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871.
Diversification with gene flow and niche divergence in a lizard species along the South American “diagonal of open formations”
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872.
Elisa Castañeda Santa Cruz Flávia da Silva Zandonadi Wagner Fontes Alessandra Sussulini 《Biochimica et Biophysica Acta - Proteins and Proteomics》2021,1869(8):140657
A better understanding of the proteome profile after bipolar disorder (BD) and schizophrenia (SCZ) treatment, besides monitoring disease progression, may assist on the development of novel therapeutic strategies with the ability to reduce or control possible side effects. In this pilot study, proteomics analysis employing nano liquid chromatography coupled to mass spectrometry (nLC-MS) and bioinformatic tools were applied to identify differentially abundant proteins in serum of treated BD and SCZ patients. In total, 10 BD patients, 10 SCZ patients, and 14 healthy controls (HC) were included in this study. 24 serum proteins were significantly altered (p < 0.05) in BD and SCZ treated patients and, considering log2FC > 0.58, 8 proteins presented lower abundance in the BD group, while 7 proteins presented higher abundance and 2 lower abundance in SCZ group when compared against HC. Bioinformatics analysis based on these 24 proteins indicated two main altered pathways previously described in the literature; furthermore, it revealed that opposite abundances of the complement and coagulation cascades were the most significant biological processes involved in these pathologies. Moreover, we describe disease-related proteins and pathways associations suggesting the necessity of clinical follow-up improvement besides treatment, as a precaution or safety measure, along with the disease progression. Further biological validation and investigations are required to define whether there is a correlation between complement and coagulation cascade expression for BD and SCZ and cardiovascular diseases. 相似文献
873.
Valdecy Aparecida Rocha da Cruz Flávio Schramm Schenkel Rodrigo Pelicioni Savegnago Natalia Vinhal Grupioni Nedenia Bonvino Stafuzza Mehdi Sargolzaei Adriana Mércia Guaratini Ibelli Jane de Oliveira Peixoto M?nica Corrêa Ledur Danísio Prado Munari 《PloS one》2015,10(8)
Apolipoprotein B (APOB) and Adiponectin Receptor 1 (ADIPOR1) are related to the regulation of feed intake, fat metabolism and protein deposition and are candidate genes for genomic studies in birds. In this study, associations of two single nucleotide polymorphisms (SNPs) g.102
A>T (APOB) and g.729
C>T (ADIPOR1) with carcass, bone integrity and performance traits in broilers were investigated. Genotyping was performed on a paternal line of 1,454 broilers. The SNP detection was carried out by PCR-RFLP technique using the restriction enzymes HhaI for the SNP g.729
C>T and MslI for the SNP g.102
A>T. The association analyses of the two SNPs with 85 traits were performed using the restricted maximum likelihood (REML) and Generalized Quasi-Likelihood Score (GQLS) methods. For REML the model included the random additive genetic effect of animal and fixed effects of sex, hatch and SNP genotypes. In the GQLS method, a logistic regression was used to associate the genotypes with phenotypes adjusted for fixed effects of sex and hatch. The SNP g.729
C>T in the ADIPOR1 gene was associated with thickness of the femur and breast skin yield. Thus, the ADIPOR1 gene seems implicated in the metabolism and/or fat deposition and bone integrity in broilers. 相似文献
874.
875.
Longo Pedro Augusto dos Santos Mansur Karine Ferreira Ribeiro Siqueira Silvana Gomes Leite Passos Flávio Dias Leite Fosca Pedini Pereira 《Aquatic Ecology》2021,55(2):623-646
Aquatic Ecology - Anthropogenic impacts cause habitat losses and reduce biodiversity in marine coastal habitats. Coastal macroalgae beds and their associate invertebrates are highly susceptible to... 相似文献
876.
Biodiversity of diazotrophic bacteria within the soil, root and stem of field-grown maize 总被引:1,自引:0,他引:1
Luiz Fernando W. Roesch Flávio A. O. Camargo Fátima M. Bento Eric W. Triplett 《Plant and Soil》2008,302(1-2):91-104
Recent studies suggest a high diversity of diazotrophic bacteria in maize. However, none of these works have been based on
a sufficient number of samples to provide reasonable quantitative estimates of diazotrophic bacterial diversity. Here we present
the use of molecular tools and statistical inference to assess diazotrophic bacterial diversity within rhizosphere soils,
roots and stems of field grown maize. DNA was isolated from the latter collected from six maize growing regions within the
southern most state in Brazil, Rio Grande do Sul. Using conserved primers, nifH Cluster I gene fragments were amplified from each of the three zones, and the products cloned and sequenced. The majority
of the sequences were classified within the Proteobacteria with the α-proteobacteria and β-proteobacteria being the most abundant in the rhizosphere soil and stem samples. The γ-proteobacteria were most abundant in rhizosphere soils, less so in roots, and least in the stem samples. According to three different diversity
measures, the rhizosphere soil samples possessed greater diazotrophic bacterial diversity than the roots and stems of the
maize plants. Only two genera, Azospirillum and Azotobacter, were found in virtually all samples at an abundance of over 1% of the total nifH sequences obtained. Other genera were largely restricted to soil (Methylocystis, Beijerinckia, Geobacter, Rhodovulum, Methylobacterium, Gluconacetobacter, Methylocella, and Delftia), roots (Dechloromonas), or stems (Methylosinus, Raoultella, and Rhizobium). Three genera, Herbaspirillum, Ideonella, and Klebsiella, appeared to dominate in the interior of the plant but were much rarer in soil. 相似文献
877.
878.
879.
Ruzon FI de Paula SB Kanoshiki RL Pereira-Santos J Kerbauy G Kobayashi RK Yamauchi LM Perugini MR Yamada-Ogatta SF 《Journal of microbiology (Seoul, Korea)》2010,48(6):814-821
Enterococcus faecium, especially those showing multidrug resistance, has emerged as a significant cause of healthcare-associated infections worldwide.
However, relatively little is known about the virulence and pathogenesis of this species. The aim of this study was to determine
the occurrence of four putative virulence determinants of E. faecium and to correlate them with phenotypic traits. Using forty E. faecium vanA-type isolates from hospitalized patients and their environmental vicinity, we determined the following: the antimicrobial
susceptibility profile, occurrence of the genes cylA, efaA, esp, and gelE, hemolytic and gelatinase activities, capacity to form biofilm and in vitro adhesion to epithelial cells. All isolates were shown to be resistant to vancomycin and teicoplanin, as well as to two or
more other antimicrobials. All isolates harbored at least one putative virulence marker, and the prevalence was as follows:
esp, 87.5%; efaA, 82.5%; gelE, 70%; and cylA, 65%. The presence of 4 genes was observed in 32.5% isolates. The presence of the efaA was associated with the presence of esp, regardless of the source of the isolates. A positive association with the presence of cylA and hemolytic activity in the sheep blood agar assay was observed. No association was found for gelE and gelatinase production in the agar plate assay, for efaA and LLC-MK2 cell adhesion, and for esp and biofilm formation on polystyrene surface. These results show the presence of putative virulence genes in multiple antimicrobial
resistant E. faecium isolates from different sources in a hospital setting. 相似文献
880.
Martina Flörchinger Julius Braun Katrin Böhning-Gaese H. Martin Schaefer 《Oecologia》2010,164(1):151-161
Seed dispersal by animals is an important ecological process shaping plant regeneration. In general, seed dispersers are highly
variable and often opportunistic in their fruit choice. Despite much research, the factors that can explain patterns of fruit
consumption among different animal groups remain contentious. Here, we analysed the interactions between 81 animal species
feeding on the fruits of 30 plant species in Kakamega Forest, Kenya, during 840 h of observations. Our aim was to determine
whether plant characteristics, fruit morphology, fruit colours and/or fruit compounds such as water, sugar, phenols and tannins
explained the relative importance of fruit consumption by the two most important consumer groups, primates and birds. We found
significant differences in fruit choice between both groups. Primates fed on larger fruits and on higher trees that had larger
fruit crops, whereas birds were observed feeding on smaller fruits and on smaller plants producing fewer fruits. Fruit colours
did not differ between fruits consumed by primates and those consumed by birds. However, differences in the fruit choice among
frugivorous birds were associated with differences in fruit colours. Smaller plants with smaller fruits produced red fruits
which contrasted strongly with the background; these fruits were dispersed by a distinct set of bird species. The contents
of water, sugar, phenols and tannins did not differ between fruits eaten by primates and those eaten by birds. Some phylogenetic
patterns were apparent; primates fed preferentially on a phylogenetically restricted subsample of large plants with large
fruits of the subclass Rosidae. We discuss why the observed primate dispersal syndrome is most likely explained by a process
of ecological fitting. 相似文献