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Posterior tibial tendinopathy associated with matrix metalloproteinase 13 promoter genotype and haplotype 下载免费PDF全文
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MM El-Shazly El Elzayat IIA El-Sebeay YA Edmardash MM Soliman 《African Journal of Aquatic Science》2016,41(3):289-296
Manzala Lake, as one of the main Egyptian wetland ecosystems, is facing risks of pollution. An in vitro cytotoxicity test using a mammalian cell line was employed to determine the toxicity of multiple pollutants in the water and Tilapia zillii fish sampled from the lake. The concentrations of seven polychlorinated dibenzo-p-dioxins and ten polychlorinated dibenzofurans were investigated in water and muscle of the fish in 2014. Cytotoxicity testing showed that the percentage inhibition of cell viability in the studied sites ranged between 56.16% and 83.22%. Dioxin analysis indicated that the average concentrations of 1,2,3,4,6,7,8,9-octachlorodibenzo-p-dioxin, 1,2,3,4,7,8-hexachlorodibenzofuran, 1,2,3,4,6,7,8-heptachlorodibenzofuran and 1,2,3,4,6,7,8,9-octachlorodibenzofuran were higher than the toxic equivalence quotients (TEQs) set by the World Health Organization (WHO) in all water and fish muscle samples; however, the average concentration of 2,3,7,8-tetrachlorodibenzofuran was higher only in fish muscle samples. The bioaccumulation factor (BAF) ranged dramatically between 2 and 58.5 for the detected dioxins. Adverse human health effects through the consumption of fish are not expected, because dioxin levels in fish muscle are deemed safe for human consumption. Implementation of a strategic multidisciplinary action plan is strongly recommended to sustain this delta wetland ecosystem. 相似文献
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Experiments evaluate the effects of two tagging/marking techniques on Osteochilus hasselti C. & V. at Subang Reservoir, Malaysia. Based on suitability, the staple tag and fluorescent pigment were used in short-term studies on population estimates and movement of the fish respectively. The discrete population of Osteochilus hasselti at one sampling station, Garong Panjang, is 1709 individuals during the survey period. The marked fish exhibit limited movement. The average distance moved is 15 meters, with most fish heading upstream. The average maximum dimension of the movement range is = 46 ± 8 meters at night and = 28 ± 5 meters in the day. 相似文献
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Summary It has been shown by means of Bentley'sin vitro preparation of the isolated urinary bladder of the toad,Bufo marinus paracnemis Lutz, that bradykinin reversibly inhibited the increase brought about by vasopressin on the permeability to water of the
toad bladder. The increased hydro-osmotic response of the bladder to oxytocin was also inhibited by the kinin. The effect
on water permeability was observed when bradykinin was added either to the serosal Ringer's solution or to the mucosal solution.
The addition of bradykinin alone did not alter the basal osmotic water transfer across the bladder. In this context, bradykinin
acted as a competitive antagonist of vasopressin (and oxytocin). Although lacking intrinsic activity, bradykinin exhibited
affinity for receptor sites that are also common to the neurohypophysial hormones, causing a parallel shift of the log-dose/response
curve for vasopressin without changing the maximal responses. The effects of other kinins (namely kallidin, eledoisin and
physalaemin) on the toad bladder were also tested. Each of these drugs alone did not change the basal water flux across the
bladder wall. Like bradykinin, these peptides inhibited the increase in water permeability evoked by vasopressin and oxytocin
in the bladder. In view of the importance of neurohypophysial hormones and their target tissues to the osmotic homeostasis
of amphibians, and the observation of antagonism between the kinins and the pituitary hormones coupled to the abundance of
kinins in the amphibian organism, particularly in the skin and urinary bladder, teleological reasoning predicts a physiological
role for the kinins, possibly functioning to dampen excesses and oscillations in membrane permeability that could occur in
face of a constant and variable secretion of neurohypophysial hormone, thus adding to the homeostatic response of the amphibian
organism. 相似文献
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Sans résuméI. Analyse électrocapillaire des matières colorantes. Rev. gén. Mat. Col. 1926 Vol. 30 pp 34–45II. Phénomènes électrocapillaires et le problème du cancer. Arch. Med. Exper. 1926 Vol. I p 381III. Phénomènes électrocapillaires et l'antagonismes microbiens. Bol. Istituto Sier. Milano 1927 Vol. VI p 313. 相似文献