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81.
Tao Cong-Qi Ding Yi Zhao Yang-Jie Cui Heng-Lin 《Journal of microbiology (Seoul, Korea)》2020,58(2):105-112
Journal of Microbiology - Two halophilic archaeal strains, SHR37T and NEN6, were isolated from salt lakes located in the Tibet and Xinjiang regions of China. The two strains were found to form a... 相似文献
82.
Du Xuemei Fang Ting Liu Yan Huang Liying Wang Xiaoli Zhang Jie Cui Yangbo Zang Maosen Wang Guoying Fu Junjie Liu Yunjun 《In vitro cellular & developmental biology. Plant》2020,56(2):159-168
In Vitro Cellular & Developmental Biology - Plant - Callus induction in plants is similar to pluripotent stem cell induction in animals and can incite global changes in gene expression.... 相似文献
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84.
Ning Jiang Jun Cui Xinxin Hou Guanglei Yang Yu Xiao Lu Han Jun Meng Yushi Luan 《The Plant journal : for cell and molecular biology》2020,103(4):1561-1574
Long non‐coding RNAs (lncRNAs) are involved in the resistance of plants to infection by pathogens via interactions with microRNAs (miRNAs). Long non‐coding RNAs are cleaved by miRNAs to produce phased small interfering RNAs (phasiRNAs), which, as competing endogenous RNAs (ceRNAs), function as decoys for mature miRNAs, thus inhibiting their expression, and contain pre‐miRNA sequences to produce mature miRNAs. However, whether lncRNAs and miRNAs mediate other molecular mechanisms during plant resistance to pathogens is unknown. In this study, as a positive regulator, Sl‐lncRNA15492 from tomato (Solanum lycopersicum Zaofen No. 2) plants affected tomato resistance to Phytophthora infestans. Gain‐ and loss‐of‐function experiments and RNA ligase‐mediated 5′‐amplification of cDNA ends (RLM‐5′ RACE) also revealed that Sl‐miR482a was negatively involved in tomato resistance by targeting Sl‐NBS‐LRR genes and that silencing of Sl‐NBS‐LRR1 decreased tomato resistance. Sl‐lncRNA15492 inhibited the expression of mature Sl‐miR482a, whose precursor was located within the antisense sequence of Sl‐lncRNA15492. Further degradome analysis and additional RLM‐5′ RACE experiments verified that mature Sl‐miR482a could also cleave Sl‐lncRNA15492. These results provide a mechanism by which lncRNAs might inhibit precursor miRNA expression through antisense strands of lncRNAs, and demonstrate that Sl‐lncRNA15492 and Sl‐miR482a mutually inhibit the maintenance of Sl‐NBS‐LRR1 homeostasis during tomato resistance to P. infestans. 相似文献
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86.
The regulation of insulin on depression and depression‐like behaviour has been widely reported. Insulin and activation of its receptor can promote learning and memory, affect the hypothalamic‐pituitary‐adrenal axis (HPA) balance, regulate the secretion of neurotrophic factors and neurotransmitters, interact with gastrointestinal microbiome, exert neuroprotective effects and have an impact on depression. However, the role of insulin on depression remains largely unclear. Therefore, in this review, we summarized the potential role of insulin on depression. It may provide new insight for clarifying role of insulin on the pathogenesis of depression. 相似文献
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耐盐碱促生菌的筛选及性能 总被引:1,自引:0,他引:1
盐分是影响作物生长最重要的因素,使用能促进植物生长的耐盐碱促生菌减轻盐胁迫引起的损害是一种农业上的有效方法。文中从盐碱地筛选得到7株耐盐细菌,并考察筛选菌株的产胞外聚合物(EPS)能力、降碱能力和产吲哚-3-乙酸(IAA)能力。经综合评价选出1株优势菌株DB01,菌株DB01产EPS能力为0.21 g/g,降碱能力为8.7%,产IAA的能力为8.97 mg/L。菌株经16S rRNA鉴定为海水盐单胞菌Halomonas aquamarina,并且有抑制香蕉枯萎病、番茄早疫病、大豆疫霉病、小麦纹枯病病原菌的能力,同时能够在盐胁迫下促进小麦幼苗的发芽率和根长。海水盐单胞菌Halomonas aquamarina DB01可为土壤微生物资源开发利用和盐碱地改良提供理论依据。 相似文献
89.
Yi-Kun Zhou Ling-Su Zhu Hua-Ming Huang Sheng-Jie Cui Ting Zhang Yan-Heng Zhou Rui-Li Yang 《World journal of stem cells》2020,12(12):1623-1639
BACKGROUNDAutoimmune hepatitis is a serious autoimmune liver disease that threatens human health worldwide, which emphasizes the urgent need to identify novel treatments. Stem cells from human exfoliated deciduous teeth (SHED), which are easy to obtain in a non-invasive manner, show pronounced proliferative and immunomodulatory capacities.AIMTo investigate the protective effects of SHED on concanavalin A (ConA)-induced hepatitis in mice, and to elucidate the associated regulatory mechanisms.METHODSWe used a ConA-induced acute hepatitis mouse model and an in vitro co-culture system to study the protective effects of SHED on ConA-induced autoimmune hepatitis, as well as the associated underlying mechanisms.RESULTSSHED infusion could prevent aberrant histopathological liver architecture caused by ConA-induced infiltration of CD3+, CD4+, tumor necrosis-alpha+, and interferon-gamma+ inflammatory cells. Alanine aminotransferase and aspartate aminotransferase were significantly elevated in hepatitis mice. SHED infusion could therefore block ConA-induced alanine aminotransferase and aspartate aminotransferase elevations. Mechanistically, ConA upregulated tumor necrosis-alpha and interferon-gamma expression, which was activated by the nuclear factor-kappa B pathway to induce hepatocyte apoptosis, resulting in acute liver injury. SHED administration protected hepatocytes from ConA-induced apoptosis. CONCLUSIONSHED alleviates ConA-induced acute liver injury via inhibition of hepatocyte apoptosis mediated by the nuclear factor-kappa B pathway. Our findings could provide a potential treatment strategy for hepatitis. 相似文献
90.
Xiaohan Sun Feng Wang Rong Cui Xiao Liu Xiangxiang Li Jibin Dong Lu Sun Siqi Qin Renqing Wang Peiming Zheng Hui Wang 《Ecology and evolution》2020,10(12):5270-5280
Vitex negundo L. var. heterophylla (Franch.) Rehder (Lamiaceae) is an important tree species for soil and water conservation, yet the reproductive ecology of this species remains to be elucidated. To investigate the reproductive traits of V. negundo var. heterophylla, the phenology, morphological characteristics (a suite of characters was assessed: floral morphology, nectar production, pollen viability, and stigma receptivity) and mating system of this species were systematically revealed for the first time in this study. Phenological observations, morphological measurements, and nectar production analysis were conducted during anthesis. Pollen viability and stigma receptivity at different flowering stages were measured by biochemical methods. Finally, genetic analysis based on SSR markers was used to reveal the mating system; outcrossing index and pollen‐ovule ratio were also calculated to help analysis. V. negundo var. heterophylla showed several obvious characteristics of outcrossing, such as abundant and attractive flowers, secreting nectar, and emitting scent. In addition, mechanisms such as homogamy and a short anther‐stigma distance that can promote self‐fertilization were also identified in this species. The coexistence of selfing and outcrossing characteristics demonstrates a predominantly outcrossed mixed mating system (outcrossing rate, t = 95%). The scientific information provided by this study may contribute to conservation of V. negundo var. heterophylla from a reproductive perspective. 相似文献