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Most behaviors are conditional upon successful navigation of the environment, which depends upon distance perception learned over repeated trials. Unfortunately, we understand little about how learning affects distance perception–especially in the most common human navigational scenario, that of adult navigation in familiar environments. Further, dominant theories predict mutually exclusive effects of learning on distance perception, especially when the risks or costs of navigation differ. We tested these competing predictions in four experiments in which we also presented evolutionarily relevant navigation costs. Methods included within- and between-subjects comparisons and longitudinal designs in laboratory and real-world settings. Data suggested that adult distance estimation rapidly reflects evolutionarily relevant navigation costs and repeated exposure does little to change this. Human distance perception may have evolved to reflect navigation costs quickly and reliably in order to provide a stable signal to other behaviors and with little regard for objective accuracy. 相似文献
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Resting-cell suspensions of Serratia marcescens were able to convert, quantitatively, 0.3% vanillin to vanillic acid. The vanillic acid-producing activity reached a maximum after 28 h of incubation with 0.01% vanillin as an inducer. 相似文献
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Expression of alkaline phosphatase in murine B lymphocytes. Correlation with B cell differentiation into Ig secretion 总被引:2,自引:0,他引:2
C Marquez M L Toribio M A Marcos A de la Hera A Barcena L Pezzi C Martinez 《Journal of immunology (Baltimore, Md. : 1950)》1989,142(9):3187-3192
Alkaline phosphatases (ALPase) (orthophosphoric-monoester phosphohydrolase, EC 3.1.3.1) are implicated in many biologic phenomena including ossification and differentiation of human neutrophils and choriocarcinoma cells. Another trait, demonstrated by microinjection into Xenopus oocytes, is their ability to block the first mitotic division. Previous work in our laboratory has established that ALPase is also present on murine B lymphocytes activated by either polyclonal mitogens or Th cells. We have now characterized the ALPase present on murine B cells as belonging to the liver-bone-kidney isoenzyme and found it to be implicated in B cell differentiation into antibody secretion. Thus, B cell proliferative responses, elicited either by high concentrations of rabbit anti-IgM antibodies or by LPS in the presence of PMA, are characterized by the lack of both antibody secretion and expression of ALPase activity. In contrast, B cells stimulated to differentiate into Ig-secreting cells by B cell differentiation factors, nearly in the absence of a proliferative response, express high levels of ALPase activity, as did those that were LPS-stimulated. These data showing the association of the ALPase expression with the process of B cell differentiation into antibody-secreting cells are discussed in the context of the possible role that phosphorylation-dephosphorylation mechanism may play in controlling the growth/differentiation rate in the B cell lineage. 相似文献
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P. Hernández R. de la Rosa L. Rallo A. Martín G. Dorado 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》2001,102(6-7):1082-1087
When developing SCARs by sequencing RAPD markers useful for olive variety identification, one RAPD sequence of 407 bp has
been identified that shows significant DNA homology with more than 160 retrotransposon-like sequences. A generally coherent
phylogenetic tree has been constructed based on the homologous retrotransposon-like sequences, reflecting genetic distances
in 35 species belonging to eight kingdoms. The implications of this finding in the development of SCAR markers are discussed.
In addition, specific oligonucleotide primers have been developed to amplify the DNA region and have a practical application
as an internal amplification control in SCAR-based multiplexed PCRs. To our knowledge, this is the first report of a retrotransposon-like
element in olive.
Received: 31 July 2000 / Accepted: 22 September 2000 相似文献