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461.
Mário Luís Garbin Tatiana Tavares Carrijo Jerônimo Boelsums Barreto Sansevero Andrea Sánchez-Tapia Fabio Rubio Scarano 《Perspectives in Plant Ecology, Evolution and Systematics》2012,14(4):257-265
We aimed to determine which factors explain the relative abundances of climbing plants in a tropical sandy coastal plant community, locally called restinga, in SE-Brazil, where facilitation is an important mechanism controlling shrub and tree diversity. The factors examined were: associations with host trees and shrubs, environmental conditions, associations with herbs and space. We surveyed a total of 84 vegetation patches within two hectares of open restinga vegetation. Climbers, trees, shrubs and herbs were sampled using an adapted cover pin frame approach. Partial constrained ordination (pRDA) was used to partition the variation of climber species relative abundances into four sources: trees and shrubs relative abundances, herb species relative abundances, environmental variables (patch architecture and size), and the spatial coordinates. Linear models were used to model the relationship of climber diversity as a function of the environmental factors. A total of 12 climber species belonging to 5 families were recorded. Associations between climber species with subordinate trees and shrubs were the major determinants of climber presence in these vegetation patches. The support for growth created by these trees and shrubs had a secondary role in explaining these patterns. We found no relationship between tree dominance and climber species dominance in each patch. However, most climbers were associated with subordinate shrubs. Trellis availability at the first stratum was related to greater climber diversity suggesting that subordinate trees and shrubs may be crucial to promote climber diversity in this plant community. Space and associations with herbs had a minor contribution to overall variation. While 15 years of research in the site associated local floristic diversity to dominant trees, our results demonstrate that climber diversity in this community is governed by interactions with subordinate host woody species related to the environmental support for growth created by such trees and shrubs. 相似文献
462.
Kahm M Navarrete C Llopis-Torregrosa V Herrera R Barreto L Yenush L Ariño J Ramos J Kschischo M 《PLoS computational biology》2012,8(6):e1002548
The intrinsic ability of cells to adapt to a wide range of environmental conditions is a fundamental process required for survival. Potassium is the most abundant cation in living cells and is required for essential cellular processes, including the regulation of cell volume, pH and protein synthesis. Yeast cells can grow from low micromolar to molar potassium concentrations and utilize sophisticated control mechanisms to keep the internal potassium concentration in a viable range. We developed a mathematical model for Saccharomyces cerevisiae to explore the complex interplay between biophysical forces and molecular regulation facilitating potassium homeostasis. By using a novel inference method ("the reverse tracking algorithm") we predicted and then verified experimentally that the main regulators under conditions of potassium starvation are proton fluxes responding to changes of potassium concentrations. In contrast to the prevailing view, we show that regulation of the main potassium transport systems (Trk1,2 and Nha1) in the plasma membrane is not sufficient to achieve homeostasis. 相似文献
463.
Fraga CM Costa TL Bezerra JC de Souza Lino R Vinaud MC 《Experimental parasitology》2012,130(2):146-151
Human cysticercosis by Taenia crassiceps is rare although it is considered of zoonotic risk, especially to immunocompromised individuals. Albendazole and praziquantel are widely used and effective in its treatment. Their active forms inhibit the glucose uptake by the parasite and induce muscle contractions that alter its glycogen levels interfering in the energetic metabolism of the parasite and leading to its death. The aim of this study was to evaluate alterations in glycolysis, the tricarboxylic acid cycle and glucose concentrations caused by low dosage treatments of the hosts with albendazole and praziquantel. Therefore, T. crassiceps intraperitoneally infected mice were treated by gavage feeding with 5.75 or 11.5 mg/kg of albendazole and 3.83 or 7.67 mg/kg of praziquantel. The treated mice were euthanized after 24 h and the cysticerci collected were morphologically classified into initial, larval or final phases. Concentrations of the organic acid produced and glucose were evaluated to detect alterations into the glycolysis and the tricarboxylic acid cycle pathways through chromatography and spectrophotometry. The low dosage treatment caused a partial blockage of the glucose uptake by the cysticerci in spite of the non significant difference between its concentrations. An activation of the tricarboxylic acid cycle was noted in the cysticerci that received the treatment due to an increase in the production of citrate, malate and α-ketoglutarate and the consumption of oxaloacetate, succinate and fumarate. The detection of α-ketoglutarate indicates that the cysticerci which were exposed to the drugs after host treatment present different metabolic pathways than the ones previously described after in vitro treatment. 相似文献
464.
Ademir Sergio Ferreira de Araujo Walderly Melgaço Bezerra Vilma Maria dos Santos Sandra Mara Barbosa Rocha Nilza da Silva Carvalho Maria do Carmo Catanho Pereira de Lyra Marcia do Vale Barreto Figueiredo Ângela Celis de Almeida Lopes Vania Maria Maciel Melo 《Antonie van Leeuwenhoek》2017,110(4):457-469
The Cerrado biome in the Sete Cidades National Park, an Ecological Reserve in Northeastern Brazil, has conserved its native biodiversity and presents a variety of plants found in other savannas in Brazil. Despite this finding the soil microbial diversity and community structure are poorly understood. Therefore, we described soil bacterial diversity and distribution along a savanna vegetation gradient taking into account the prevailing environmental factors. The bacterial composition was retrieved by sequencing a fragment of the 16S ribosomal RNA gene. The bacterial operational taxonomic units (OTUs) were assigned to 37 different phyla, 96 classes, and 83 genera. At the phylum level, a core comprised by Proteobacteria, Acidobacteria, Actinobacteria, Firmicutes, Verrucomicrobia and Planctomycetes, was detected in all areas of Cerrado. ‘Cerrado stricto sensu’ and ‘Cerradao’ share more similarities between edaphic properties and vegetation and also present more similar bacterial communities, while ‘Floresta decidual’ and ‘Campo graminoide’ show the largest environmental differences and also more distinct bacterial communities. Proteobacteria (26%), Acidobacteria (21%) and Actinobacteria (21%) were the most abundant phyla within the four areas. All the samples present similar bacteria richness (alpha diversity) and the observed differences among them (beta diversity) were more related to the abundance of specific taxon OTUs compared to their presence or absence. Total organic C, N and P are the main abiotic factors structuring the bacterial communities. In summary, our findings show the bacterial community structure was clearly different across the Cerrado gradient, but that these environments share a bacterial phylum-core comprising Proteobacteria, Acidobacteria, Actinobacteria, Verrucomicrobia and Planctomycetes with other Brazilian savannas. 相似文献
465.
Many studies show environmental enrichment is correlated with benefits to captive animals; however, one should not always assume this positive relationship given that enrichment increases the amount of resources that a territorial animal must defend and possibly affects its aggressive dynamics. In this study, we tested if environmental enrichment affects aggressive interactions in the aggressive fish Nile tilapia (Oreochromis niloticus). We compared fights staged between pairs of male tilapia of similar size (= matched in resource holding potential) in a novel arena that was either barren or enriched, to examine whether enrichment enhances territory value in line with theoretical predictions, with the potential for compromised welfare. We evaluated time elapsed until the first attack (latency), frequency of aggressive interactions and fight duration. We detected fight dynamic differences at the pair level. Higher resource value generated increased aggression but had no effect on fight duration or latency. This conclusion is in line with game theory predictions concerning resource value and contradicts the theory that enrichment of the environment will serve welfare purposes. 相似文献
466.
Daiane Borges Machado Elizabeth Williamson Julia M. Pescarini Flavia J. O. Alves Luís F. S. Castro-de-Araujo Maria Yury Ichihara Laura C. Rodrigues Ricardo Araya Vikram Patel Maurício L. Barreto 《PLoS medicine》2022,19(5)
BackgroundSocioeconomic factors have been consistently associated with suicide, and economic recessions are linked to rising suicide rates. However, evidence on the impact of socioeconomic interventions to reduce suicide rates is limited. This study investigates the association of the world’s largest conditional cash transfer programme with suicide rates in a cohort of half of the Brazilian population.Methods and findingsWe used data from the 100 Million Brazilian Cohort, covering a 12-year period (2004 to 2015). It comprises socioeconomic and demographic information on 114,008,317 individuals, linked to the “Bolsa Família” programme (BFP) payroll database, and nationwide death registration data. BFP was implemented by the Brazilian government in 2004. We estimated the association of BFP using inverse probability of treatment weighting, estimating the weights for BFP beneficiaries (weight = 1) and nonbeneficiaries by the inverse probability of receiving treatment (weight = E(ps)/(1-E(ps))). We used an average treatment effect on the treated (ATT) estimator and fitted Poisson models to estimate the incidence rate ratios (IRRs) for suicide associated with BFP experience. At the cohort baseline, BFP beneficiaries were younger (median age 27.4 versus 35.4), had higher unemployment rates (56% versus 32%), a lower level of education, resided in rural areas, and experienced worse household conditions. There were 36,742 suicide cases among the 76,532,158 individuals aged 10 years, or older, followed for 489,500,000 person-years at risk. Suicide rates among beneficiaries and nonbeneficiaries were 5.4 (95% CI = 5.32, 5.47, p < 0.001) and 10.7 (95% CI = 10.51, 10.87, p < 0.001) per 100,000 individuals, respectively. BFP beneficiaries had a lower suicide rate than nonbeneficiaries (IRR = 0.44, 95% CI = 0.42, 0.45, p < 0.001). This association was stronger among women (IRR = 0.36, 95% CI = 0.33, 0.38, p < 0.001), and individuals aged between 25 and 59 (IRR = 0.41, 95% CI = 0.40, 0.43, p < 0.001). Study limitations include a lack of control for previous mental disorders and access to means of suicide, and the possible under-registration of suicide cases due to stigma.ConclusionsWe observed that BFP was associated with lower suicide rates, with similar results in all sensitivity analyses. These findings should help to inform policymakers and health authorities to better design suicide prevention strategies. Targeting social determinants using cash transfer programmes could be important in limiting suicide, which is predicted to rise with the economic recession, consequent to the Coronavirus Disease 2019 (COVID-19) pandemic.In a quasi-experimental study, Daiane Borges Machado and colleagues investigate the association between rates of suicide and the Bolsa Familia cash transfer program in the 100 Million Brazilian Cohort. 相似文献
467.
Thessika Hialla Almeida Araujo Fernanda Khouri Barreto Alcantara Luiz Carlos Júnior Aline Cristina Andrade Mota Miranda 《Memórias do Instituto Oswaldo Cruz》2014,109(4):448-451
Human T-cell lymphotropic virus type 1 (HTLV-1) is mainly associated with two
diseases: tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP/HAM) and
adult T-cell leukaemia/lymphoma. This retrovirus infects five-10 million individuals
throughout the world. Previously, we developed a database that annotates sequence
data from GenBank and the present study aimed to describe the clinical, molecular and
epidemiological scenarios of HTLV-1 infection through the stored sequences in this
database. A total of 2,545 registered complete and partial sequences of HTLV-1 were
collected and 1,967 (77.3%) of those sequences represented unique isolates. Among
these isolates, 93% contained geographic origin information and only 39% were related
to any clinical status. A total of 1,091 sequences contained information about the
geographic origin and viral subtype and 93% of these sequences were identified as
subtype “a”. Ethnicity data are very scarce. Regarding clinical status data, 29% of
the sequences were generated from TSP/HAM and 67.8% from healthy carrier individuals.
Although the data mining enabled some inferences about specific aspects of HTLV-1
infection to be made, due to the relative scarcity of data of available sequences, it
was not possible to delineate a global scenario of HTLV-1 infection. 相似文献
468.
Nuno Rainha Violante P. Medeiros Mariana Câmara Hélder Faustino João P. Leite Maria do Carmo Barreto Cristina Cruz Carlos A. Pacheco Duarte Ponte Anabela Bernardes da Silva 《Physiologia plantarum》2016,156(1):29-39
Plants with the crassulacean acid metabolism (CAM) express high‐metabolic plasticity, to adjust to environmental stresses. This article hypothesizes that irradiance and nocturnal temperatures are the major limitations for CAM at higher latitudes such as the Azores (37°45'N). Circadian CAM expression in Ananas comosus L. Merr. (pineapple) was assessed by the diurnal pattern of leaf carbon fixation into l ‐malate at the solstices and equinoxes, and confirmed by determining maximal phosphoenolpyruvate carboxylase (PEPC) activity in plant material. Metabolic adjustments to environmental conditions were confirmed by gas exchange measurements, and integrated with environmental data to determine CAM's limiting factors: light and temperature. CAM plasticity was observed at the equinoxes, under similar photoperiods, but different environmental conditions. In spring, CAM expression was similar between vegetative and flowering plants, while in autumn, flowering (before anthesis) and fructifying (with fully developed fruit before ripening) plants accumulated more l ‐malate. Below 100 µmol m?2 s?1, CAM phase I was extended, reducing CAM phase III during the day. Carbon fixation inhibition may occur by two major pathways: nocturnal temperature (<15°C) inhibiting PEPC activity and l ‐malate accumulation; and low irradiance influencing the interplay between CAM phase I and III, affecting carboxylation and decarboxylation. Both have important consequences for plant development in autumn and winter. Observations were confirmed by flowering time prediction using environmental data, emphasizing that CAM expression had a strong seasonal regulation due to a complex network response to light and temperature, allowing pineapple to survive in environments not suitable for high productivity. 相似文献
469.
MicroRNA Expression Signature Is Altered in the Cardiac Remodeling Induced by High Fat Diets 下载免费PDF全文
470.