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THE acute inflammatory response following many types of tissue injury involves principally an increase in vascular permeability and the migration of leukocytes towards the inflammatory focus1. Although the complement system is known to be involved in the acute inflammatory response to allergic causes2,3, the nature of non-immunologically induced inflammation, however, is still rather obscure. We recently reported that prostaglandin E1 (PGE1) increased vascular permeability in rat skin and rat cremasteric muscle to a degree and in a pattern, not unlike that produced by histamine or serotonin4. 相似文献
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M GABOR 《Acta physiologica Hungarica》1952,3(3-4):591-594
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PROSTAGLANDINS have been suggested as mediators of inflammatory reactions because they increase vascular permeability1,2, are found in inflammatory exudates3, are released during antigen-antibody reactions4 and have leucotactic properties5. For this reason and because lysosomes have been assigned an important role in the pathogenesis of diverse tissue injury reactions6, we have studied the effect of prostaglandins on lysosomal fragility. 相似文献
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GABOR J. BETHLENFALVAY SALAH S. ABU-SHAKRA KATHLEEN FISHBECK DONALD A. PHILLIPS 《Physiologia plantarum》1978,43(1):31-34
The effect on nitrogen fixation of excising leaves or pods in pea (Pisum sativum L. cv. Alaska) was determined over a 60-day period. Flower buds or their subtending leaves were removed, and C2H2 reduction, H2 evolution and N accumulation were measured at weekly intervals. Highest percentage nitrogen content in all treatments coincided with time of maximal C2H2-reduction rates. Nitrogen fixation, calculated from C2H2 reduction and H2- evolution data, was significantly lower in the partially defoliated and generally higher in the depodded plants than in the controls. Total N accumulation was greatest in the depodded plants and least in the defoliated ones. Percentage nitrogen content and N2-fixation rates in the depodded plants were maximized approximately 10 days later than in the defoliated or control plants. The absolute rates of C2H2 reduction and H2 evolution were significantly altered by plant organ removal, but the relative rates were proportional. As a result the ratios of H2/C2H4 production and the related relative efficiency of N2 fixation in the treatments were not significantly different from the controls. 相似文献
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