Metabolomic Profiling and Neuroprotective Effects of Purslane Seeds Extract Against Acrylamide Toxicity in Rat’s Brain

Neurochemical Research - Acrylamide (ACR) is an environmental pollutant with well-demonstrated neurotoxic and neurodegenerative effects in both humans and experimental animals. The present study...     

Growth and Physiology of Maize (Zea mays L.) in a Nickel-Contaminated Soil and Phytoremediation Efficiency Using EDTA

Journal of Plant Growth Regulation - Nickel (Ni) element is strongly phytotoxic at high concentrations for several plants, but due to its dual behavior and complicated chemistry, it has received...     

Coarser taxonomic resolutions are informative in revealing fish community abundance trends for the world’s warmest coral reefs

Coral Reefs - The Arabian Gulf is a natural laboratory to examine how subtropical coral reef ecosystems might change in responding to recurring heating events because of uniquely high water...     

Structure-based prediction of protein–protein interactions between GhWlim5 Domain1 and GhACTIN-1 proteins: a practical evidence with improved fibre strength

Cotton fibre quality is a multigenic trait. Genetic modification of different genes to achieve high quality fibre is difficult without knowing the mechanism lying behind genes interaction. Based on background knowledge an attempt to explore the potential structural interactions between Gossypium hirsutum Wlim5 domain1 and Gossypium hirsutum ACTIN-1 proteins was done in current study. Sequence features of the LIM domain1 of GhWlim5 protein were identified through multiple sequence alignment analysis, and a phylogenetic tree was built to identify evolutionary relationships between sequences. Conservation indicated the evolutionary importance of side chain residues and the presence of several aliphatic and/or bulky residues, which stabilize the protein core and facilitate packing of zinc fingers. The structures of GhWlim5 domain1 and GhACTIN-1 proteins were modelled and validated through computational methods. Validation of GhACTIN-1 and GhWlim5 domain1 structures indicated good structural quality with 99.7% and 100% of the favoured number of residues in allowed regions and Z-score, within the ranges of − 9.87 and − 4.17, respectively. Docking analysis indicated various possible modes of interaction between these two proteins with favourable binding affinities. Based on our strong binding interaction results between GhWlim5 domain1 and GhACTIN-1 proteins, we further investigated the role of over-expression of GhWlim5 by transformation in cotton plants under fibre specific promoter and transgenic plants displayed significant increases in fibre strength.

     

Silver-coated magnetic nanoparticles as an efficient delivery system for the antibiotics trimethoprim and sulfamethoxazole against E. Coli and S. aureus: release kinetics and antimicrobial activity

BioMetals - Trimethoprim and sulfamethoxazole are prescribed for a broad spectrum of bacteria. However, the use of these medicines is restricted due to the risk of microbial resistance in the body....     

Mitoxantrone Inhibits FMLP-Induced Degenerative Changes in Human Neutrophils

Molecular Biology - Neutrophils fight with invading pathogens through various mechanisms including degranulation, phagocytosis, and the release of neutrophil extracellular traps (NETs). This study...     

Marginal lands for bioenergy in China; an outlook in status,potential and management

Energy consumption and CO₂ emissions have been increasing continuously over the past few decades in China and there is a pressing need to replace the fossil fuel‐based economy with an efficient low‐carbon system, tailor‐made to future requirements. China is starting an energy transition with the aim of building an energy system for the future. China has made tremendous progress in increasing the amount of renewable energy and reducing the cost of renewable energy over the last 20 years. According to the 14th 5 year plan, China aims to incorporate 20% of renewable energy to the primary energy mix and attain 27% reduction in CO₂ emissions. Bioenergy crops constitute a significant proportion of biomass‐based bioenergy and have recently been promoted by the Chinese Government to help overcome food and fuel conflict. Steps are being taken to promote bioenergy crops on marginal lands in China, and various regions across the country with soil marginality have been evaluated for bioenergy crop cultivation. The present paper reviews the status of bioenergy in China and the potential status of marginal lands from different regions of China. It also elaborates on some of the policies, subsidies and incentives allocated by the Chinese Government for the promotion of biomass‐based energy. Land management and plant improvement strategies were discussed, which are effective in making marginal lands suitable for bioenergy crop cultivation. Managing planting strategies, intercropping and crop rotation are effective management practices used in China for the utilization of marginal lands. A national investigation is desirable for creating an inventory of technical and economic potential of biomass feedstocks that could be planted on marginal lands. This would assist with highlighting the pros and cons of using marginal lands for bioenergy production and effective policy making.