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531.
Ezequiel M Fuentes-Pananá Violeta Larios-Serrato Alfonso Méndez-Tenorio Abigail Morales-Sánchez Carlos F Arias Javier Torres 《Memórias do Instituto Oswaldo Cruz》2016,111(3):200-208
Gastric (GC) and breast (BrC) cancer are two of the most common and deadly tumours.
Different lines of evidence suggest a possible causative role of viral infections for
both GC and BrC. Wide genome sequencing (WGS) technologies allow searching for viral
agents in tissues of patients with cancer. These technologies have already
contributed to establish virus-cancer associations as well as to discovery new tumour
viruses. The objective of this study was to document possible associations of viral
infection with GC and BrC in Mexican patients. In order to gain idea about cost
effective conditions of experimental sequencing, we first carried out an in
silico simulation of WGS. The next-generation-platform IlluminaGallx was
then used to sequence GC and BrC tumour samples. While we did not find viral
sequences in tissues from BrC patients, multiple reads matching Epstein-Barr virus
(EBV) sequences were found in GC tissues. An end-point polymerase chain reaction
confirmed an enrichment of EBV sequences in one of the GC samples sequenced,
validating the next-generation sequencing-bioinformatics pipeline. 相似文献
532.
Andrea Comba Luciana L. Almada Ezequiel J. Tolosa Eriko Iguchi David L. Marks Marianela Vara Messler Renata Silva Maite G. Fernandez-Barrena Elisa Enriquez-Hesles Anne L. Vrabel Bruno Botta Lucia Di Marcotulio Volker Ellenrieder Aldo R. Eynard Maria E. Pasqualini Martin E. Fernandez-Zapico 《The Journal of biological chemistry》2016,291(4):1933-1947
533.
Camila Pérez Roig Ezequiel González Martin Videla 《Agricultural and Forest Entomology》2023,25(3):404-415
- In peri-urban areas, many farmers are transitioning from conventional agriculture to agroecological practices to reduce pesticide input and preserving ecosystem services such as natural pest control. Field margins represent a stable habitat for arthropods, but community structure depends on many factors, including management type and vegetation features.
- We studied the effects of agroecological transitions and vegetation features on arthropods of horticultural field margins, focusing on three feeding guilds (herbivores, predators and parasitoids). We sampled arthropods using the beat-sheet method in five conventional fields and five under agroecological transition. We also measured vegetation height, richness, flower abundance and plant cover.
- Our results showed that arthropod diversity was higher in agroecological fields whereas herbivore abundance was lower, with a consistent pattern across most taxonomic orders. Vegetation features displayed multiple effects among functional and taxonomic groups. Herbivores did not respond to most vegetation variables whereas predators correlated with several, with similar trends among orders.
- We conclude that agroecological transitions and field margins with high vegetation richness and floral resources influence arthropod communities with potential benefits regarding pest regulation. These practices might be more effective if considered alongside other methods that enhance biodiversity and if they are consistent at a landscape scale.
534.
J. Isaïa A. Rivero O. Glaizot P. Christe R. Pigeault 《Proceedings. Biological sciences / The Royal Society》2020,287(1939)
A pervasive characteristic of parasite infections is their tendency to be overdispersed. Understanding the mechanisms underlying this overdispersed distribution is of key importance as it may impact the transmission dynamics of the pathogen. Although multiple factors ranging from environmental stochasticity to inter-individual heterogeneity may explain parasite overdispersion, parasite infection is also overdispersed in an inbred host population maintained under laboratory conditions, suggesting that other mechanisms are at play. Here, we show that the aggregated distribution of malaria parasites within mosquito vectors is partially explained by a temporal heterogeneity in parasite infectivity triggered by the bites of mosquitoes. Parasite transmission tripled between the mosquito''s first and last blood feed in a period of only 3 h. Surprisingly, the increase in transmission is not associated with an increase in parasite investment in production of the transmissible stage. Overall, we highlight that Plasmodium is capable of responding to the bites of mosquitoes to increase its own transmission at a much faster pace than initially thought and that this is partly responsible for overdispersed distribution of infection. We discuss the underlying mechanisms as well as the broader implications of this plastic response for the epidemiology of malaria. 相似文献
535.
Hernandez-Becerra Ezequiel Mendoza-Avila Monserrat Jiménez-Mendoza Daniel Gutierrez-Cortez Elsa Rodríguez-García Mario E. Rojas-Molina Isela 《Biological trace element research》2020,194(1):168-176
Biological Trace Element Research - This work determines the effect nopal consumption at different maturity stages (60, 200, 400, and 600 g) as the only calcium source in bone metabolism.... 相似文献
536.
Franco Ezequiel Chiarini 《Brittonia》2004,56(3):284-287
Solanum homalospermum (Solanum subgen.Leptostemonum) is described and illustrated from central Argentina.Solanum homalospermum is characterized by having heteromorphic gynoecia, strongly flattened seeds, unequal anthers, and gemmiferous roots. 相似文献
537.
Braulio M. Fraga Melchor G. Hernández Javier G. Luis Rafael Estevez Juan L. Báez Manuel Rivero 《Phytochemistry》1977,16(2):265-267
A new sesquiterpene ester, linkiol with a daucane skeleton was isolated from Ferula linkii. 相似文献
538.
Background
The Golgi apparatus in mammals appears as a ribbon made up of interconnected stacks of flattened cisternae that is positioned close to the centrosome in a microtubule-dependent manner. How this organisation is achieved and retained is not well understood. GMAP210 is a long coiled-coil cis-Golgi associated protein that plays a role in maintaining Golgi ribbon integrity and position and contributes to the formation of the primary cilium. An amphipathic alpha-helix able to bind liposomes in vitro has been recently identified at the first 38 amino acids of the protein (amphipathic lipid-packing sensor motif), and an ARF1-binding domain (Grip-related Arf-binding domain) was found at the C-terminus. To which type of membranes these two GMAP210 regions bind in vivo and how this contributes to GMAP210 localisation and function remains to be investigated. 相似文献539.
540.