排序方式: 共有80条查询结果,搜索用时 15 毫秒
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Brambilla E Djao OD Daligault H Lapidus A Lucas S Hammon N Nolan M Tice H Cheng JF Han C Tapia R Goodwin L Pitluck S Liolios K Ivanova N Mavromatis K Mikhailova N Pati A Chen A Palaniappan K Land M Hauser L Chang YJ Jeffries CD Rohde M Spring S Sikorski J Göker M Woyke T Bristow J Eisen JA Markowitz V Hugenholtz P Kyrpides NC Klenk HP 《Standards in genomic sciences》2010,2(2):203-211
Segniliparus rotundus Butler 2005 is the type species of the genus Segniliparus, which is currently the only genus in the corynebacterial family Segniliparaceae. This family is of large interest because of a novel late-emerging genus-specific mycolate pattern. The type strain has been isolated from human sputum and is probably an opportunistic pathogen. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the first completed genome sequence of the family Segniliparaceae. The 3,157,527 bp long genome with its 3,081 protein-coding and 52 RNA genes is part of the Genomic Encyclopedia of Bacteria and Archaea project. 相似文献
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Shigeru Itoh Takashi Kozuki Koji Nishida Yoshimasa Fukushima Hisanori Yamakawa Ildikó Domonkos Hajnalka Laczkó-Dobos Mihály Kis Bettina Ughy Zoltán Gombos 《BBA》2012,1817(2):287-297
Functional roles of an anionic lipid phosphatidylglycerol (PG) were studied in pgsA-gene-inactivated and cdsA-gene-inactivated/phycobilisome-less mutant cells of a cyanobacterium Synechocystis sp. PCC 6803, which can grow only in PG-supplemented media. 1) A few days of PG depletion suppressed oxygen evolution of mutant cells supported by p-benzoquinone (BQ). The suppression was recovered slowly in a week after PG re-addition. Measurements of fluorescence yield indicated the enhanced sensitivity of QB to the inactivation by BQ. It is assumed that the loss of low-affinity PG (PGL) enhances the affinity for BQ that inactivates QB. 2) Oxygen evolution without BQ, supported by the endogenous electron acceptors, was slowly suppressed due to the direct inactivation of QB during 10 days of PG depletion, and was recovered rapidly within 10 h upon the PG re-addition. It is concluded that the loss of high-affinity PG (PGH) displaces QB directly. 3) Electron microscopy images of PG-depleted cells showed the specific suppression of division of mutant cells, which had developed thylakoid membranes attaching phycobilisomes (PBS). 4) Although the PG-depletion for 14 days decreased the chlorophyll/PBS ratio to about 1/4, florescence spectra/lifetimes were not modified indicating the flexible energy transfer from PBS to different numbers of PSII. Longer PG-depletion enhanced allophycocyanin fluorescence at 683 nm with a long 1.2 ns lifetime indicating the suppression of energy transfer from PBS to PSII. 5) Action sites of PGH, PGL and other PG molecules on PSII structure are discussed. 相似文献
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Vajravel Sindhujaa Laczkó-Dobos Hajnalka Petrova Nia Herman Éva Kovács Terézia Zakar Tomas Todinova Svetla Taneva Stefka Kovács Lászlo Gombos Zoltan Tóth Tünde Krumova Sashka 《Photosynthesis research》2020,145(2):179-188
Photosynthesis Research - The major light-harvesting system in cyanobacteria, the phycobilisome, is an essential component of the photosynthetic apparatus that regulates the utilization of the... 相似文献
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Eszter Karg Hajnalka Orvos Andrea Papp Nora Beck Sandor Turi Ilona Nemeth 《Free radical research》2013,47(5):555-561
In the neonatal period, there is a high iron load, while both the level and molar oxidase activity of ceruloplasmin are low. On the other hand, the neonatal xanthine oxidase (XO) activity is higher than later in life and XO has a significant iron-oxidizing capacity. We therefore studied the physiological contribution of XO to the ferroxidase activity of the plasma in 20 full-term newborn infants. Ferroxidase activity was measured spectrophotometrically, with Fe++ as substrate. The uric acid formed by XO was assayed by means of HPLC, with electrochemical detection.The total ferroxidase activity in the plasma was about one-fourth of the adult level and rapidly increased doubling within 3 days after birth. About 90% of the plasma ferroxidase activity was due to ceruloplasmin, the remainder being accounted for by ferroxidase II. The XO activity underwent a 30% (statistically non-significant) elevation at 24 h, though ferroxidase activity attributable to XO was not detected at any time.Accordingly, XO does not seem to add substantially to the total iron-oxidizing capacity of the plasma in the neonatal period. The high molar ferroxidase activity is probably of importance at the endothelial cell surface. 相似文献
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Thomas Riedel Hazuki Teshima J?rn Petersen Anne Fiebig Karen Davenport Hajnalka Daligault Tracy Erkkila Wei Gu Christine Munk Yan Xu Amy Chen Amrita Pati Natalia Ivanova Lynne A. Goodwin Patrick Chain John C. Detter Manfred Rohde Sabine Gronow Nikos C. Kyrpides Tanja Woyke Markus G?ker Thorsten Brinkhoff Hans-Peter Klenk 《Standards in genomic sciences》2013,8(3):389-402
Leisingera aquimarina Vandecandelaere et al. 2008 is a member of the genomically well characterized Roseobacter clade within the family Rhodobacteraceae. Representatives of the marine Roseobacter clade are metabolically versatile and involved in carbon fixation and biogeochemical processes. They form a physiologically heterogeneous group, found predominantly in coastal or polar waters, especially in symbiosis with algae, in microbial mats, in sediments or associated with invertebrates. Here we describe the features of L. aquimarina DSM 24565T together with the permanent-draft genome sequence and annotation. The 5,344,253 bp long genome consists of one chromosome and an unusually high number of seven extrachromosomal elements and contains 5,129 protein-coding and 89 RNA genes. It was sequenced as part of the DOE Joint Genome Institute Community Sequencing Program 2010 and of the activities of the Transregional Collaborative Research Centre 51 funded by the German Research Foundation (DFG). 相似文献
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Marco Dogs Sonja Voget Hazuki Teshima J?rn Petersen Karen Davenport Hajnalka Dalingault Amy Chen Amrita Pati Natalia Ivanova Lynne A. Goodwin Patrick Chain John C. Detter Sonja Standfest Manfred Rohde Sabine Gronow Nikos C. Kyrpides Tanja Woyke Meinhard Simon Hans-Peter Klenk Markus G?ker Thorsten Brinkhoff 《Standards in genomic sciences》2013,9(2):334-350
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Daligault H Lapidus A Zeytun A Nolan M Lucas S Del Rio TG Tice H Cheng JF Tapia R Han C Goodwin L Pitluck S Liolios K Pagani I Ivanova N Huntemann M Mavromatis K Mikhailova N Pati A Chen A Palaniappan K Land M Hauser L Brambilla EM Rohde M Verbarg S Göker M Bristow J Eisen JA Markowitz V Hugenholtz P Kyrpides NC Klenk HP Woyke T 《Standards in genomic sciences》2011,4(3):352-360
Haliscomenobacter hydrossis van Veen et al. 1973 is the type species of the genus Haliscomenobacter, which belongs to order "Sphingobacteriales". The species is of interest because of its isolated phylogenetic location in the tree of life, especially the so far genomically uncharted part of it, and because the organism grows in a thin, hardly visible hyaline sheath. Members of the species were isolated from fresh water of lakes and from ditch water. The genome of H. hydrossis is the first completed genome sequence reported from a member of the family "Saprospiraceae". The 8,771,651 bp long genome with its three plasmids of 92 kbp, 144 kbp and 164 kbp length contains 6,848 protein-coding and 60 RNA genes, and is a part of the Genomic Encyclopedia of Bacteria and Archaea project. 相似文献
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Ildikó Kasza Gy?rgy Várady Hajnalka Andrikovics Magdalena Koszarska Attila Tordai George L. Scheffer Adrienn Németh Gergely Szakács Balázs Sarkadi 《PloS one》2012,7(11)
We have developed a rapid, simple and reliable, antibody-based flow cytometry assay for the quantitative determination of membrane proteins in human erythrocytes. Our method reveals significant differences between the expression levels of the wild-type ABCG2 protein and the heterozygous Q141K polymorphic variant. Moreover, we find that nonsense mutations on one allele result in a 50% reduction in the erythrocyte expression of this protein. Since ABCG2 polymorphisms are known to modify essential pharmacokinetic parameters, uric acid metabolism and cancer drug resistance, a direct determination of the erythrocyte membrane ABCG2 protein expression may provide valuable information for assessing these conditions or for devising drug treatments. Our findings suggest that erythrocyte membrane protein levels may reflect genotype-dependent tissue expression patterns. Extension of this methodology to other disease-related or pharmacologically important membrane proteins may yield new protein biomarkers for personalized diagnostics. 相似文献