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Ethnobotanical study of plants revealed that the local community of Ghalegy, District Swat, invariably uses 126
species of 59 families for various purposes. Based on their traditional local uses, fifty- seven species ( 4512%) were classified
as medicinal, forty-seven as fire wood ( 3713%) , forty- five as forage ( 3517%) , twenty- eight as honey bee species
( 2212%) , twenty- seven as vegetable species ( 2114%) , 25 as edible fruits ( 14 wild and 11cultivated) , thirteen as timber
wood ( 1013%) , twelve as ornamental ( 91 5%) , eleven as furniture wood, ten as shelter and thatch makers
( 719%) , ten as fencing ( 719%) , five as poisonous ( 4%) , four as religiousPsuperstitious species, three species used
in making hand sticks and wooden tools ( 21 4%) , three as utensil cleaner species ( 214%) , three as evil repellent and
one as fish poisoning species. The area is in plant resources and traditional knowledge but it needs ecological management
for its sustainability. 相似文献
83.
Summary
Sorghum vulgare Pers. a tropical fodder crop significantly reduced the vertical growth and drymass of Sorghum vulgare, Pennisetum americanum, Zea mays and Setaria italica. Aqueous extracts of various plant parts, field soils and decaying mulch significantly reduced germination, radicle growth and water contents of all test species. The toxicity levels were depending upon the plant parts used in the biossay experiments and the sensitivity of the test species. It is suggested that the Sorghum fields be rotated with other crops to maximize the crop productivity. 相似文献
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Teresa Cuéllar Farrukh Azeem Mamy Andrianteranagna François Pascaud Jean‐Luc Verdeil Hervé Sentenac Sabine Zimmermann Isabelle Gaillard 《The Plant journal : for cell and molecular biology》2013,73(6):1006-1018
The grape berry provides a model for investigating the physiology of non‐climacteric fruits. Increased K+ accumulation in the berry has a strong negative impact on fruit acidity (and quality). In maturing berries, we identified a K+ channel from the Shaker family, VvK1.2, and two CBL‐interacting protein kinase (CIPK)/calcineurin B‐like calcium sensor (CBL) pairs, VvCIPK04–VvCBL01 and VvCIPK03–VvCBL02, that may control the activity of this channel. VvCBL01 and VvCIPK04 are homologues of Arabidopsis AtCBL1 and AtCIPK23, respectively, which form a complex that controls the activity of the Shaker K+ channel AKT1 in Arabidopsis roots. VvK1.2 remained electrically silent when expressed alone in Xenopus oocytes, but gave rise to K+ currents when co‐expressed with the pairs VvCIPK03–VvCBL02 or VvCIPK04–VvCBL01, the second pair inducing much larger currents than the first one. Other tested CIPK–CBL pairs expressed in maturing berries were found to be unable to activate VvK1.2. When activated by its CIPK–CBL partners, VvK1.2 acts as a voltage‐gated inwardly rectifying K+ channel that is activated at voltages more negative than –100 mV and is stimulated upon external acidification. This channel is specifically expressed in the berry, where it displays a very strong induction at veraison (the inception of ripening) in flesh cells, phloem tissues and perivascular cells surrounding vascular bundles. Its expression in these tissues is further greatly increased upon mild drought stress. VvK1.2 is thus likely to mediate rapid K+ transport in the berry and to contribute to the extensive re‐organization of the translocation pathways and transport mechanisms that occurs at veraison. 相似文献
86.
Ashiya Buckels Yue Zhang Jing Jiang Mohammad Athar Farrukh Afaq Lalita Shevde-Samant Stuart J. Frank 《Biochemistry and Biophysics Reports》2020
Melanoma is the most aggressive skin cancer. Its aggressiveness is most commonly attributed to ERK pathway mutations leading to constitutive signaling. Though initial tumor regression results from targeting this pathway, resistance often emerges. Interestingly, interrogation of the NCI-60 database indicates high growth hormone receptor (GHR) expression in melanoma cell lines. To further characterize melanoma, we tested responsiveness to human growth hormone (GH). GH treatment resulted in GHR signaling and increased invasion and migration, which was inhibited by a GHR monoclonal antibody (mAb) antagonist in WM35, SK-MEL 5, SK-MEL 28 and SK-MEL 119 cell lines. We also detected GH in the conditioned medium (CM) of human melanoma cell lines. GHR, JAK2 and STAT5 were basally phosphorylated in these cell lines, consistent with autocrine/paracrine GH production. Together, our results suggest that melanomas are enriched in GHR and produce GH that acts in an autocrine/paracrine manner. We suggest that GHR may constitute a therapeutic target in melanoma. 相似文献