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111.
Leonel da Silveira Lobo Sternberg Su Yean Teh Sharon M. L. Ewe Fernando Miralles-Wilhelm Donald L. DeAngelis 《Ecosystems》2007,10(4):648-660
A
bstract
The boundaries between mangroves and freshwater hammocks in coastal ecotones of South Florida are sharp. Further, previous
studies indicate that there is a discontinuity in plant predawn water potentials, with woody plants either showing predawn
water potentials reflecting exposure to saline water or exposure to freshwater. This abrupt concurrent change in community
type and plant water status suggests that there might be feedback dynamics between vegetation and salinity. A model examining
the salinity of the aerated zone of soil overlying a saline body of water, known as the vadose layer, as a function of precipitation,
evaporation and plant water uptake is presented here. The model predicts that mixtures of saline and freshwater vegetative
species represent unstable states. Depending on the initial vegetation composition, subsequent vegetative change will lead
either to patches of mangrove coverage having a high salinity vadose zone or to freshwater hammock coverage having a low salinity
vadose zone. Complete or nearly complete coverage by either freshwater or saltwater vegetation represents two stable steady-state
points. This model can explain many of the previous observations of vegetation patterns in coastal South Florida as well as
observations on the dynamics of vegetation shifts caused by sea level rise and climate change. 相似文献
112.
Diversity of Helicobacter pylori cagA and vacA genes in Costa Rica: its relationship with atrophic gastritis and gastric cancer 总被引:3,自引:0,他引:3
Con SA Takeuchi H Valerín AL Con-Wong R Con-Chin GR Con-Chin VG Nishioka M Mena F Brenes F Yasuda N Araki K Sugiura T 《Helicobacter》2007,12(5):547-552
BACKGROUND: Associations between Helicobacter pylori gene diversity and gastric cancer have not been reported on in Costa Rica, despite its being one of the countries with the highest gastric cancer incidence and mortality rates in the world. The aim of this study was to determine the prevalence of H. pylori cagA and vacA genes and investigate whether it could be correlated with atrophic gastritis (AG) and gastric cancer (GC) in Costa Rica. MATERIALS AND METHODS: Genomic DNAs from isolates of 104 patients classified into two groups: non-atrophic gastritis group (n = 68) and atrophic gastritis group (n = 36), were subjected to PCR-based genotyping of cagA and vacA genes and their correlation with clinical outcome was investigated. Total DNA extractions from gastric tissues of 25 H. pylori-infected gastric cancer patients were utilized for comparative purposes. RESULTS: The presence of cagA (75.3%), vacA s1b (75.3%), and vacA m1 (74.2%) was detected, and colonization by strains with different vacA genotypes in the same stomach was found in 9.7% of the patients. Age- and sex-adjusted vacA s1b and vacA m1 were associated with GC while only vacA m1 was significantly associated with AG. A tendency for association between cagA and vacA s1b, and AG was reported. CONCLUSIONS: The prevalence status of the cagA and vacA (s1/m1) genes in Costa Rica seems to fall between that found in European/North American and East Asian countries, and both cagA and vacA seem to have clinical relevance in this country. 相似文献
113.
Timmers LF Ducati RG Sánchez-Quitian ZA Basso LA Santos DS de Azevedo WF 《Journal of molecular modeling》2012,18(2):467-479
Cytidine Deaminase (CD) is an evolutionarily conserved enzyme that participates in the pyrimidine salvage pathway recycling cytidine and deoxycytidine into uridine and deoxyuridine, respectively. Here, our goal is to apply computational techniques in the pursuit of potential inhibitors of Mycobacterium tuberculosis CD (MtCDA) enzyme activity. Molecular docking simulation was applied to find the possible hit compounds. Molecular dynamics simulations were also carried out to investigate the physically relevant motions involved in the protein-ligand recognition process, aiming at providing estimates for free energy of binding. The proposed approach was capable of identifying a potential inhibitor, which was experimentally confirmed by IC50 evaluation. Our findings open up the possibility to extend this protocol to different databases in order to find new potential inhibitors for promising targets based on a rational drug design process. 相似文献
114.
Martin R. Ciancio Mariela C. Castro Fernando C. Galliari Alfredo A. Carlini Robert J. Asher 《Journal of Mammalian Evolution》2012,19(1):1-8
Late eruption of the permanent dentition was recently proposed as a shared anatomical feature of endemic African mammals (Afrotheria),
with anecdotal reports indicating that it is also present in dasypodids (armadillos). In order to clarify this question, and
address the possiblity that late eruption is shared by afrotherians and dasypodids, we quantified the eruption of permanent
teeth in Dasypus, focusing on growth series of D. hybridus and D. novemcinctus. This genus is the only known xenarthran that retains two functional generations of teeth. Its adult dentition typically
consists of eight upper and eight lower ever-growing (or euhypsodont) molariforms, with no premaxillary teeth. All but the
posterior-most tooth are replaced, consistent with the identification of a single molar locus in each series. Comparison of
dental replacement and skull metrics reveals that most specimens reach adult size with none or few erupted permanent teeth.
This pattern of growth occurring prior to the full eruption of the dentition is similar to that observed in most afrotherians.
The condition observed in Dasypus and many afrotherians differs from that of most other mammals, in which the permanent dentition erupts during (not after)
growth, and is complete at or near the attainment of sexual maturity and adult body size. The suture closure sequence of basicranial
and postcranial epiphyses does not correlate well with dental eruption. The basal phylogenetic position of the taxon within
dasypodids suggests that diphyodonty and late dental replacement represent the condition of early xenarthrans. Additionally,
the inferred reduction in the number of molars to a single locus and the multiplication of premolars represent rare features
for any living mammal, but may represent apomorphic characters for Dasypus. 相似文献
115.
Fernando Hiraldo Borja Heredia Juan Carlos Alonso 《Ethology : formerly Zeitschrift fur Tierpsychologie》1993,93(2):117-124
Social feeding strategies of wintering red kites are analyzed in relation to age, food, roost-sites and differences from kite residents. Whereas young and adult wintering kites gathered at roost sites almost daily, adult residents did not, and immature residents only occasionally. Kites using roost sites feed more often on prey prelocated by others, while lone roosters also forage and discover food alone. After finding food, kites tend to shift to a new roost site and foraging area. Two details of the ‘information centre’ hypothesis are confirmed in our study: carcasses are unpredictably found patches, divisible between several individuals. But carcasses disappeared fast in the study area, and no increase with time in the number of birds consuming a carcass was observed, so that information transmission was unconfirmed. When kites leave the roost in groups no leader is detectable. It seems that other types of social foraging are operating, and the model best matching our results is network foraging. 相似文献
116.
117.
118.
Efflux pump‐deficient mutants as a platform to search for microbes that produce antibiotics 下载免费PDF全文
Carlos Molina‐Santiago Zulema Udaondo Abdelali Daddaoua Amalia Roca Jesús Martín Ignacio Pérez‐Victoria Fernando Reyes Juan‐Luis Ramos 《Microbial biotechnology》2015,8(4):716-725
Pseudomonas putida DOT‐T1E‐18 is a strain deficient in the major antibiotic efflux pump (TtgABC) that exhibits an overall increased susceptibility to a wide range of drugs when compared with the wild‐type strain. We used this strain as a platform to search for microbes able to produce antibiotics that inhibit growth. A collection of 2400 isolates from soil, sediments and water was generated and a drop assay developed to identify, via growth inhibition halos, strains that prevent the growth of DOT‐T1E‐18 on solid Luria–Bertani plates. In this study, 35 different isolates that produced known and unknown antibiotics were identified. The most potent inhibitor of DOT‐T1E‐18 growth was an isolate named 250J that, through multi‐locus sequence analysis, was identified as a Pseudomonas sp. strain. Culture supernatants of 250J contain four different xantholysins that prevent growth of Gram‐positive bacteria, Gram‐negative and fungi. Two of the xantholysins were produced in higher concentrations and purified. Xantholysin A was effective against Bacillus, Lysinibacillus and Rhodococcus strains, and the effect against these microbes was enhanced when used in combination with other antibiotics such as ampicillin, gentamicin and kanamycin. Xantholysin C was also efficient against Gram‐positive bacteria and showed an interesting antimicrobial effect against Pseudomonas strains, and a synergistic inhibitory effect with ampicillin, chloramphenicol and gentamicin. 相似文献
119.
The freshwater Cladocera of Sri Lanka has been revised based on the study of over 700 zooplankton samples collected from all habitat types during 1965–1980. The cladoceran fauna is represented by six families; members of the families Polyphemidae, Leptodoridae and Holopedidae are absent. The common temperate genus Daphnia is rare.Sixty-two species have been recorded from Sri Lanka. Of these, five are new records. Remarks on a few species are given with illustrations. The distribution of Cladocera in different types of habitats is discussed. The greatest species diversity was found in ponds. The Sri Lankan fauna is numerically and in species diversity typical of tropical cladoceran fauna. It resembles the southern Indian fauna very closely except for the absence in Sri Lanka of the genera Acroperus and Camptocercus. 相似文献
120.
BACKGROUND: Skin metastases from hepatocellular carcinoma (HCC) represented only 0.8% of all known cutaneous metastases in a recent large series. The most frequent site appears to be the head, but this fact has received little attention. An accurate cytologic diagnosis is extremely difficult in patients with unknown liver dysfunction. We report the cytologic features of a face metastasis from occult HCC. CASE: A 65-year-old woman presented with a mass in the right preauricular region of 2 months' duration. Her past medical history was noncontributory. Fine needle aspiration cytology was performed. Following the cytologic diagnosis, computed tomography revealed a 6-cm mass in the right lobe of the liver, portal vein thrombosis and involvement of the superior vena cava. The smears were very cellular. The most frequent pattern was trabecular with transmural endothelization. The cells had an epithelial appearance and polyhedral shape, exhibiting distinct borders. The nuclei were centrally placed, with a prominent nucleolus. The cytoplasm was granular. There were numerous atypical bare nuclei. Subsequent staining with antihepatocyte showed positivity in most tumor cells. The final diagnosis was metastatic HCC. CONCLUSION: HCCs should be considered in the differential diagnosis of carcinomas metastatic to the face, even in the absence of liver symptoms. 相似文献