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401.
The size, location and structure of Pt clusters in H-mordenite have been investigated by molecular mechanics energy minimization and molecular dynamics simulation techniques using the Catalysis software of Molecular Simulations (MSI). Lattice energy minimizations are performed to study the effects of the specific framework aluminum positions on the location and stability of monoatomic Pt sites in H-mordenite. The lattice energies relative to the siliceous platinum-aluminosilicate structure reveal that the stability of a single Pt atom in H-mordenite is remarkably influenced by the specific location of the Al atoms in the lattice. At the studied Si/Al ratio of two Al ions per unit cell, a stabilization of the H-mordenite lattice upon Pt deposition is obtained. Moreover, lattice energy calculations on Pt/aluminosilicate mordenites of different metal contents per unit cell have been performed. An optimum size for the aggregate confined to the 12-ring main channel that is almost independent of the Pt content per mordenite unit cell has been found. The structural features of the resulting clusters at the end of molecular dynamics simulations on Pt/alumina-mordenites reflect a strong metal-zeolite interaction. The present results are consistent with a previous molecular dynamics simulation study on the structure of platinum deposited on SiO2 surfaces. 相似文献
402.
T. A. I. Grillo Dorothea L. Baxter-Grillo J. O. A. Abegunde 《Histochemistry and cell biology》1978,59(1):73-74
Summary The original metal-salt technique of Gomori (1948a) employing p-chloranilidophosphonic acid as a substrate for the demonstration of the activity of phosphoamidase has been used with varying success by a number of investigators for light microscopy, Cyclophosphamide (endoxan) which is a cytotoxic drug known to activate phosphoamidase and other lysosomal enzymes in neoplasm (Grillo, 1971) is proposed as another substrate for the enzyme for both light and electron microscopy. 相似文献
403.
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406.
V. Battaglia S. Grancara M. Mancon C. Cravanzola S. Colombatto M. A. Grillo G. Tempera E. Agostinelli A. Toninello 《Amino acids》2010,38(2):423-430
The diamine agmatine (AGM), exhibiting two positive charges at physiological pH, is transported into rat brain mitochondria
(RBM) by an electrophoretic mechanism, requiring high membrane potential values and exhibiting a marked non-ohmic force–flux
relationship. The mechanism of this transport apparently resembles that observed in rat liver mitochondria (RLM), but there
are several characteristics that strongly suggest the presence of a different transporter of agmatine in RBM. In this type
of mitochondria, the extent of initial binding and total accumulation is higher and lower, respectively, than that in liver;
saturation kinetics and the flux–voltage relationship also exhibit different trends, whereas idazoxan and putrescine, ineffective
in RLM, act as inhibitors. The characteristics of agmatine uptake in RBM lead to the conclusion that its transporter is a
channel with two asymmetric energy barriers, showing some characteristics similar to those of the imidazoline receptor I2 and the sharing with the polyamine transporter. 相似文献
407.
F A Pisanti S Frascatore E Vuttariello A Grillo 《Biochemical medicine and metabolic biology》1987,37(2):265-267
The administration of 8 mg of acetylhomocysteinethiolactone/kg body wt determines a significant (P less than 0.001) increase in rat erythrocyte superoxide dismutase activity. 相似文献
408.
Metabolism and function of polyamines 总被引:1,自引:0,他引:1
M A Grillo 《The International journal of biochemistry》1985,17(9):943-948
409.
410.
The molecular organization of the beta-globin complex of the deer mouse, Peromyscus maniculatus 总被引:1,自引:0,他引:1
Padgett RW; Loeb DD; Snyder LR; Edgell MH; Hutchison CA d 《Molecular biology and evolution》1987,4(1):30-45
Recombinant DNA clones have been isolated that contain 80 kb of the
beta-globin complex from the deer mouse, Peromyscus maniculatus.
Comparisons of this complex with that from the laboratory mouse, Mus
domesticus (with an order 5'-Hbby, Hbb-bhO, Hbb-bhl, Hbb-bh2, Hbb-bh3,
Hbb-bl, Hbb-b2 3') highlight organizational trends in the beta-globin
complex since the two species diverged. Unlike other mammals studied thus
far, the deer mouse possesses three adult genes. Partial sequence analysis
indicates that each of the three adult genes is intact and hence may be
functional. Hybridization of one of the two Mus pseudogenes, Hbb-bh3, to
genomic blots from Peromyscus reveals that it has a homologous counterpart
in Peromyscus. Homologous genes to the two gamma-like Mus genes, Hbb-bhO
and Hbb-bhl, are also found in Peromyscus. The strong hybridization between
the Hbb-bhl genes and significant nucleotide similarity between the Hbb-bhO
genes suggest that both pairs are important for the ontogeny of these mice
although no known product has been identified for the Hbb-bhO genes. The
presence of Hbb-bhO and Hbb-bhl in Peromyscus suggests that the duplication
that created this related gene set occurred before the two lineages
diverged. A single gene for Hbb-y has been isolated from Peromyscus. The
adult region in Peromyscus has undergone significant divergence from the
same region in Mus, having three rather than two adult genes, the
acquisition of at least 15 kb of extra DNA relative to Mus, and possibly
the loss of the Hbb-bh2 pseudogene. The nonadult region of the complex, in
contrast, contains the same set of genes apparently distributed over the
same amount of DNA as in the Mus beta- globin complex. This observation
suggests that the embryonic region of the complex is more evolutionarily
stable than the adult region.
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