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991.
992.
Erin M. Myers Tiffany I. Harwell Elizabeth L. Yale Abigail M. Lamb W. Anthony Frankino 《PloS one》2013,8(11)
Maladaptive hybridization, as determined by the pattern and intensity of selection against hybrid individuals, is an important factor contributing to the evolution of prezygotic reproductive isolation. To identify the consequences of hybridization between Drosophila pseudoobscura and D. persimilis, we estimated multiple fitness components for F1 hybrids and backcross progeny and used these to compare the relative fitness of parental species and their hybrids across two generations. We document many sources of intrinsic (developmental) and extrinsic (ecological) selection that dramatically increase the fitness costs of hybridization beyond the well-documented F1 male sterility in this model system. Our results indicate that the cost of hybridization accrues over multiple generations and reinforcement in this system is driven by selection against hybridization above and beyond the cost of hybrid male sterility; we estimate a fitness loss of >95% relative to the parental species across two generations of hybridization. Our findings demonstrate the importance of estimating hybridization costs using multiple fitness measures from multiple generations in an ecologically relevant context; so doing can reveal intense postzygotic selection against hybridization and thus, an enhanced role for reinforcement in the evolution of populations and diversification of species. 相似文献
993.
We compared haematocrits and blood haemoglobin concentrations of nestling House Wrens Troglodytes aedon in nests with relatively large numbers of haematophagous larvae of the blow fly Protocalliphora parorum (>6.4 large larvae/nestling) and nests in which exposure to larvae was severely reduced or eliminated (0–2.0 larvae/nestling). Heavily parasitized nestlings showed no reduction in haematocrit levels but a significant 28% reduction in haemoglobin levels. Previous research on avian response to chronic blood loss suggests that parasitized nestlings may show normal volumes of red blood cells as a result of a rapid production of new cells in response to blood loss and, additionally, as a result of swelling of individual cells left in the bloodstream after parasite feeding. Rapid erythropoiesis places high numbers of haemoglobin-poor, immature cells into the bloodstream which would explain the reduced haemoglobin levels of parasitized nestlings. Our results refute the conclusion that larval feeding has "little direct effect" on nestling wrens in this parasite–host system, drawn earlier by Johnson and Albrecht (1993) based on examination of haematocrits alone. Our results also strongly suggest that researchers wanting to measure effects of blood-feeding parasites on birds measure haemoglobin levels, not haematocrits. 相似文献
994.
The novel antineoplastic drug mitoxantrone was studied for its genotoxic effects in Drosophila melanogaster. In male germ cells, the clinical preparation Novantrone, the dihydrochloride salt of mitoxantrone, did not induce sex-linked recessive lethal mutations in feeding and injection experiments with adult flies, although statistically the results were inconclusive rather than truly negative. However, the free base mitoxantrone was weakly, but significantly genotoxic in this test (0.14% lethals/mM exposure concentration); this is most probably the result of prolonged exposure. On the other hand, both forms of mitoxantrone assayed were clearly genotoxic in the somatic mutation and recombination test of the wing. This test assays the cells of the proliferating imaginal wing discs of larvae. Depending on the feeding method used, the overall clone induction frequency was in the range of about 2-6 x 10(-5) per cell and cell generation and per mM exposure dose. Correction of these frequencies according to mean clone size led to slightly higher estimates (by about 5-25% higher). Although the majority of the clone induction events are due to mitotic recombination, a significant proportion can be attributed to mutational events (gene and chromosome mutations). The genotoxicity of mitoxantrone seems to depend mainly on impaired DNA synthesis in cycling cells owing to the compound's ability to inhibit topoisomerase II by intercalation into DNA. 相似文献
995.
D.E. Hoss D.S. Peters W.F. Hettler L.C. Clements 《Journal of experimental marine biology and ecology》1978,31(3):241-252
Several experiments were conducted with pinfish, Lagodon rhomboides (L.). and black sea bass, Centropristis striata (L.), to determine the practicality of using the rate of loss of 65Zn to estimate the metabolic rate of fish under natural conditions. No significant correlations were found between this and oxygen consumption, feeding rate, fish size, or temperature. Restricting fish movement had no consistent effect on zinc loss nor did elevated levels of inorganic zinc in the diet. Because of the lack of positive results, we concluded that the rate of loss of 65Zn is not a practical method for estimating field metabolism of fish. 相似文献
996.
997.
J W Delahunt R V Clements I D Ramsay J Newton W P Collins J Landon 《BMJ (Clinical research ed.)》1975,4(5997):621
Three patients with oligomenorrhoea and hirsutism thought to have the polycystic ovary syndrome were found to have only one ovarian cyst. Endocrine findings were similar to those found in the polycystic syndrome, but apart from the single cyst the ovaries were histologically normal; a biopsy specimen of a cyst showed normal follicular appearances and no evidence of luteinisation. These cysts may be the cause of this condition, producing abnormal amounts of ovarian steroids which modify the pituitary response. Further studies are needed, however, to determine this possibility. 相似文献
998.
A S Loginov K D Dzhalalov A N Erin L L Prilipko 《Biulleten' eksperimental'no? biologii i meditsiny》1986,101(1):26-28
The content of lipid peroxidation products in the plasma of patients with various forms of alcohol-induced liver disorders was investigated. Plasma levels of lipid hydroperoxides in this group of patients were found to be the same as in healthy controls. Plasma content of fluorescent products of lipid oxidation was significantly elevated in patients suffering from acute alcoholic hepatitis and active alcoholic liver cirrhosis, and especially in patients with edematoascitic syndrome. The dynamics of fluorescent product plasma level reduction significantly correlated with the improvement of clinical status in the treatment of abstinent patients. 相似文献
999.
Erin Wood Todd Nordeen Will M. Inselman Peter J. Mahoney John F. Benson 《The Journal of wildlife management》2022,86(3):e22201
Understanding the spatial ecology of small populations at the periphery of their range is important for identifying factors limiting population growth and developing sound management strategies. Bighorn sheep were reintroduced to Nebraska in 1981 and persist in a small population at the easternmost extent of the distribution of the species, where 1 of the 2 subpopulations is declining. Bighorn sheep space use and movement has been studied extensively in mountain and desert populations, but information is sparse from prairie populations in the Northern Great Plains. We investigated the spatial ecology of female bighorn sheep in Nebraska, USA, with global positioning system (GPS) telemetry. We tested the hypothesis that space use and movements would vary across seasons, years, and individuals but predicted that migration would involve relatively short distances in this translocated population (relative to native populations) occupying a fragmented landscape. Overall, females used smaller seasonal home ranges (3.3–7.8 km2) than most of those reported previously for the species and exhibited a high degree of variability in space use and movements across seasons, subpopulations, and individuals. Most females (92–100%) exhibited fidelity to their home ranges across seasons and years. Six females migrated between spatially distinct core lambing and winter ranges, although the distances (range = 7.9–8.7 km) and mean elevations (range = 31–41 m) between these core seasonal ranges were less than those reported for most native, migratory bighorn sheep populations. After accounting for variation in season, subpopulation, and years, home range size was positively associated with road density in both subpopulations (P < 0.001), suggesting that females incur greater energetic costs associated with greater space use in areas of higher fragmentation. Our results establish the basic spatial ecology of female bighorn sheep in Nebraska where their behavior appears to reflect the isolated nature of suitable habitat in this fragmented prairie landscape. 相似文献
1000.
Seybold Erin C. Fork Megan L. Braswell Anna E. Blaszczak Joanna R. Fuller Matthew R. Kaiser Kendra E. Mallard John M. Zimmer Margaret A. 《Ecosystems》2022,25(5):989-1005
Ecosystems - Ecosystems in the Anthropocene face pressures from multiple, interacting forms of environmental change. These pressures, resulting from land use change, altered hydrologic regimes, and... 相似文献