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31.
Yvonne Grimm-Jørgensen S.E. Pfeiffer J.F. McKelvy 《Biochemical and biophysical research communications》1976,70(1):167-173
Immunoreactive thyrotropin releasing factor (TRF) was detected in homogenates of two clonal cell lines, BN1010-1 and BN1010-3, derived from a rat central nervous system tumor. TRF was present in logarithmically-growing cells; daily medium changes with slightly acid culture medium (pH 6.8) greatly increased the TRF content of these cells. In contrast, TRF could not be detected in stationary phase cells. TRF peptidases were <1% as active in homogenates of BN1010 cells as those in homogenates of guinea pig brain or hypothalamus. It is expected that these cells will provide an excellent model system for the study of various aspects of TRF metabolism. 相似文献
32.
Gaël Clement 《Palaeontology》2002,45(3):577-593
Remains of two large sarcopterygians are described from Famennian deposits in Belgium. One of them is referred to Eusthenodon wängsjöi Jarvik; it is the first occurrence of this genus in Belgium. The other, much larger one, appears to be a tristichopterid. It has a postspiracular; size and shape of the mandible similar to those of Platycephalichthys skuenicus and P. bischoffi ; snout and cheek patterns close to those of Eusthenodon ; unusual shape of the supratemporal resembling that of Hyneria , Mandageria and Platycephalichthys skuenicus ; and tooth histology quite similar to that of Eusthenodon and Platycephalichthys . 相似文献
33.
An abnormal terminal X-Y interchange accounts for most but not all cases of human XX maleness 总被引:14,自引:0,他引:14
To determine if human XX maleness results from an abnormal chromosomal X-Y interchange, we studied the inheritance of the paternal pseudoautosomal region in nine patients. Those six patients in whom Y-specific DNA was found (Y(+)) inherited the entire pseudoautosomal region from the paternal Y chromosome and lost that of the paternal X chromosome. Moreover, in three Y(+) cases, we observed the deletion of a paternal Xp locus tightly linked to the pseudoautosomal region. These results definitively show that an abnormal and terminal X-Y interchange during paternal meiosis causes Y(+)XX maleness. In contrast, no abnormal X-Y interchange was observed in any of the three Y(-) cases analyzed, suggesting that maleness can occur in the absence of any Y-specific DNA. 相似文献
34.
Summary The reductive cleavage of the aclacinomycins A (I), Y (II), and B (III) by intact mycelia or subcellular fractions of the producer strain S. spec. AM 33352/F43 is suppressed in the presence of uncouplers, complex-forming agents, detergents, and some metal anions such as chromate. Increased concentration of the latter in complete cultures caused rearrangement of I to III. 相似文献
35.
Summary A mutant ofS.
chrysomallus with a D-glucose isomerase inducible by D-glucose or its catabolites was characterized. In contrast to the wild-type strain it showed a decreased catabolite repression by D-glucose of D-xylose consumption and a constitutive pentose phosphate pathway as well. A hypothesis concerning altered induction pattern of its D-glucose isomerase is discussed. 相似文献
36.
I. I. Moraru Mioara Manciulea Anca Călugăru Gr. Ghyka L. M. Popescu 《Bioscience reports》1987,7(9):731-736
A novel approach was used to assess the role of phosphoinositide hydrolysis in the mitogenic action of phytohemagglutinin (PHA) or concanavalin A (ConA). The treatment of human peripheral blood leukocytes (PBL) with monospecific antibodies against phospholipase C (PLC) produced a dose-dependent inhibition (up to 100%) of PHA (10 g/ml) or ConA (25 g/ml) proliferative effects. Thus, the activation of membrane-bound PLC is asine-qua-non condition for lectin-induced proliferation of T lymphocytes. The key-role of PLC versus protein kinase C (PKC) is stressed by the fact that the inhibition of PKC with Hidaka's compound H-7 (40 M) produced only a partial blockade (about 25%) of lectin mitogenic effect.To whom correspondence should be addressed. 相似文献
37.
A malate dehydrogenase was purified from the unicellular green alga Chlorogonium elongatum Dangeard. The enzyme was localized in the mitochondria by immunogold electron microscopy and was found to be present on the cristae. The concentration of the enzyme is regulated by acetate and light. In cells cultured heterotrophically with acetate as carbon source the activity and the concentration of the enzyme is 5- to 6-fold higher than in autotrophic cells. In mixotrophically cultured cells (light and acetate) the enzyme level attains only half of the value of that in heterotrophic cells. Acetate induces an increase of the enzyme concentration while light has an inhibitory effect on this process. 相似文献
38.
The N2O flux from the surface of grass-covered pots was only significant following grass maturing. Removal of the above-ground plant
material resulted in an immediate and long-lasting increase in N2O production in the soil. The results suggest that easily available organic matter from the roots stimulates the denitrification
when the plants are damaged. Grass cutting might therefore result in a marked nitrogen loss through denitrification. The quantitative
effect was equal in soil with and without succinate added. The size of the anaerobic zone around the roots is therefore sufficient
to allow for denitrification activity mediated by increased organic matter availability because of plant cutting. 相似文献
39.
The influence of arterial hypoxia on bone marrow pressure, regional blood flow and oxygen and carbon dioxide tensions was investigated by simultaneous and continuous measurements in the femoral condyles of 8 rabbits. Arterial hypoxia was obtained by hypoventilation. The subchondral gas tensions and regional blood flow were measured by a previously described technique based on mass spectrometry. Arterial hypoxia caused a significant decrease in subchondral oxygen tension and an increase in subchondral carbon dioxide tension. There was no significant change in bone marrow pressure and regional blood flow. 相似文献
40.