Interactions of sodium,calcium, and lanthanum ions with methyl glycofuranosides in methanol

The ¹³C-n.m.r. spectra have been recorded and assigned for the xylo- and cello-oligosaccharides, the former up to xylopentaose, and the latter up to cello-tetraose. A spectrum of a low-d.p. cellulose in dimethyl sulfoxide-d₆ was also assigned. In every instance, the spectra of the higher oligosaccharides closely parallel those of the corresponding disaccharides. Variations in line intensities permitted assignment of peaks to both terminal groups and internal residues. A particularly important difference was observed between the chemical shifts at the internal C-4 atoms for the two series of oligomers. This difference has been interpreted as evidence for significant differences in average linkage-orientation or solvation, which is related to the absence of C-6 in the xylo-oligosaccharides.     

Metabolic effects of repeated short-term exposures to heat in the rat

Repeated daily exposures of rats to a hot ambient temperature (40-41 degrees C) for 20 days induced activation of the oxidative enzymes in the thigh muscle and of lactate dehydrogenase in the myocardium. Heat-stressed rats also showed increased tolerance to cold. These changes, it is suggested, are caused by the increased sympathetic activity bouts associated with the heat stresses. The interscapular brown adipose tissue, however, showed adaptive changes similar to those induced by warm acclimation. The activity of oxidative enzymes was decreased and the fat droplets became large and unilocular.     

Physical training under the influence of beta blockade in rats: effect on adrenergic responses.

Rats were trained by daily swimming or running exercises with and without daily propranolol injections. Both training methods resulted in cardiac enlargement, but only swimming exercise caused hypertrophy of the brown adipose tissue. These changes were antagonized by beta blockade. The size of the adrenals reflected the stress of the treatments, but other known stress parameters, such as the size of the thymus or sexual organs dit not. Only swimming training without beta blockade sensitized the rats to the calorigenic action of noradrenaline. The cooling rate of the rats in water, when taking into account the insulative capacity of the body, was decreased in swimming-trained as well as in propranolol-treated rats but increased in running-trained rats. The latter two changes may be due to circulatory alterations, while the delayed body cooling in swimming-trained rats probably results from increased heat production capacity. Training-induced resting bradycardia and enhanced tachycardic response to isoprenaline were observable only in the animal groups trained without beta blockade. The pressor response to noradrenaline tended to be higher in the trained groups and the propranolol-treated group than in the controls and was smaller in the animal groups trained under the influence of beta blockade. On the other hand, the hypotonic response to isoprenaline was smaller in the propranolol-treated and running-trained animals. The results emphasize the importance of the sympathetic nervous system in the adaptation of an organism to physical training.     

Response to cold in the blue fox and raccoon dog as evaluated by metabolism, heart rate and muscular shivering: a re-evaluation

Oxygen consumption (ml kg-0.75/min) in relation to ambient air temperature at or below the lower critical temperature (Tlc) of the winter-furred raccoon dog (+10 degrees C) and the blue fox (-6 degrees C) is described by the equations y = 14.8-0.28x and y = 7.5-0.20x, respectively. Muscular shivering activity (integrated EMG) of both species increased below thermoneutrality parallel with increasing oxygen uptake and heart rate. Seasonal changes in measured metabolic parameters were evident for both species. The results suggest that the overall body insulation or the metabolic response to cold are not essentially worse in the raccoon dog as compared with the blue fox. It is concluded that earlier speculations of surprisingly wide thermoneutral zone and very low Tlc of the Arctic fox are not evident for the blue fox.