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401.
Jianfeng Ren Zhanhui Hou Haiyan Wang Ming-an Sun Xiao Liu Bin Liu Ximing Guo 《Marine biotechnology (New York, N.Y.)》2016,18(2):242-254
A large number of Crassostrea oysters are found in Asia-Pacific. While analyses of interspecific variation have helped to establish historical relationships among these species, studies on intraspecific variation are necessary to understand their recent evolutionary history and current forces driving population biology. We resequenced 18 and analyzed 31 mitogenomes of five Crassostrea species from China: Crassostrea gigas, Crassostrea angulata, Crassostrea sikamea, Crassostrea ariakensis, and Crassostrea hongkongensis. Our analysis finds abundant insertions, deletions, and single-nucleotide polymorphisms in all species. Intraspecific variation varies greatly among species with polymorphic sites ranging from 54 to 293 and nucleotide diversity ranging from 0.00106 to 0.00683. In all measurements, C. hongkongensis that has the narrowest geographic distribution exhibits the least sequence diversity; C. ariakensis that has the widest distribution shows the highest diversity, and species with intermediate distribution show intermediate levels of diversity. Low sequence diversity in C. hongkongensis may reflect recent bottlenecks that are probably exacerbated by human transplantation. High diversity in C. ariakensis is likely due to divergence of northern and southern China populations that have been separated without gene flow. The significant differences in mitogenome diversity suggest that the five sister species of Crassostrea have experienced different evolutionary forces since their divergence. The recent divergence of two C. ariakensis populations and the C. gigas/angulata species complex provides evidence for continued diversification and speciation of Crassostrea species along China’s coast, which are shaped by unknown mechanisms in a north–south divide. 相似文献
402.
In order to maintain a stable genome, cells need to detect and repair DNA damage before they complete the division cycle. To this end, cell cycle checkpoints prevent entry into the next cell cycle phase until the damage is fully repaired. Proper reentry into the cell cycle, known as checkpoint recovery, requires that a cell retains its original cell cycle state during the arrest. Here, we have identified Tousled‐like kinase 2 (Tlk2) as an important regulator of recovery after DNA damage in G2. We show that Tlk2 regulates the Asf1A histone chaperone in response to DNA damage and that depletion of Asf1A also produces a recovery defect. Both Tlk2 and Asf1A are required to restore histone H3 incorporation into damaged chromatin. Failure to do so affects expression of pro‐mitotic genes and compromises the cellular competence to recover from damage‐induced cell cycle arrests. Our results demonstrate that Tlk2 promotes Asf1A function during the DNA damage response in G2 to allow for proper restoration of chromatin structure at the break site and subsequent recovery from the arrest. 相似文献
403.
Dexuan Wang Shufang Pan Yixiao Xu Xiaohua Ye Xiaobi Ren Qiyi Zeng 《中国科学:生命科学英文版》2016,59(11):1189-1191
正Dear Editor,NCC(Na-Cl cotransporter)is a cotransporter mainly distributed in the distal tubule of the kidney,functioning to reabsorb sodium and chloride ions from the tubular fluid into the cells of the renal distal convoluted tubule.It is a 相似文献
404.
Red mud (RM)-Induced enhancement of iron plaque formation reduces arsenic and metal accumulation in two wetland plant species 总被引:2,自引:0,他引:2
J.X. Yang J. Yang X.Y. Zhou H.Y. Ren H.Z. Zhang 《International journal of phytoremediation》2016,18(3):269-277
Human activities have resulted in arsenic (As) and heavy metals accumulation in paddy soils in China. Phytoremediation has been suggested as an effective and low-cost method to clean up contaminated soils. A combined soil-sand pot experiment was conducted to investigate the influence of red mud (RM) supply on iron plaque formation and As and heavy metal accumulation in two wetland plant species (Cyperus alternifolius Rottb., Echinodorus amazonicus Rataj), using As and heavy metals polluted paddy soil combined with three rates of RM application (0, 2%, 5%). The results showed that RM supply significantly decreased As and heavy metals accumulation in shoots of the two plants due to the decrease of As and heavy metal availability and the enhancement of the formation of iron plaque on the root surface and in the rhizosphere. Both wetland plants supplied with RM tended to have more Fe plaque, higher As and heavy metals on roots and in their rhizospheres, and were more tolerant of As and heavy metal toxicity. The results suggest that RM-induced enhancement of the formation of iron plaque on the root surface and in the rhizosphere of wetland plants may be significant for remediation of soils contaminated with As and heavy metals. 相似文献
405.
Two star‐shaped tetranuclear Ru(II) complexes containing uncoordinated imidazole groups: synthesis,characterization, photophysical and pH sensing properties 下载免费PDF全文
Tetrapodal ligands H4L1 and H4L2 containing imidazole groups have been synthesized by the reaction of 1,10‐phenanthroline‐5,6‐dione with 1,2,4,5‐tetrakis[(4‐formylphenoxy)methyl]benzene and 1,2,4,5‐tetrakis[(3‐formylphenoxy)methyl]benzene, respectively, in presence of NH4OAc. Two star‐shaped complexes [{Ru(bpy)2}4(μ4‐H4L1)](PF6)8 and [{Ru(bpy)2}4(μ4‐H4L2)](PF6)8 (bpy = 2,2′‐bipyridine) have been prepared by refluxing Ru(bpy)2Cl2·2H2O and each ligand in ethylene glycol. The deprotonated complexes [{Ru(bpy)2}4(μ4‐L1)](PF6)4 and [{Ru(bpy)2}4(μ4‐L2)](PF6)4 have been obtained by the reaction of sodium methoxide with [{Ru(bpy)2}4(μ4‐H4L1)](PF6)8 and [{Ru(bpy)2}4(μ4‐H4L2)](PF6)8, respectively, in methanol. The pH effects on the UV–vis light absorption and emission spectra of both complexes have been studied, and ground‐ and excited‐state ionization constants of both complexes have been derived. The photophysical properties of both complexes are strongly dependent on the solution pH. They act as proton‐induced off–on–off luminescent sensors through two successive deprotonation processes of imidazole groups, with a maximum on–off ratio of 8 in buffer solution at room temperature. Theoretical calculations for the highest occupied molecular orbital (HOMO) and lowest occupied molecular orbital (LOMO) orbitals of bridging ligand are also presented for plausible explanations of the fluorescence changes. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
406.
蒲氏钩蝠蛾Thitarodes pui(Zhang et al.)是冬虫夏草寄主昆虫之一,其雄成虫触角感受器在求偶交配过程中起主要作用。本研究应用电子扫描显微镜对蒲氏钩蝠蛾雄成虫触角上的化学感受器进行观察。结果发现,雄成虫触角上有7种感受器,即毛形感受器、刺形感受器、锥形感受器、腔锥形感受器、钟形感受器、Bhm氏鬃毛和鳞形感受器,其中以毛形感受器和鳞形感受器数目最多,腔锥感受器又分为长栓形和短栓形两种。综合本研究结果与已知蝠蛾的触角感受器,发现蝠蛾触角感受器在表面结构、感受器类型等方面与其它鳞翅目昆虫存在差异。 相似文献
407.
Yuyue Ren Yunhe Gu Jinghua Wang Xiaoyun Li Ying Wang 《Cell cycle (Georgetown, Tex.)》2016,15(12):1545-1551
Silent information regulator type-1 (SIRT1) is the best-studied member of the Sirtuin (Sir2) family of nicotinamide dinucleotide (NAD)-dependent class III histone deacetylases (HDACs). Rrecently, it is suggested that SIRT1 may be involved in the development of malignant tumors including mouse lymphoma, but has not yet been explored in Angioimmunoblastic T-cell lymphoma (AITL). Therefore, we investigated the prevalence and the prognostic impact of SIRT1 expression in AITL. Immunohistochemical expression of SIRT1, p53 were evaluated by using a 2 mm core from 45 AITL patients. Positive expression of SIRT1 was seen in 71.11% (32 of 45) of patients and p53 expression were seen in 53.33% (24 of 45). SIRT1 and p53 expression were significantly associated with shorter PFS by univariate analysis (P=0.009 and P < 0.001, respectively), multivariate analysis also shows that SIRT1 expression relate to worse prognosis. We also suggest inferior survival in AITL with the combined expression of SIRT1 and clinical characteristics of high IPI scores, high clinical stage, increased serum LDH, decreased HGB and increased γ-Globulin. In conclusion, our results indicate that SIRT1 is strongly expressed in AITL and it act as a clinically significant prognostic indicator for AITL patients, may also serve as a therapeutic target in AITL. 相似文献
408.
Xin Sun Jian Liu Chongwen Xu Shou‐Ching Tang Hong Ren 《Journal of cellular and molecular medicine》2016,20(9):1779-1788
The ability of the classic tumour‐suppressive let‐7 family to inhibit carcinogenesis, tumour progression, recurrence and pluripotency of cancer stem cells has generated significant interest in the field of cancer research. Through suppressing and degrading downstream‐targeted mRNAs, let‐7 affected most aspects of cell biology. It is perplexing how let‐7 affects oncogenesis, as the large influx of new miRNAs and other kinds of non‐coding RNAs are continuously defined. In this review, we delineate the complex functions of let‐7 and discuss the future direction of let‐7 research. 相似文献
409.
Chinese Cretaceous larva exposes a southern Californian living fossil (Insecta,Coleoptera, Eucnemidae) 下载免费PDF全文
Chang Huali Jyrki Muona Pu Hanyong Xu Li Wang Chen Marianna Teräväinen Ren Dong Yang Qiang Zhang Xingliao Jia Songhai 《Cladistics : the international journal of the Willi Hennig Society》2016,32(2):211-214
Palaeoxenus sinensis Chang, Muona & Teräväinen sp. nov. (Coleoptera, Eucnemidae) is described on the basis of a Cretaceous larva found from the Yixian Formation in Huangbanjigou, Liaoning Province, China. The only previously known member of this clade is a southern Californian endemic, Dohrn's elegant eucnemid beetle (Palaeoxenus dohrni), a species that develops in conifers, especially the incense cedar (Calocedrus decurrens). The new find proves that the highly specialized main eucnemid lineages had evolved 123 Mya, before the main radiation of the angiosperms and probably as an adaptation to development in gymnosperms. 相似文献
410.