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31.
32.
JANNE RIIHIMÄKI HARRI VEHVILÄINEN PEKKA KAITANIEMI JULIA KORICHEVA 《Ecological Entomology》2006,31(3):227-235
Abstract. 1. Vegetation structural complexity is an important factor influencing ecological interactions between different trophic levels. In order to investigate relationships between the architecture of trees, the presence of arthropod predators, and survival and parasitism of the autumnal moth Epirrita autumnata Borkhausen, two sets of experiments were conducted.
2. In one experiment, the architectural complexity of mountain birch was manipulated to separate the effects of plant structure and age. In the other experiment the trees were left intact, but chosen to represent varying degrees of natural complexity. Young autumnal moth larvae were placed on the trees and their survival was monitored during the larval period.
3. The larvae survived longer in more complex trees if predation by ants was prevented with a glue ring, whereas in control trees smaller canopy size improved survival times in one experiment. The density of ants observed in the trees was not affected by canopy size but spider density was higher on smaller trees. The effect of canopy structure on larval parasitism was weak; larger canopy size decreased parasitism only in one year. Until the fourth instar the larvae travelled shorter distances in trees with reduced branchiness than in trees with reduced foliage or control treatments. Canopy structure manipulation by pruning did not alter the quality of leaves as food for larvae.
4. The effect of canopy structure on herbivore survival may depend on natural enemy abundance and foraging strategy. In complex canopies herbivores are probably better able to escape predation by ambushing spiders but not by actively searching ants. 相似文献
2. In one experiment, the architectural complexity of mountain birch was manipulated to separate the effects of plant structure and age. In the other experiment the trees were left intact, but chosen to represent varying degrees of natural complexity. Young autumnal moth larvae were placed on the trees and their survival was monitored during the larval period.
3. The larvae survived longer in more complex trees if predation by ants was prevented with a glue ring, whereas in control trees smaller canopy size improved survival times in one experiment. The density of ants observed in the trees was not affected by canopy size but spider density was higher on smaller trees. The effect of canopy structure on larval parasitism was weak; larger canopy size decreased parasitism only in one year. Until the fourth instar the larvae travelled shorter distances in trees with reduced branchiness than in trees with reduced foliage or control treatments. Canopy structure manipulation by pruning did not alter the quality of leaves as food for larvae.
4. The effect of canopy structure on herbivore survival may depend on natural enemy abundance and foraging strategy. In complex canopies herbivores are probably better able to escape predation by ambushing spiders but not by actively searching ants. 相似文献
33.
Sergey A. Shiryaev Albert G. Remacle Alexei Y. Savinov Andrei V. Chernov Piotr Cieplak Ilian A. Radichev Roy Williams Tatiana N. Shiryaeva Katarzyna Gawlik Tatiana I. Postnova Boris I. Ratnikov Alexei M. Eroshkin Khatereh Motamedchaboki Jeffrey W. Smith Alex Y. Strongin 《The Journal of biological chemistry》2009,284(44):30615-30626
34.
35.
KK Chan B Dassanayake R Deen RE Wickramarachchi SK Kumarage S Samita KI Deen 《World journal of surgical oncology》2010,8(1):1-11
Introduction
Male breast cancer (MBC) is a rare, yet potentially aggressive disease. Although literature regarding female breast cancer (FBC) is extensive, little is known about the etiopathogenesis of male breast cancer. Studies from our laboratory show that MBCs have a distinct immunophenotypic profile, suggesting that the etiopathogenesis of MBC is different from FBCs. The aim of this study was to evaluate and correlate the immunohistochemical expression of cell cycle proteins in male breast carcinoma to significant clinico-biological endpoints.Methods
75 cases of MBC were identified using the records of the Saskatchewan Cancer Agency over 26 years (1970-1996). Cases were reviewed and analyzed for the immunohistochemical expression of PCNA, Ki67, p27, p16, p57, p21, cyclin-D1 and c-myc and correlated to clinico-biological endpoints of tumor size, node status, stage of the disease, and disease free survival (DFS).Results
Decreased DFS was observed in the majority of tumors that overexpressed PCNA (98%, p = 0.004). The overexpression of PCNA was inversely correlated to the expression of Ki67 which was predominantly negative (78.3%). Cyclin D1 was overexpressed in 83.7% of cases. Cyclin D1 positive tumors were smaller than 2 cm (55.6%, p = 0.005), had a low incidence of lymph node metastasis (38.2%, p = 0.04) and were associated with increased DFS of >150 months (p = 0.04). Overexpression of c-myc (90%) was linked with a higher incidence of node negativity (58.3%, p = 0.006) and increased DFS (p = 0.04). p27 over expression was associated with decreased lymph node metastasis (p = 0.04). P21 and p57 positive tumors were related to decreased DFS (p = 0.04). Though p16 was overexpressed in 76.6%, this did not reach statistical significance with DFS (p = 0.06) or nodal status (p = 0.07).Conclusion
Aberrant cell cycle protein expression supports our view that these are important pathways involved in the etiopathogenesis of MBC. Tumors with overexpression of Cyclin D1 and c-myc had better outcomes, in contrast to tumors with overexpression of p21, p57, and PCNA with significantly worse outcomes. P27 appears to be a predictive marker for lymph nodal status. Such observation strongly suggests that dysregulation of cell cycle proteins may play a unique role in the initiation and progression of disease in male breast cancer. Such findings open up new avenues for the treatment of MBC as a suitable candidate for novel CDK-based anticancer therapies in the future. 相似文献36.
ANTTI RÖNKÄ KARI KOIVULA MIKKO OJANEN VELI-MATTI PAKANEN MARKO POHJOISMÄKI KARI RANNIKKO & PENTTI RAUHALA 《Ibis》2006,148(1):55-65
We measured nesting success of the Temminck's Stint Calidris temminckii along the Finnish Bothnian Bay coast during 19 breeding seasons (1983–2001) and conducted a population census (1999–2002). We found 105 pairs, showing a marked decline from the previous survey (170 pairs 1987–95). Of the 424 'known-fate' nests, 47% hatched. Depredation caused 79.9% of the nest losses. Nesting failures increased from 1983–91 to 1992–2001 owing to a rise in nest predation. The proportion of failed nests that failed because of predation rose from 48.9 to 87.7%. When only depredated nests were considered as losses, Mayfield nest survival probability over the incubation period dropped from 69 to 31% (461 nests). This pattern emerged both in man-made and in natural habitats. Survival probability was independent of habitat type (natural vs. man-made). In an experiment involving videotaping of dummy nests, Common Gull Larus canus and Ruddy Turnstone Arenaria interpres were found to be the most important egg predators. 相似文献
37.
Bildstein Keith L. Gawlik Dale E. Ferral Dan P. Brisbin I. Lehr Wein Gary R. 《Hydrobiologia》1994,279(1):71-82
We compared wading bird use of a newly created 405-ha reactor cooling reservoir (L-Lake) at the Savannah River Site, near Aiken, South Carolina, with that of two similar > 25-year-old reservoirs (1130-ha Par Pond and 87-ha Pond B) at the same site. L-Lake was constructed in 1984–1985 and filled in late 1985. Approximately 25% of the shoreline of L-Lake was planted with lacustrine vegetation in early 1987 in an attempt to speed the establishment of a self-sustaining balanced biological community (BBC) at the reservoir. Even so, during the course of our studies, L-Lake had considerably less wetland vegetation, especially floating-leaved species such as yellow nelumbo (Nelumbo lutea), than did either of the two older reservoirs.Sixty-three surveys of the avian communities using the three reservoirs were conducted between fall of 1987 and summer of 1989. These surveys indicated that (1) at least seven species of wading birds (order: Ciconiiformes) used L-Lake, (2) wading bird density was higher at L-Lake than at the other two reservoirs, (3) wading birds represented a higher proportion of the total avian community at L-Lake than at the other two, older reservoirs, and (4) wading birds at L-Lake used planted portions of the shoreline more than unplanted portions. We suggest that the inter-reservoir differences we observed represent a trophic upsurge (sensu O'Brien, 1990) resulting from the increased availability of fishes at L-Lake compared with the two older reservoirs.Work was performed at the University of Georgia's Savannah River Ecology Laboratory, Aiken, South Carolina 29802. 相似文献
38.
Marcel Leist Stefanie Maurer Manfred Schultz Angelika Elsner Dieter Gawlik Regina Brigelius-Flohé 《Biological trace element research》1999,68(2):159-174
Cells cultivated under standard conditions were highly deficient in tocopherol, selenium, and glutathione peroxidase (GPx)
activities. We investigated whether and to what extent the addition of different selenocompounds to growth media would alter
biochemical, physiological, and pathophysiological parameters of cultured liver cells. Cellular uptake of selenium, GPx activities,
and cytoprotection were measured and compared in human hepatoma cells (HepG2). Selenite and selenocystine were Se donors of
high bioavailability (i.e., with these culture supplements, the increased Se uptake, induction of GPx isoenzymes, and protection
of treated cells from lipid hydroperoxides were well correlated). In contrast, selenium from selenomethionine was incorporated
into cellular proteins but had no effect on GPx activities or cytoprotection. The data show that not all selenium donors provide
selenium, which is bioactivated to act as antioxidant. Thus, cellular selenium content, in general, did not correlate with
cytoprotective activity of this trace element. However, cellular GPx activities at different times, with different concentrations,
and with different Se donors always correlated with protection from lipid hydroperoxides and may, thus, represent a more reliable
parameter to define adequate Se supply. 相似文献
39.
Stomatal density, anatomy and nutrient concentrations of Scots pine needles are affected by elevated CO2 and temperature 总被引:1,自引:0,他引:1
EEVA-MARIA LUOMALA KAISA LAITINEN SIRKKA SUTINEN SEPPO KELLOMÄKI & ELINA VAPAAVUORI 《Plant, cell & environment》2005,28(6):733-749
Stomatal density, anatomy and nutrient concentrations of Scots pine (Pinus sylvestris L.) needles were studied during 3 years of growth at elevated CO2 (693 ± 30 µmol mol−1), at elevated temperature (ambient +2·8–6·2 °C depending on the time of the year) and in a combination of elevated CO2 and temperature in closed-top chambers. The treatments were started in August 1996. At elevated temperature, the needles that were grown in the first year (i.e. the 1997 cohort) were thinner, had thinner mesophyll in the abaxial side, thinner vascular cylinder and lower stomatal density than those grown at ambient temperature. The proportion of mesophyll area occupied by vascular cylinder or intercellular spaces were not changed. Lower stomatal density apparently did not lead to decreased use of water, as these needles had higher concentrations of less mobile nutrients (Ca, Mg, B, Zn and Mn), which could indicate increased total transpiration. In the 1997 and 1998 cohorts, elevation of temperature decreased concentrations of N, P, K, S and Cu. In the 1999 cohort, contradictory, higher concentrations of N and S at elevated temperature may be related to increased nutrient mineralization in the soil. Elevation of CO2 did not affect stomatal density, needle thickness, thickness of epidermis or hypodermis, vascular cylinder or intercellular spaces. Concentrations of N, P, S and Cu decreased at elevated CO2. Reductions were transient and most distinct in the 1997 cohort. The effects of CO2 and temperature were in some cases interactive, which meant that in the combined treatment stomatal density decreased less than at elevated temperature, and concentrations of nutrients decreased less than expected on the basis of separate treatments, whereas the thickness of the epidermis and hypodermis decreased more than in the separate treatments. In conclusion, alterations in the anatomy and stomatal density of Scots pine needles were more distinct at elevated temperature than at elevated CO2. Both elevated CO2 and temperature-induced changes in nutrient concentrations that partly corresponded to the biochemical and photosynthetic alterations in the same cohorts ( Luomala et al. Plant, Cell and Environment 26, 645–660, 2003 ) Reductions in nutrient concentrations and alterations in the anatomy were transient and more evident in the needle cohort that was grown in the first treatment year. 相似文献
40.
KATARIINA ROININEN LAURENCE FILLION DAVID KILCAST LIISA LÄHTEENMÄKI 《Journal of sensory studies》2003,18(6):437-451
The aim of the study was to determine how those texture attributes that elderly people find difficult to eat are related to their preferences for different modifications of carrot textures. This study was conducted with same methods in Finland and in the United Kingdom (UK). Trained sensory panels in both countries described sensory profiles of a range of carrot samples with same glossary of texture terms. The texture of carrot samples was manipulated using different preparation and cooking methods. Based on the Principal Component Analysis (PCA), boiled and puréed samples were perceived as soft, wet, pulpy and smooth, whereas raw samples were dry, brittle, rough, crispy and crunchy. Two age groups were used for the consumer tests: a young adult group aged 23 to 40 years, mean 32 (Finland) and 33 (UK) and an elderly group aged over 60 years, mean 75 (Finland) and 76 (UK). Both the elderly and young adult respondents considered samples as difficult to eat if they needed a long chewing time, were crunchy, hard, brittle, dry, rough or sharp, such as raw slices and coarsely grated samples. On the other hand, slimy, wet, smooth, soft and pulpy samples, such as boiled carrots and purée, were considered as easy-to-eat. The young adults liked more difficult textures such as rough, crispy, crunchy and hard than did the elderly respondents, but the easiest textures were not liked by either age group. Subjects with dental deficiencies liked easier textures more than those fully dentate. 相似文献