis in the PEK cells. An inhibition assay using the hemagglutinating virus of Japan-liposome containing nucleolin antisense phosphorothioated oligonucleotide (AS S-ODN) in cultured mouse mandibles at embryonic day (E) 11.0 showed a marked growth inhibition of tooth germ. Moreover, no developmental arrest was found in the cultured tooth germ at E15.0 treated with nucleolin AS S-ODN. Real time PCR was performed to examine the mRNA expression of nucleolin-related genes, and a significant reduction in the midkine mRNA expression was thus observed in the mouse mandible after being treated with nucleolin AS S-ODN. This inhibition assay indicated that nucleolin could thus be involved in the early stage of tooth germ initiation and morphogenesis, possibly by regulating the midkine expression. 相似文献
83.
Takeda N Maemura K Horie S Oishi K Imai Y Harada T Saito T Shiga T Amiya E Manabe I Ishida N Nagai R 《The Journal of biological chemistry》2007,282(45):32561-32567
Cardiovascular diseases are closely related to circadian rhythm, which is under the control of an internal biological clock mechanism. Although a biological clock exists not only in the hypothalamus but also in each peripheral tissue, the biological relevance of the peripheral clock remains to be elucidated. In this study we searched for clock-controlled genes in vascular endothelial cells using microarray technology. The expression of a total of 229 genes was up-regulated by CLOCK/BMAL2. Among the genes that we identified, we examined the thrombomodulin (TM) gene further, because TM is an integral membrane glycoprotein that is expressed primarily in vascular endothelial cells and plays a major role in the regulation of intravascular coagulation. TM mRNA and protein expression showed a clear circadian oscillation in the mouse lung and heart. Reporter analyses, gel shift assays, and chromatin immunoprecipitation analyses using the TM promoter revealed that a heterodimer of CLOCK and BMAL2 binds directly to the E-box of the TM promoter, resulting in TM promoter transactivation. Indeed, the oscillation of TM gene expression was abolished in clock mutant mice, suggesting that TM expression is regulated by the clock gene in vivo. Finally, the phase of circadian oscillation of TM mRNA expression was altered by temporal feeding restriction, suggesting TM gene expression is regulated by the peripheral clock system. In conclusion, these data suggest that the peripheral clock in vascular endothelial cells regulates TM gene expression and that the oscillation of TM expression may contribute to the circadian variation of cardiovascular events. 相似文献
84.
Norio Tanaka Yasushi Sasaki M. I. M. Mowjood K. B. S. N. Jinadasa Samang Homchuen 《Landscape and Ecological Engineering》2007,3(1):33-45
This study explored the effects of coastal vegetation on tsunami damage based on field observations carried out after the
Indian Ocean tsunami on 26 December 2004. Study locations covered about 250 km (19 locations) on the southern coast of Sri
Lanka and about 200 km (29 locations) on the Andaman coast of Thailand. The representative vegetation was classified into
six types according to their habitat and the stand structures of the trees. The impact of vegetation structure on drag forces
was analyzed using the observed characteristics of the tree species. The drag coefficient, including the vertical stand structures
of trees, C
d-all, and the vegetation thickness (cumulative trunk diameter of vegetation in the tsunami direction) per unit area, dN
u
(d: reference diameter of trees, N
u
: number of trees per unit area), varied greatly with the species classification. Based on the field survey and data analysis,
Rhizophora apiculata and Rhizophora mucronata (hereafter R. apiculata-type), kinds of mangroves, and Pandanus odoratissimus, a representative tree that grows in beach sand, were found to be especially effective in providing protection from tsunami
damage due to their complex aerial root structure. Two layers of vegetation in the vertical direction with P. odoratissimus and Casuarina equisetifolia and a horizontal vegetation structure of small and large diameter trees were also important for increasing drag and trapping
floating objects, broken branches, houses, and people. The vertical structure also provided an effective soft landing for
people washed up by the tsunami or for escaping when the tsunami waves hit, although its dN
u
is not large compared with R. apiculata-type and P. odoratissimus. In addition, the creeks inside mangroves and the gaps inside C. equisetifolia vegetation are assumed to be effective for retarding tsunami waves. This information should be considered in future coastal
landscape planning, rehabilitation, and coastal resource management. 相似文献
85.
Enoki N Kiyoshima T Sakai T Kobayashi I Takahashi K Terada Y Sakai H 《Journal of molecular histology》2007,38(4):321-332
This study investigated the age-dependent changes in the number of BrdU- and TUNEL-positive cells in murine gingival tissue
and submandibular gland, and compared the findings with those in other tissues and organs. The cell proliferative activity
was decreased after 20 weeks of age in epithelial cells of the gingiva, tongue, buccal mucosa and skin. A decreased cell proliferative
activity was also associated with aging in the liver and kidney parenchymal cells. Meanwhile, cell death showed peculiar changes
in gingival subepithelial tissue, and mucous and serous acini of the submandibular gland. An increase of TUNEL-positive cells
was demonstrated in gingival subepithelial tissue after 20-week-old of age. A significant increase of TUNEL-positive cells
was also found in the mucous acinar cells in the 20-week-old mice and in the serous acini after 20 weeks. The fluctuation
in the number of TUNEL-positive cells in the subepithelial tissue of the skin, and BrdU- and TUNEL-positive staining ratios
in the liver was smaller than that in other tissue and organs throughout life. This study may provide useful information for
better understanding the influence of aging on the functional alteration that occurs in the gingival tissue and submandibular
gland of the elderly. 相似文献
86.
Miyata Seiko Otake Hironao Fujishiro Hiroshige Iwamoto Kunihiro Noda Akiko Sone Michihiko Ozaki Norio 《Sleep and biological rhythms》2022,20(3):403-411
Sleep and Biological Rhythms - Sleep problems and obstructive sleep apnea (OSA) increase with age and disturb life in old age. Positional therapy is one option to treat OSA, but the differences in... 相似文献
87.
Seiko Miyata Sayumi Kawai Kumiko Honda Kunihiro Iwamoto Norio Ozaki 《Biological Rhythm Research》2019,50(2):171-179
Insufficient sleep and irregular sleep/wake rhythm are common problems among university students. We investigated the effect of sleep/wake rhythm and excessive daytime sleepiness (EDS) on the cortical oxygenation as measured by near-infrared spectroscopy (NIRS) and cognitive performance in university students. Peak- and integral values by a word fluency task were measured with NIRS. EDS was evaluated by the Epworth sleepiness scale (ESS), and performance function was evaluated using N-back task. Peak cerebral oxygenation was significantly correlated with ESS, bedtime, wake-up time, and median time of sleep. Accuracy on 2-back task was significantly correlated with integral value. Peak- and integral values were significantly lower, and bedtime and median time of sleep were significantly delayed in the EDS group than in the non-EDS group. EDS accompanied by delayed sleep/wake rhythm and short sleep duration may play an important role in decreasing daytime brain activity and cognitive performance. 相似文献
88.
Norio Ohashi Masahiro Fukuhara Masahiko Shimada Akira Tamura 《FEMS microbiology letters》1995,125(2-3):299-304
Abstract The 16S rRNA gene sequences of Rickettsia tsutsugamushi and Rickettsia sibirica were determined by PCR and DNA sequencing. Phylogenetic analysis revealed that R. sibirica is positioned in a cluster of the genus Rickettsia with a similarity value of 98.1–99.6%, whereas R. tsutsugamushi is located apart from the cluster with a similarity value of 90.2–90.6%. This evidence suggests that R. tsutsugamushi should be excluded taxonomically from the genus Rickettsia . The phylogenetic classification of six antigenic variants in R. tsutsugamushi moderately reflected their antigenic relationship known in closely and distantly related strains. 相似文献
89.
90.
The present paper describes a novel structure, termed the sperm-associated body, which is found both in the lumen at the oviductal infundibulum and in the vitelline membrane of the ovum in the quail Coturnix japonica. The fully developed sperm-associated body, which is about 100 microm long, consisted of two parts; a core of concentric-circular appearance and a cortex of needle-like projections. The outer surface of the body was coated with CaCO3. The body was always accompanied by spermatozoa. About 70 sperm-associated bodies were observed in a single ovum. Electron-microscopically, small numbers of holes were detected in the vitelline membranes of a fertile ovum, and the sperm-associated bodies were always present in these holes. Frequently observed in the vitelline membranes was a disk speculated to be a portion of the inner layer of the membrane partially affected by spermatozoa. However, neither sperm-associated bodies nor spermatozoa were observed there. It was suggested that the sperm-associated bodies assist fertile spermatozoa in binding the inner layer of the vitelline membrane and penetrating it. 相似文献