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41.
Calcium sulfoaluminate‐based cements (CSA) are proposed as a cement alternative with a low carbon footprint. The nature of CSA makes the manufacturing process to require lower temperature, less fuel, and less calcite. However, it requires aluminum oxide, Al2O3, which would be originated from bauxite and bauxite‐derived wastes, and sulfur, coming from calcium sulfate or elemental sulfur. An eco‐efficiency assessment of CSA cements, benchmarked against the conventional Portland cement, has been performed following the principles of ISO 14045 on eco‐efficiency for a total of 240 CSA clinker production scenarios. The eco‐efficiency indicator relates an environmental indicator with a product system value indicator, and it is calculated for each of the studied parameters: bauxite geographical origin, the fuel used for clinkering, the source of sulfur, and the composition of the clinker. Eco‐efficiency results show a strong dependence on the origin of bauxite, while other parameters, as the fuel used, its content in sulfur, or the supply of other raw materials, are of less importance. The most eco‐efficient solutions are those with certain closeness to bauxite sources. To achieve global solutions, that is, cement‐making based on CSA independently of the origin of the raw materials, the amount of bauxite needs to be minimized and CSA composition restricted.  相似文献   
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The International Journal of Life Cycle Assessment - Given the increasing importance of political decision-making to reduce emission targets, the main purpose of the current paper is to identify...  相似文献   
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Despite early reperfusion, patients with ST segment elevation myocardial infarction (STEMI) may present large myocardial necrosis and significant impairment of ventricular function. The present study aimed to evaluate the role of subtypes of B lymphocytes and related cytokines in the infarcted mass and left ventricular ejection fraction obtained by cardiac magnetic resonance imaging performed after 30 days of STEMI. This prospective study included 120 subjects with STEMI submitted to pharmacoinvasive strategy. Blood samples were collected in subjects in the first (D1) and 30th (D30) days post STEMI. The amount of CD11b+ B1 lymphocytes (cells/ml) at D1 were related to the infarcted mass (rho = 0.43; P=0.033), measured by cardiac MRI at D30. These B1 cells were associated with CD4+ T lymphocytes at D1 and D30, while B2 classic lymphocytes at day 30 were related to left ventricular ejection fraction (LVEF). Higher titers of circulating IL-4 and IL-10 were observed at D30 versus D1 (P=0.013 and P<0.001, respectively). Titers of IL-6 at D1 were associated with infarcted mass (rho = 0.41, P<0.001) and inversely related to LVEF (rho = −0.38, P<0.001). After multiple linear regression analysis, high-sensitivity troponin T and IL-6 collected at day 1 were independent predictors of infarcted mass and, at day 30, only HDL-C. Regarding LVEF, high-sensitivity troponin T and high-sensitivity C-reactive protein were independent predictors at day 1, and B2 classic lymphocytes, at day 30. In subjects with STEMI, despite early reperfusion, the amount of infarcted mass and ventricular performance were related to inflammatory responses triggered by circulating B lymphocytes.  相似文献   
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Probiotics and Antimicrobial Proteins - Bacterial spores of the genus Bacillus are being evaluated as adjuvant molecules capable of improving the immune response to vaccines. In this study, we...  相似文献   
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Abstract

When designing any rehabilitation, sportswear or exoskeleton device the mechanical behaviour of the body segment must be known, specifically the skin, because an excessive tissue strain may lead to ulceration and bedsores. To date, it is not known if the kinematic variability between subjects have an effect on the skin strain field, and therefore, in the design and manufacturing of rehabilitation products, such as orthoses. Several studies have analysed the skin deformation during human motion, nevertheless, the comparison between the skin strain field in different subjects during normal or pathological gait has not been reported yet. This work presents a comparison of skin strain analysis for different gait patterns to study the differences between people and, specifically, if it is possible to standardize the orthotic design between subjects with the same gait disorder. Moreover, the areas with relatively minimum strain during the ankle-foot motion are compared to improve the design of structural parts of rehabilitation devices. In this case, a validated 3D digital image correlation system has been used for this purpose combined with strain ellipse theory. The results demonstrate variations in the skin strain field between subjects with the same pathology and similarities between subjects with normal gait. However, more studies and experiments are necessaries to validate this hypothesis and also to test it between different gait pathologies.  相似文献   
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