Antigenic differences between endozoites and cystozoites of Toxoplasma gondii

Antigenic differences between the cystozoite and endozoite of Toxoplasma gondii were found using fluorescent antibody staining. Antisera against the cystozoite reacted against only the cystozoite, whereas antisera against the endozoite reacted against both endozoite and cystozoite. Absorption of sera with endozoites removed only positive reactions with endozoites. These findings are the first to suggest antigenic differences between these two forms of Toxoplasma.     

Primary malignant fibrous histiocytoma of the breast

Clinical, light microscopic, electron microscopic and immunocytochemical features of 4 cases (3 women and 1 man) of primary malignant fibrous histiocytoma (MFH) of the breast are presented. The literature is reviewed and the diagnosis and treatment discussed. The good outcome is stressed and local excision or simple mastectomy recommended as appropriate treatment.     

Hydrology of Lake Atnsjøen and River Atna

The hydrological investigations in the Atna basin started in 1917 with discharge measurements at the outlet of Lake Atnsjøen. Ice data are available from the lake since 1950 and water temperature data from 1980. With the start of the FORSKREF program in 1986 the number of hydrological stations increased substantially and included also snow measurements. During the FORSKREF period 1986–98 the annual mean discharge was 8% lower than during the normal period 1931–60. The annual flood is highest during the snow melt in spring, an exception was 1987 when a rain flood in October was the annual high. The spring flood in early June 1995 was the largest ever recorded and had a 100–200 year return period. The water temperature is low above tree-line at 1000 m a. s. l., rarely exceeding 7–8?°C. The temperature increases gradually with decreasing altitude and is periodically above 15?°C at 400 m a. s. l. The Atna Lake is an important heat source for the river downstream. In this lake, wind mixing normally prevents the development of a strong summer thermocline. The lake usually freezes over in late November and has a stable ice cover of 50–90 cm thickness in early spring. The ice normally breaks up in late May; thus the mean ice-covered period is 6 months. The ice cover on the river is less stable and rather large ice-runs are common on the lower part of River Atna. The snow measurements are carried out in April in a small subbasin between 800 and 1200 m a. s. l. The snow cover is unevenly distributed due to strong wind transport, but the pattern is more or less the same from one season to another. The mean snow accumulation in this basin is equivalent to 205 mm of precipitation.     

Soluble interleukin-2 receptor and soluble CD8 antigen levels in serum from patients with non-resectable lung cancer

Summary In a preliminary longitudinal study two women with histologically verified adenocarcinoma of the lung, without simultaneous infectious or inflammatory conditions, were seen every 2 weeks until death. In one of the patients serum soluble interleukin-2 receptor (sIL-2R) levels rose progressively while the levels for the other patient increased during the second half of the observation period. Serum soluble CD8 antigen (sCD8 Ag) showed a pattern dissimilar to the one for sIL-2R. In a retrospective cross-sectional study circulating levels of sIL-2R and sCD8 Ag were measured before explorative thoracotomy in a total of 65 patients with histologically proven non-resectable carcinoma of the lung. The sIL-2R levels were significantly increased independently of histological subclassification while sCD8 Ag was increased only in patients with small-cell lung cancer. There was no correlation between pre-operative values and length of survival.