全文获取类型
收费全文 | 5065篇 |
免费 | 322篇 |
国内免费 | 2篇 |
出版年
2023年 | 33篇 |
2022年 | 54篇 |
2021年 | 95篇 |
2020年 | 61篇 |
2019年 | 90篇 |
2018年 | 117篇 |
2017年 | 108篇 |
2016年 | 135篇 |
2015年 | 258篇 |
2014年 | 254篇 |
2013年 | 403篇 |
2012年 | 428篇 |
2011年 | 400篇 |
2010年 | 238篇 |
2009年 | 205篇 |
2008年 | 339篇 |
2007年 | 315篇 |
2006年 | 267篇 |
2005年 | 265篇 |
2004年 | 231篇 |
2003年 | 230篇 |
2002年 | 209篇 |
2001年 | 30篇 |
2000年 | 22篇 |
1999年 | 45篇 |
1998年 | 54篇 |
1997年 | 36篇 |
1996年 | 37篇 |
1995年 | 37篇 |
1994年 | 33篇 |
1993年 | 20篇 |
1992年 | 25篇 |
1991年 | 13篇 |
1990年 | 24篇 |
1989年 | 25篇 |
1988年 | 14篇 |
1987年 | 10篇 |
1986年 | 20篇 |
1985年 | 11篇 |
1984年 | 25篇 |
1983年 | 13篇 |
1982年 | 19篇 |
1981年 | 10篇 |
1980年 | 17篇 |
1979年 | 13篇 |
1977年 | 13篇 |
1976年 | 13篇 |
1975年 | 15篇 |
1974年 | 8篇 |
1971年 | 8篇 |
排序方式: 共有5389条查询结果,搜索用时 31 毫秒
191.
192.
193.
BackgroundThe main behaviour change intervention available for coronary heart disease (CHD) patients is cardiac rehabilitation. There is little recognition of what the active ingredients of behavioural interventions for CHD might be. Using a behaviour change technique (BCT) framework to code existing interventions may help to identify this. The objectives of this systematic review are to determine the effectiveness of CHD behaviour change interventions and how this may be explained by BCT content and structure.ConclusionsBehaviour change interventions for CHD patients appear to have a positive impact on a number of outcomes. Using an existing BCT taxonomy to code the interventions helped us to understand which were the most commonly used techniques, providing information and goal setting, but not the active components of these complex interventions. 相似文献
194.
Giacomo De Luca Silvia Laura Bosello Francesca Augusta Gabrielli Giorgia Berardi Federico Parisi Manuela Rucco Giovanni Canestrari Francesco Loperfido Leonarda Galiuto Filippo Crea Gianfranco Ferraccioli 《PloS one》2016,11(4)
BackgroundArrhythmias are frequent in Systemic Sclerosis (SSc) and portend a bad prognosis, accounting alone for 6% of total deaths. Many of these patients die suddenly, thus prevention and intensified risk-stratification represent unmet medical needs. The major goal of this study was the definition of ECG indexes of poor prognosis.MethodsWe performed a prospective cohort study to define the role of 24h-ECG-Holter as an additional risk-stratification technique in the identification of SSc-patients at high risk of life-threatening arrhythmias and sudden cardiac death (SCD). One-hundred SSc-patients with symptoms and/or signs suggestive of cardiac involvement underwent 24h-ECG-Holter. The primary end-point was a composite of SCD or need for implantable cardioverter defibrillator (ICD).ResultsFifty-six patients (56%) had 24h-ECG-Holter abnormalities and 24(24%) presented frequent ventricular ectopic beats (VEBs). The number of VEBs correlated with high-sensitive cardiac troponin T (hs-cTnT) levels and inversely correlated with left-ventricular ejection fraction (LV-EF) on echocardiography. During a mean follow-up of 23.1±16.0 months, 5 patients died suddenly and two required ICD-implantation. The 7 patients who met the composite end-point had a higher number of VEBs, higher levels of hs-cTnT and NT-proBNP and lower LV-EF (p = 0.001 for all correlations). All these 7 patients had frequent VEBs, while LV-EF was not reduced in all and its range was wide. At ROC curve, VEBs>1190/24h showed 100% of sensitivity and 83% of specificity to predict the primary end-point (AUROC = 0.92,p<0.0001). Patients with VEBS>1190/24h had lower LV-EF and higher hs-cTnT levels and, at multivariate analysis, the presence of increased hs-cTnT and of right bundle branch block on ECG emerged as independent predictors of VEBs>1190/24h. None of demographic or disease-related characteristics emerged as predictors of poor outcome.ConclusionsVEBS>1190/24h identify patients at high risk of life-threatening arrhythmic complications. Thus, 24h-ECG-Holter should be considered a useful additional risk-stratification test to select SSc-patients at high-risk of SCD, in whom an ICD-implantation could represent a potential life-saving intervention. 相似文献
195.
196.
197.
Beryl Royer-Bertrand Matteo Torsello Donata Rimoldi Ikram El Zaoui Katarina Cisarova Rosanna Pescini-Gobert Franck Raynaud Leonidas Zografos Ann Schalenbourg Daniel Speiser Michael Nicolas Laureen Vallat Robert Klein Serge Leyvraz Giovanni Ciriello Nicolò Riggi Alexandre P. Moulin Carlo Rivolta 《American journal of human genetics》2016,99(5):1190-1198
198.
On‐chip assessment of human primary cardiac fibroblasts proliferative responses to uniaxial cyclic mechanical strain
下载免费PDF全文
![点击此处可从《Biotechnology and bioengineering》网站下载免费的PDF全文](/ch/ext_images/free.gif)
199.
200.