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171.
172.
P G Nazarov A P Volgarev S A Ermakov 《Biulleten' eksperimental'no? biologii i meditsiny》1978,85(6):721-723
The following correlations were revealed in the parallel study of leukocyte migration in vitro in the presence of a specific antigen and of spontaneous RNA and DNA synthesis in the cultured lymphocytes: 1) a direct correlation between the RNA and DNA synthesis in lymphocytes; 2) a close correlation between the antigen-induced migration and the levels of RNA and DNA synthesis. The effect of the antigen was evidenced by the inhibition or stimulation of leukocyte migration. A high ratio of RNA synthesis to DNA synthesis corresponded to the migration inhibition and a low one--to the migration stimulation. The ratio value varied mainly on account of the changes in the level of DNA synthesis. Participation of T and B cells in the regulation of the antigen-induced leukocyte mobility is discussed. 相似文献
173.
L I Frantsevich B V Sabinevski? A D Komissar A A Ermakov V I Kryzhanovski? Iu A Mikitiuk V A Arkhipchuk G M Panov A D Kolesnik I S Filimonov 《Radiobiologiia》1992,32(3):357-363
Evaluation of the zoogenic transfer of radionuclides from the 30-km zone around the Chernobyl NPP was necessary because of the enormous heavily polluted territory and mighty flow of migratory birds who tended to large rivers, the Dnieper and Pripyat. The integral estimate of the transferred amount was obtained as a product of three variables: the transfer factor (0.0077 m2/kg for 137Cs; 0.0107 m2/kg for 90Sr), the density of birds (0.002 kg/m2, at the mass of migrants about 5000 t per year), and the total fund of radionuclides throughout the territory. The upper estimated limit of the annual transfer rate was 5.5 Ci (2E + 11 Bq) for 137 Cs and 1.8 Ci (6.7E + 10 Bq) for 90 Sr. Restrictions of hunting are recommended within the northern part of the Kiev reservoir. 相似文献
174.
V A Spivak T P Molchanova N V Ermakov Iu N Tokarev R F Gar'kavtseva 《Biokhimii?a (Moscow, Russia)》1979,44(5):816-821
An E-like abnormal hemoglobin was detected in a hematological patient and one of the members of her family. The composition of blood hemolyzates was characterized using acetate cellulose electrophoresis. The abnormal beta-chain was isolated by ion-exchange chromatography of total globin on CM-cellulose. Using peptide mapping of the abnormal beta-chain trypsin hydrolysates, it was shown that the amino acid substitution occurs in peptide beta T3. The amino acid analysis and determination of the abnormal fragment C-terminal amino acid allowed to establish the locus and type of this substitution. The first case of hemoglobin E(alpha 2 beta 2 26Glu leads to Lys) identification on the territory of the USSR is reported. 相似文献
175.
176.
Relaxation of tensions of the surface of Xenopus laevisembryos at the late blastula stage leads to deep and diverse developmental defects and increased variability in mutual position and volume ratios of the axial rudiments. Here, we demonstrate that the development of such embryos was markedly normalized if the relaxed tensions were restored in one of two ways: (1) isotropic stretching of the blastocoel roof induced by the incubation of relaxed embryos in a hypotonic medium or (2) anisotropic stretching of embryos on two needles. In the latter case, we succeeded in restoring the morphological axis not only after longitudinal stretching but also after transverse stretching, and the new axis had signs of anteroposterior polarity. The role of isotropic and anisotropic tensions in organization of the early amphibian development is discussed. 相似文献
177.
The kinetics of hemoglobin (Hb) reactions with carbon monoxide were calculated for a number of classical schemes: with one, two, four binding sites and an allosteric scheme with T- and R-conformers. The developed theory predicts the existence of only one relaxation time for every scheme the values of which depends on the velocity constants, saturation degree and the Hb concentration. 相似文献
178.
The ESR method was used to study free-radical disturbances in tissues of mouse liver and spleen exposed in vitro to gamma-radiation and fission neutrons. It was shown that both types of radiation induced damages to basic chemical components of the cell, namely, DNA, lipids, proteins, and water. The radiochemical yields of each radical registered were obtained and RBE of neutrons were evaluated with a reference to the formation in tissues of radicals of each type. Membrane lipids were shown to be markedly injured by neutrons. 相似文献