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71.
Marreiro DN do Perpetuo Socorro C Martins M de Sousa SS Ibiapina V Torres S Pires LV do Nascimento Nogueira N Lima JM do Monte SJ 《Biological trace element research》2007,120(1-3):42-50
The objective of this study was to assess urinary excretion of zinc and evaluation parameters of metabolic control in type
2 diabetic patients. Thirty-one type 2 diabetic patients, of both genders, with 5.8 ± 5.6 years average time of the disease,
age range 20–60 years, were selected. Evaluation of the nutritional status was performed using anthropometric measurements.
To evaluate food consumption, the 3-day alimentary log method was used, and its analysis was performed using a software. Determination
of urinary zinc was by atomic absorption spectrophotometry. From the obtained results, it was concluded that 51.6% of the
patients were overweight. The mean of found waist circumference was 100.4 and 92.2 cm for men and women, respectively. Blood
glucose and glycated hemoglobin values were higher than reference values, and plasma albumin concentration was adequate. The
median of found urinary zinc excretion was 474.9 μg/24 h, within normal standards (300–600 μg/day). Regarding diet composition,
calorie and protein concentration were above recommendation, while mean zinc concentration was adequate. This data allow the
conclusion that the evaluated patients presented adequate urinary zinc excretion in comparison with reference values. 相似文献
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A novel approach to DNase I-sensitivity analysis was applied to examining genes of the spermatogenic pathway, reflective of
the substantial morphological and genomic changes that occur during this program of differentiation. A new real-time PCR-based
strategy that considers the nuances of response to nuclease treatment was used to assess the nuclease susceptibility through
differentiation. Data analysis was automated with the K-Lab PCR algorithm, facilitating the rapid analysis of multiple samples
while eliminating the subjectivity usually associated with Ct analyses. The utility of this assay and analytical paradigm as applied to nuclease-sensitivity mapping is presented. 相似文献
74.
Zanin Fabiana Couto Freitas Natália Chagas Pinto Renan Terassi Máximo Wesley Pires Flausino Diniz Leandro Eugenio Cardamone Paiva Luciano Vilela 《Molecular biology reports》2022,49(3):1973-1984
Molecular Biology Reports - Small auxin-up RNA (SAUR) genes form a wide family supposedly involved in different physiological and developmental processes in plants such as leaf senescence, auxin... 相似文献
75.
Cavalcanti-de-Albuquerque Joao Paulo de-Souza-Ferreira Eduardo de Carvalho Denise Pires Galina Antonio 《Neurochemical research》2022,47(2):470-480
Neurochemical Research - Glucose and oxygen (O2) are vital to the brain. Glucose metabolism and mitochondria play a pivotal role in this process, culminating in the increase of reactive O2 species.... 相似文献
76.
Valsecchi Elena Coppola Emanuele Pires Rosa Parmegiani Andrea Casiraghi Maurizio Galli Paolo Bruno Antonia 《Biodiversity and Conservation》2022,31(4):1175-1196
Biodiversity and Conservation - The monk seal is the most endangered pinniped worldwide and the only one found in the Mediterranean, where its distribution and abundance have suffered a drastic... 相似文献
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The galactose‐binding lectin isolated from Bauhinia bauhinioides Mart seeds inhibits neutrophil rolling and adhesion via primary cytokines 下载免费PDF全文
Deysen Kerlla Fernandes Bezerra Girão Benildo Sousa Cavada Alana de Freitas Pires Timna Varela Martins Álvaro Xavier Franco Cecília Mendes Morais Kyria Santiago do Nascimento Plinio Delatorre Helton Colares da Silva Celso Shiniti Nagano Ana Maria Sampaio Assreuy Pedro Marcos Gomes Soares 《Journal of molecular recognition : JMR》2015,28(5):285-292
In this study, the amino acid sequence and anti‐inflammatory effect of Bauhinia bauhinioides (BBL) lectin were evaluated. Tandem mass spectrometry revealed that BBL possesses 86 amino acid residues. BBL (1 mg/kg) intravenously injected in rats 30 min prior to inflammatory stimuli inhibited the cellular edema induced by carrageenan in only the second phase (21% – 3 h, 19% – 4 h) and did not alter the osmotic edema induced by dextran. BBL also inhibited carrageenan peritoneal neutrophil migration (51%), leukocyte rolling (58%) and adhesion (68%) and the neutrophil migration induced by TNF‐α (64%). These effects were reversed by the association of BBL with galactose, demonstrating that the carbohydrate‐binding domain is essential for lectin activity. In addition, BBL reduced myeloperoxidase activity (84%) and TNF‐α (68%) and IL1‐β (47%) levels. In conclusion, the present investigation demonstrated that BBL contains highly homologous isolectins, resulting in a total of 86 amino acid residues, and exhibits anti‐inflammatory activity by inhibiting neutrophil migration by reducing TNF‐α and IL1‐β levels via the lectin domain. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
79.
Diana P. Pires Diana Vilas Boas Sanna Sillankorva Joana Azeredo 《Journal of virology》2015,89(15):7449-7456
Antimicrobial resistance constitutes one of the major worldwide public health concerns. Bacteria are becoming resistant to the vast majority of antibiotics, and nowadays, a common infection can be fatal. To address this situation, the use of phages for the treatment of bacterial infections has been extensively studied as an alternative therapeutic strategy. Since Pseudomonas aeruginosa is one of the most common causes of health care-associated infections, many studies have reported the in vitro and in vivo antibacterial efficacy of phage therapy against this bacterium. This review collects data of all the P. aeruginosa phages sequenced to date, providing a better understanding about their biodiversity. This review further addresses the in vitro and in vivo results obtained by using phages to treat or prevent P. aeruginosa infections as well as the major hurdles associated with this therapy. 相似文献
80.