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Grauso Laura Emrick Stefano de Falco Bruna Lanzotti Virginia Bonanomi Giuliano 《Phytochemistry Reviews》2019,18(4):1115-1132
Phytochemistry Reviews - Phytoalimurgy is a term that derives from Greek and Latin by combination of the words φυτόν, which meaning plant, and alimenta urgentia, indicating... 相似文献
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The phytophagous insects of the Tephritidae family commonly referred to as “true fruit flies” offer different case histories
of successful invasions. Mankind has played an important role in altering the distributions of some of the more polyphagous
and oligophagous species. However, the question arises why only a few species have become major invaders. The understanding
of traits underlying adaptation in different environments is a major topic in invasion biology. Being generalists or specialists,
along the K–r gradient of the growth curve, make a difference in term of food resources exploitation and interspecies competition and displacement.
The species of the genus Ceratitis are good examples of r-strategists. The genetic and biological data of the most notorious Ceratitis species, the Mediterranean fruit fly Ceratitis capitata (medfly), are reviewed to investigate the traits and behaviours that make the medfly an important invader. It can be learnt
from medfly, that invasions in a modern global trade network tend to be due to multiple introductions. This fact allows a
maintenance or enhancement of genetic variability in the adventive populations, which in turn increases their potential invasiveness.
Our current knowledge of the medfly genome opens the way for future studies on functional genomics. 相似文献
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Alessio Atzori Viveka N. Malviya Giuliano Malloci Jürg Dreier Klaas M. Pos Attilio V. Vargiu Paolo Ruggerone 《生物化学与生物物理学报:生物膜》2019,1861(1):62-74
Understanding the molecular determinants for recognition, binding and transport of antibiotics by multidrug efflux systems is important for basic research and useful for the design of more effective antimicrobial compounds. Imipenem and meropenem are two carbapenems whose antibacterial activity is known to be poorly and strongly affected by MexAB-OprM, the major efflux pump transporter in Pseudomonas aeruginosa. However, not much is known regarding recognition and transport of these compounds by AcrAB-TolC, which is the MexAB-OprM homologue in Escherichia coli and by definition the paradigm model for structural studies on efflux pumps. Prompted by this motivation, we unveiled the molecular details of the interaction of imipenem and meropenem with the transporter AcrB by combining computer simulations with biophysical experiments. Regarding the interaction with the two main substrate binding regions of AcrB, the so-called access and deep binding pockets, molecular dynamics simulations revealed imipenem to be more mobile than meropenem in the former, while comparable mobilities were observed in the latter. This result is in line with isothermal titration calorimetry, differential scanning experiments, and binding free energy calculations, indicating a higher affinity for meropenem than imipenem at the deep binding pocket, while both sharing similar affinities at the access pocket. Our findings rationalize how different physico-chemical properties of compounds reflect on their interactions with AcrB. As such, they constitute precious information to be exploited for the rational design of antibiotics able to evade efflux pumps. 相似文献
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M Rahimnejad GD Najafpour AA Ghoreyshi F Talebnia GC Premier G Bakeri JR Kim SE Oh 《Journal of microbiology (Seoul, Korea)》2012,50(4):575-580
Microbial fuel cells (MFCs) have been shown to be capable of clean energy production through the oxidation of biodegradable organic waste using various bacterial species as biocatalysts. In this study we found Saccharomyces cerevisiae, previously known electrochemcially inactive or less active species, can be acclimated with an electron mediator thionine for electrogenic biofilm formation in MFC, and electricity production is improved with facilitation of electron transfer. Power generation of MFC was also significantly increased by thionine with both aerated and non-aerated cathode. With electrochemically active biofilm enriched with swine wastewater, MFC power increased more significantly by addition of thionine. The optimum mediator concentration was 500 mM of thionine with S. cerevisae in MFC with the maximum voltage and current generation in the microbial fuel cell were 420 mV and 700 mA/m(2), respectively. Cyclic voltametry shows that thionine improves oxidizing and reducing capability in both pure culture and acclimated biofilm as compared to non-mediated cell. The results obtained indicated that thionine has great potential to enhance power generation from unmediated yeast or electrochemically active biofilm in MFC. 相似文献
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Jaguars Panthera onca inhabiting tropical or subtropical evergreen moist forest have often been classified as opportunistic predators because they consume prey relative to its availability. However, these studies failed to address simultaneously the distribution of predator and prey through time and space, which may lead to an incomplete or erroneous understanding of jaguar foraging strategies. In this study, we reconstructed jaguar diet from scat, and used camera traps to investigate jaguar prey availability and the distribution of jaguar and its prey through space and time. We focused our examination of predator–prey temporal and spatial relations on forest infrastructure comprising man-made paths, small mammal trails, tapir Tapirus bairdi trail and trail-less, forested areas as they represent distinct habitats for prey selection. Overall, we observed high overlap between the prey used and available, suggestive of opportunistic foraging. However, jaguars exhibited selective tendencies in discriminating between larger prey. Jaguars used collared peccary Tayassu tajacu greater than its availability, while preying upon the equally abundant and similarly distributed white-lipped peccary Tayassu pecari and tapir less than predicted based upon availability. Armadillo Dasypus novemcinctus and paca Agouti paca , 56.6% of total consumption, were consumed relative to availability but exhibited low spatial overlap with jaguar. Armadillo and paca used trail-less, forested areas and small mammal trails not used by jaguar and were photographed more frequently at greater distances from man-made paths, major thoroughfares for jaguars. This study suggests that although forest jaguars use prey relative to its abundance, jaguars may rely on foraging strategies other than chance encounters for exploiting prey. 相似文献
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