全文获取类型
收费全文 | 570篇 |
免费 | 22篇 |
出版年
2023年 | 6篇 |
2022年 | 14篇 |
2021年 | 19篇 |
2020年 | 18篇 |
2019年 | 37篇 |
2018年 | 12篇 |
2017年 | 22篇 |
2016年 | 28篇 |
2015年 | 25篇 |
2014年 | 29篇 |
2013年 | 42篇 |
2012年 | 50篇 |
2011年 | 43篇 |
2010年 | 29篇 |
2009年 | 17篇 |
2008年 | 26篇 |
2007年 | 22篇 |
2006年 | 28篇 |
2005年 | 16篇 |
2004年 | 18篇 |
2003年 | 21篇 |
2002年 | 8篇 |
2001年 | 12篇 |
2000年 | 7篇 |
1999年 | 4篇 |
1998年 | 3篇 |
1997年 | 3篇 |
1996年 | 4篇 |
1995年 | 1篇 |
1994年 | 1篇 |
1992年 | 2篇 |
1991年 | 4篇 |
1990年 | 3篇 |
1989年 | 3篇 |
1988年 | 1篇 |
1985年 | 2篇 |
1984年 | 2篇 |
1982年 | 2篇 |
1977年 | 1篇 |
1974年 | 1篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1971年 | 2篇 |
1968年 | 1篇 |
1961年 | 1篇 |
排序方式: 共有592条查询结果,搜索用时 585 毫秒
491.
492.
493.
Cryptostegia madagascariensis is a plant native from Madagascar, belonging to the Apocynaceae that is invading the native vegetation in Northeast Brazil and threatening the unique riverine formations dominated by the carnauba palm. Individuals of C. madagascariensis cultivated in the campus of the Universidade Federal de Viçosa, state of Minas Gerais, Brazil, showing leaf spot symptoms of unknown etiology were observed. Two fungal species were found associated to such leaf spots: Colletotrichum gloeosporioides and a new species of Pseudocercospora. The latter was named Pseudocercospora cryptostegiae-madagascariensis and described herein. The discovery of those two fungal pathogens on C. madagascariensis coincide with the recognition that the weedy vine that is involved in the infestations in the Northeast of Brazil is not Cryptostegia grandiflora as formerly reported. These mycological findings are of greater importance now since C. madagascariensis is likely to become a target for biological control together with its former status in Brazil of an ornamental plant of limited relevance. 相似文献
494.
Time-place learning based on food association was investigated in the cichlids angelfish (Pterophyllum scalare) and pearl cichlid (Geophagus brasiliensis) reared in isolation, therefore eliminating social influence on foraging. During a 30-day period, food was placed in one side of the aquarium (containing three compartments) in the morning and in the opposite side in the afternoon. Learning was inferred by the number of correct side choices of all fish in each day of test (15th and 30th). During the test day fish were not fed. The angelfish learned to switch sides at the correct day period in order to get food, suggesting this species has time-place learning ability when individually reared. On the other hand, the same was not observed for pearl cichlid. 相似文献
495.
496.
Paim SL Pires ML Bittencourt LR Silva RS Santos RF Esteves AM Barreto AT Tufik S de Mello MT 《Chronobiology international》2008,25(2):321-331
The literature widely recognizes that shift workers have more health complaints than the general population. The objective of this study was to describe the prevalence of sleep complaints and verify the polysomnographic (PSG) variables of shift workers in two Brazilian nuclear power plants. We carried out a subjective evaluation with a sleep questionnaire. Based on these results, the interviewees that reported sleep-related complaints were referred for polysomnographic evaluation. Of the 327 volunteers initially evaluated by the sleep questionnaire, 113 (35%) reported sleep complaints; they were significantly older, had higher body mass index (BMI), and worked more years on shifts than those without sleep complaints. Of these 113, 90 met criteria for various sleep disorders: 30 (9%) showed obstructive sleep apnea (OSA), 18 (5.5%) showed limb movement, and 42 (13%) evidenced both sleep problems and had a significantly higher proportion of sleep stage 1 and arousals compared with the 23 shift workers that had no indices of sleep problems. The present study found that 90 (27.5%) of the evaluated participants met the PSG criteria of some type of clinical sleep disorder. This high proportion should be investigated for associations with other aspects of work, such as working hours, working schedule, years performing shift work, and access to health services. Due to the strong association between sleep disorders and the incidence of fatigue and sleepiness, the evaluation of the sleep patterns and complaints of shift workers is essential and should be considered to be one of the basic strategies of industry to prevent accidents. 相似文献
497.
Ktia de Lima Nechet Robert Weingart Barreto Eduardo S. G. Mizubuti 《Biological Control》2004,30(3):556-565
Sphaceloma poinsettiae, a scab-causing fungus that attacks wild poinsettia (Euphorbia heterophylla) was evaluated as a mycoherbicide. Plants representing nine different E. heterophylla accessions were tested and variable resistance levels to 10 different isolates of S. poinsettiae were observed. One isolate was selected based on its high aggressiveness; it caused scab that led to stem-girdling in the majority of plants belonging to most wild poinsettia accessions. Plants inoculated with conidial suspension developed low disease severity; suspensions of mycelial fragments caused higher disease severity. Viability of mycelium declined rapidly either in storage under room temperature or at 4 °C. After 25 days, 60% of mycelial fragments kept in distilled water at 4 °C or in 35% sterile sucrose solution germinated. Cultures of S. poinsettiae were capable of growing at temperatures ranging from 10 to 30 °C (maximum growth at 25 °C) whereas the mycelial fragments germinated at 20–30 °C. The highest mycelial yield occurred in potato-dextrose broth after culturing for 12 days at 168 rpm at room temperature. A host-range test involving 37 plant species in addition to wild poinsettia indicated that S. poinsettiae is highly specific to E. heterophylla. The viability of S. poinsettiae as a mycoherbicide depends on the development of suitable mass production, formulation, and inoculum preservation methods. On several occasions, this fungus has been observed to cause devastating epidemics in the field on this host; therefore, it should be considered a potential biocontrol agent of wild poinsettia. 相似文献
498.
Barreto EO Riederer I Arantes AC Carvalho VF Farias-Filho FA Cordeiro RS Martins MA Savino W e Silva PM 《Memórias do Instituto Oswaldo Cruz》2005,100(Z1):127-130
We previously reported that alloxan-induced diabetes results in reduction in the number and reactivity of mast cells at different body sites. In this study, the influence of diabetes on thymic mast cells was investigated. Thymuses from diabetic rats showed marked alterations including shrinkage, thymocyte depletion, and increase in the extracellular matrix network, as compared to those profiles seen in normal animals. Nevertheless, we noted that the number and reactivity of mast cells remained unchanged. These findings indicate that although diabetes leads to critical alterations in the thymus, the local mast cell population is refractory to its effect. This suggests that thymic mast cells are under a different regulation as compared to those located in other tissues. 相似文献
499.
The germ cell nuclear factor (GCNF) is a nuclear orphan receptor and a putative regulator of the pluripotent state of cells. Although it was first described in mouse germ cells, GCNF is also expressed in mouse and Xenopus embryos. By means of 5'RACE we have identified a novel isoform of Xenopus laevis GCNF that is predominantly expressed in germ cells, whereas both the oocyte and embryonic forms are expressed during Xenopus embryogenesis. EST database search revealed that the homologues of both isoforms are also transcribed in Xenopus tropicalis. 相似文献
500.
Modulation of IR/PTP1B interaction and downstream signaling in insulin sensitive tissues of MSG-rats 总被引:10,自引:0,他引:10
Hirata AE Alvarez-Rojas F Carvalheira JB Carvalho CR Dolnikoff MS Abdalla Saad MJ 《Life sciences》2003,73(11):1369-1381
PTP1B has been shown to be a negative regulator of the insulin signal transduction in insulin resistant states. Herein we investigated IR/PTP1B interaction and downstream signaling in insulin sensitive tissues of 10 and 28-week-old MSG-insulin resistant rats which represent different stages of insulin resistance. Our results demonstrated that the increase in PTP1B expression and/or association with IR in MSG animals may contribute to the impaired insulin signaling mainly in liver and muscle. Although, adipose tissue of 10-week-old MSG rats showed higher PTP1B expression and IR/PTP1B interaction, they were not sufficient to impair all insulin signaling since IRS-2 phosphorylation and association with PI3-kinase and Akt serine phosphorylation were increased, which may contribute for the increased adiposity of these animals. In 28-week-old-MSG rats there was an increase in IR/PTP1B interaction and reduced insulin signaling in liver, muscle and adipocytes, and a more pronounced insulin resistance. 相似文献