Retino-pulvinar pathway of the cat brain

Peculiarities on axonal distribution and termination of the retinal ganglionar cells within the limits of the thalamic pulvinar nuclei have been studied in 10 cats by means of the radioautography method combined with silver nitrate impregnation (Fink--Heimer technique). The ganglionar cells have projections on two pulvinar nuclei -- the lateral and the inferior. The medial pulvinar nucleus has no similar connections. The retinal projections in the pulvinar nuclear complex are bilateral and nearly symmetrical, the contralateral projections of the pathway somewhat predominate.     

Genetic analysis of the Hsm3 protein domain structure in yeast <Emphasis Type="Italic">Saccharomyces cerevisiae</Emphasis>

Gene HSM3 encodes the Hsm3 protein involved in the minor branch in the system responsible for the correction of mismatched bases in DNA structure and controls replicative and reparative spontaneous mutagenesis in yeast Saccharomyces cerevisiae. Spontaneous and UV-induced mutagenesis was studied in three mutant alleles of gene HSM3, and repair effectivity of artificial heteroduplexes was assessed in DNA molecule. The resuts of these studies allowed establishment of the protein domain structure of protein Hsm3 and functions of each domain: the N-terminal domain is responsible for binding to mispaired bases, and the C-terminal domain ensures the interaction with other proteins involved in the system of mismatched base correction.