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31.
Background
Some diseases, like tumors, can be related to chromosomal aberrations, leading to changes of DNA copy number. The copy number of an aberrant genome can be represented as a piecewise constant function, since it can exhibit regions of deletions or gains. Instead, in a healthy cell the copy number is two because we inherit one copy of each chromosome from each our parents. 相似文献32.
Optimization of mycophenolic acid production in solid state fermentation using response surface methodology 总被引:7,自引:0,他引:7
A K Sadhukhan MV Ramana Murthy R Ajaya Kumar E V S Mohan G Vandana C Bhar K Venkateswara Rao 《Journal of industrial microbiology & biotechnology》1999,22(1):33-38
Mycophenolic acid (MPA) can be produced in solid state fermentation. An isolate of Penicillium brevi-compactum ATCC 16024 grown on moist wheat bran produced a titre of 425 mg per kg of wheat bran. Central composite rotatable design
and response surface methodology were employed to derive a statistical model for media optimization towards production of
mycophenolic acid. Five levels with a five factorial design were adopted. The correlation coefficient was 0.82, ensuring a
satisfactory adjustment of the model to the experimental values. This statistical design was very effective in improving the
titre of mycophenolic acid up to 3286 mg per kg of wheat bran.
Received 24 July 1998/ Accepted in revised form 4 December 1998 相似文献
33.
C Nageswara Raju S Sailaja S Pavan Kumari SJ Dhoble V Ramesh Kumar MV Ramanaiah B Sudhakar Reddy 《Luminescence》2013,28(2):162-168
This article reports on the optical properties of 0.5% mol of Sm3+, Dy3+ ion‐doped B2O3‐TeO2‐Li2O‐AlF3 (LiAlFBT) glasses. The glass samples were characterized by optical absorption and emission spectra. Judd‐Ofelt theory was applied to analyze the optical absorption spectra and calculate the intensity parameters and radiative properties of the emission transitions. The emission spectra of Sm3+ and Dy3+:LiAlFBT glasses showed a bright reddish‐orange emission at 598 nm (4G5/2 → 6H7/2) and an intense yellow emission at 574 nm (4F9/2 → 6H13/2), respectively. Full width at half maximum (FWHM), stimulated emission cross section, gain bandwidth and optical gain values were also calculated to extend the applications of the Sm3+ and Dy3+:LiAlFBT glasses. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献