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A previous experiment(Herzfeld & Taub, 1977) demonstrated that slide projections and explicit suggestions relating to thermal experiences can significantly augment temperature self-regulations training(.5° F,p<.05). However, the experimental design was thought to result in an underestimate of the magnitude of the effect, since each subject served as his own control and could therefore make use on nonsuggestion training days of material provided on training days. In this experiment, separate groups of subjects either were given feedback combined with the suggestion procedure on each of 8 training days or were given feedback alone. The mean temperature self-regulation of the suggestion group(2.01° F) was significantly better than the self-regulation(.73) of the nonsuggestion group(t test,p<.01).a difference of 1.28° F. 相似文献
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Summary Osteogenesis imperfecta (OI) is a phenotype with clinical and biochemical heterogeneity. We report here that expression of the OI phenotype extends to the level of dermal fibroblast morphology in vitro. Growth characteristics and morphology of control (n=6) and OI cell strains (n=10, representing the four major OI categories, Sillence classification) were compared by measuring the following: (i) days required in culture to reach confluence after plating at uniform density; (ii) cell density at confluence; (iii) width and length of cells (measured on phase contrast micrographs at 300xmagnification). Our results show that: (i) OI fibroblasts take longer (11–27 days, mean 20 days) than control cells (10–19 days, mean 16 days) to reach stationary phase; (ii) all OI phenotypes achieve a lower cell density (0.87x106 cells/P60, range 0.3–1.6x106) at stationary phase relative to control cells (2.2x106 cells/P60, range 1.7–2.6x106; F4,77=56.1, p<0.01, indicating that OI cells are larger than normal). Cell shape (expressed as the width: length ratio) was also abnormal in OI cells. (F4,730=37.6, p<0.01), types I and II OI cells have significantly increased ratios (p<0.01) relative to control, type III, and type IV cells. Intra-group phenotypic heterogeneity was also apparent in the OI categories and also within the control population. These findings confirm deviant morphologic phenotypes in OI dermal fibroblasts and further demonstrate interindividual heterogeneity in the expression of genes that determine size and shape of dermal fibroblasts in both OI and normal donors.Publication No. 84013 from the Montreal Children's Hospital Research Institute 相似文献
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Dennis W. Jung Gerald P. Brierley 《Biochemical and biophysical research communications》1982,106(4):1372-1377
Heart mitochondria respiring in the presence of Pi release endogenous K+ to a sucrose medium when an uncoupler is added. The uncoupled mitochondria retain K+, however, if the oxidation of NAD(P)H is prevented by the addition of rotenone or antimycin. Addition of rotenone, once the uncoupler-dependent K+-efflux has been initiated, results in a rapid reduction of NAD(P) and a simultaneous decrease in permeability to K+. These changes are independent of respiration. The results suggest that a latent pathway for K+-permeability is present in the membrane, that it can be opened and closed reversibly, and that it reflects, either directly or indirectly, the redox status of mitochondrial pyridine nucleotides. The possible relationship of this putative pathway to those available for Ca2+ uptake and release is considered. 相似文献
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Franz M. Wuketits 《Biology & philosophy》1986,1(2):191-206
Recently, biologist and philosophers have been much attracted by an evolutionary view of knowledge, so-called evolutionary epistemology. Developing this insight, the present paper argues that our cognitive abilities are the outcome of organic evolution, and that, conversely, evolution itself may be described as a cognition process. Furthermore, it is argued that the key to an adequate evolutionary epistemology lies in a system-theoretical approach to evolution which grows from, but goes beyond, Darwin's theory of natural selection. 相似文献
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Ulrike Rosenfellner Franz Zehetner Martin H. Gerzabek 《Soil & Sediment Contamination》2009,18(6):685-687
Data from eight published studies were combined to show that the influence of traffic density on Pb contents in roadside soils increases with proximity to the road. 相似文献
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The histologic properties of pleural adipose organs were studied in 14 newborns. These organs contain milky spots, in which lymphocytes, macrophages and plurivacuolated fat cells are present. The milky spots have a mesothelial covering, persist to the age of 9 months and seem to act as defence devices and a site of fluid exchange. 相似文献