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JOHN W. McGARRY ABUBAKER M. GUSBI ANNE BAKER MARTIN J. R. HALL KALEFA EL MEGADEMI 《Medical and veterinary entomology》1992,6(3):255-260
During the screwworm eradication programme in Libya in 1991, trapped specimens of Cochliomyia hominivorax (Coquerel) were found infested with phoretic mites, Macrocheles muscaedomesticae (Scopoli), or parasitic mites, Trichotromidium muscarum (Riley). The possible sources of infestation and potential effects of mites on screwworm flies are discussed. 相似文献
424.
MACHHOUR GHAZALI MARIE-HELENE RODIER BRAHIM EL MOUDNI PHILIPPE BABIN BEATRICE FERNANDEZ JEAN-LOUIS JACQUEMIN 《The Journal of eukaryotic microbiology》1995,42(4):427-433
ABSTRACT. We demonstrated here the presence of proteins antigenically related to human erythroid spectrin in the parasitic protozoan Toxoplasma gondii . A high molecular weight doublet (M, 245-240,000), present in equimolar ratio, and low molecular weight polypeptides (M, 75,000) were reacted with monoclonal and polyclonal anti-human erythroid spectrin antibodies on electroblotted nitrocellulose sheets. Indirect immunofluorescence assay clearly showed that these proteins were localized in the anterior pole of the organism. Immunogold staining further revealed specific labeling of conoid, rhoptries, micronemes, and dense granules of the apical complex. The presence of the M, 245–240,000 doublet and the M, 75,000 spectrin-like proteins in the anterior pole of T. gondii may probably be consistent with a structural stabilizer function in its organciles which are suspected to be involved in the process of host cell invasion. 相似文献
425.
G Zavarise G Ghiazza G Grillo P Morino M Mondavio 《Bollettino della Società italiana di biologia sperimentale》1984,60(11):2143-2148
The aim of this work was the evaluation of the possible mutagenic effect of an antibiotic, the Cloxacillin. Therefore the authors have performed the analysis of the chromosomal alterations and the study of the SCE (Sister Chromatid Exchanges) induced with the exposition of cultures of lymphocytes to different concentrations of this drug. The work reveals that Cloxacillin induces chromosomal alterations at high concentrations, while at concentrations similar to its therapeutic levels the drug does not seem to interfere with human DNA. 相似文献
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E. J. FLACH H. OUHELLI D. WADDINGTON M. EL HASNAOUI 《Medical and veterinary entomology》1993,7(4):343-350
Abstract. The overall prevalence of Theileria species, mainly, if not exclusively, T.annulata, in 901 Hyalomma detritum detritum collected from cattle in the Doukkala region of Morocco over a period of 2 years was 21.5%. The quantity of infection (number of sporoblasts per infected tick) followed the negative binomial distribution with between one and 250 sporoblasts per infected tick. Infected ticks were found in eight of fourteen areas examined whilst T.annulata was present in all fourteen. There were significant differences in both the prevalence and the quantity of infection between ticks collected from different farms, and between nymphs collected in the autumn from these farms, and moulted in the laboratory, and adults collected in the following summer. The prevalence, but not the quantity, of infection was higher in female than in male ticks. No correlations were established between infection of engorged nymphs and the breed, sex and Theileria piroplasm parasitaemia of the host animal. However, calves infected a greater proportion of nymphs than adult cattle and the heavier the infestation of nymphs on an animal, up to a plateau, the higher the prevalence of infection in those nymphs. There were no differences in infection between ticks moulted at 24oC and 37oC, after the engorged nymphs had been stored at 18oC to simulate over-wintering. 相似文献
428.
EL Strzelecki U Gąsiorowska M Gorazdowska B Cader-Strzelecka M Pawełczak 《Mycotoxin Research》1988,4(2):89-96
Totally 39% out of 8371 feed and their component samples were contaminated by aflatoxin B1. Mean contamination was 36μg/kg with maximum yield 10100 μg/kg. Contamination of samples by total count of organisms, mean contamination and maximum yield, respectively was: 1) bacteria 99%, 2.2×106, 2.4×108; 2) proteolytic bacteria 94%, 1.2×105, 3.0×106;3) moulds 98%, 1.3×105, 9.0×106; 4) yeasts 44 %, 3.3×104, 3.6×106. The samples were contaminated in 92 % byAspergillus spp, in 71% byAspergillus flavus, in 83% byPenicillium spp, and in 20% byFusarium spp with mean contamination 8.3×104, 1.1×103, 4.2×104, 5.0×103 , and maximum yield 6.8×106, 1.0×105, 5.0×106, 1.5×106, respectively. Totally 8.5% of strains were aflatoxinogenic and 4.4% of the strains were isolated from feed and 21 % of the strains from grain/nut. 相似文献
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Tarek M. K. Motawi Yasser Bustanji Shohda A. EL‐Maraghy Mutasem O. Taha Mohamed A. S. Al Ghussein 《Journal of biochemical and molecular toxicology》2013,27(9):425-436
Naproxen and cromolyn were investigated as new inhibitors of glycogen synthase kinase‐3β (GSK‐3β) in an attempt to explain their hypoglycemic properties. Study included simulated docking experiments, in vitro enzyme inhibition assay, and in vivo validations. Both drugs not only were optimally fitted within a GSK‐3β binding pocket via several attractive interactions with key amino acids but also exhibited potent in vitro enzymatic inhibitory activities of IC50 1.5 and 2.0 µM for naproxen and cromolyn, respectively. In vivo experiments illustrated that both drugs significantly reduced serum glucose and increased hepatic glycogen‐ and serum insulin levels in normal and type II diabetic Balb/c mice models. In obese animal model, both drugs exhibited significant reduction in mice weights, serum glucose, and resistin levels along with significant elevation in serum insulin, C‐peptide, and adiponectin values. It can be concluded that naproxen and cromolyn are novel GSK‐3β inhibitors and can help in management of diabetes and obesity. © 2013 Wiley Periodicals, Inc. J BiochemMol Toxicol 27:425–436, 2013; View this article online at wileyonlinelibrary.com . DOI 10.1002/jbt.21503 相似文献