Purification and characterization of angiotensin-converting enzyme (ACE) from sheep lung

Molecular Biology Reports - Angiotensin-converting enzyme (ACE, EC 3.4.15.1) in the renin-angiotensin system regulates blood pressure by catalyzing angiotensin I to the vasoconstrictor angiotensin...     

Transgenic mouse models for studying adult neurogenesis

The mammalian hippocampus shows a remarkable capacity for continued neurogenesis throughout life. Newborn neurons, generated by the radial neural stem cells (NSCs), are important for learning and memory as well as mood control. During aging, the number and responses of NSCs to neurogenic stimuli diminish, leading to decreased neurogenesis and age-associated cognitive decline and psychiatric disorders. Thus, adult hippocampal neurogenesis has garnered significant interest because targeting it could be a novel potential therapeutic strategy for these disorders. However, if we are to use neurogenesis to halt or reverse hippocampal-related pathology, we need to understand better the core molecular machinery that governs NSC and their progeny. In this review, we summarize a wide variety of mouse models used in adult neurogenesis field, present their advantages and disadvantages based on specificity and efficiency of labeling of different cell types, and review their contribution to our understanding of the biology and the heterogeneity of different cell types found in adult neurogenic niches.     

The Role of Oxidative Stress,Renal Inflammation,and Apoptosis in Post Ischemic Reperfusion Injury of Kidney Tissue: the Protective Effect of Dose-Dependent Boric Acid Administration

Biological Trace Element Research - Ischemia/reperfusion (I/R) injury is associated with a strong inflammatory and oxidative stress response to hypoxia and reperfusion that impair organ function....     

Latitudinal shifts in mangrove species worldwide: evidence from historical occurrence records

Consequences of global climate change on mangrove habitats are ambiguous owing to multifaceted factors. In this study, we examined historical occurrences of ten common mangrove species and quantified the rate of latitudinal shift as a possible response to climate change. The Global Biodiversity Information Facility (GBIF) was used to gather occurrence of mangrove species. We found that nine of ten species have been shifting poleward since the 1950s. Overall mean latitudinal shift rates of mangrove species were significantly higher in Australia than in North America (1.7 and 1.3 latitude degrees per decade, respectively). In Australia, mean temperature and precipitation of localities decreased as mangrove species shifted towards drier regions at higher latitudes. However, in North America and West Africa, mean temperature of localities seems relatively stable, whereas precipitation slightly decreased. We provide new quantitative information on shifts in occurrence of common mangrove species worldwide under a changing climate. We confirm the poleward movement of mangrove species over the past 70 years and suggest that local mean temperature and precipitation can act as key drivers of mangrove range shifts. We also advise that poleward latitudinal shifts in mangrove species should be taken into account when establishing new nature reserves.