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651.
Graziella Migliorati Teresa Jezzi Cartesio Favalli Enrico Garaci Giovanni B. Rossi Enzo Bonmassar 《Cancer immunology, immunotherapy : CII》1995,12(2):177-179
Summary The natural killer (NK) cell activity of DBA/2J mice infected with the polycythemic variant of Friend leukemia virus (FLV-P) declines early after virus challenge, being non-detectable 2 weeks after FLV-P inoculation. Cells capable of suppressing the in vitro cytolytic activity of NK effector lymphocytes were detected in the spleen of infected mice. The mechanism of suppression could be based on cell-mediated impairment of NK effector function, or on antigenic competition from splenocytes expressing NK antigens elicited by FLV-P. 相似文献
652.
Enzo Santaniello Pierangela Ciuffreda Silvana Casati Laura Alessandrini Alessandro Repetto 《Journal of Molecular Catalysis .B, Enzymatic》2006,40(3-4):81-85
Lipases from Mucor miehei (MML) and Candida antarctica (CAL) are able to catalyze the monobenzoylation of the primary hydroxy group of 1,2- 1,4- or 1,5-diols with vinyl benzoate in an organic solvent, the reaction proceeding with high regioselectivity and moderate enantioselectivity. The lipase-catalyzed debenzoylation of 1,2-propanediol dibenzoate by alcoholysis with 1-octanol most satisfactorily occurred with Pseudomonas cepacia lipase absorbed onto celite that allowed also to prepare (R)-1-benzoyloxy-2-methylpropan-3-ol from 2-methyl-1,3-propanediol dibenzoate, a result complementary to MML-catalyzed benzoylation of 2-methyl-1,3-propanediol that affords the (S)-monobenzoate. 相似文献
653.
Summary A composite design technique was used to optimize the fermentation of whey by Kluyveromyces fragilis IMAT 1872. The experimental variables (temperature T, salts NP, yeast-extract YE and lactose level L), but not pH, were found to be significant at a level of 5%. The optimal operating conditions were determined (T=36.4°C, pH=5.1, NP=0.47% w/v, YE=0.114% w/v, and L=24.75 g/l). Temperature and lactose level exhibited a great influence on the biomass yield about the stationary point. Canonical analysis showed that these variables are not mutually independent. The optimal conditions will be used as starting point for a factorial design on a jar fermenter. 相似文献
654.
The acid-catalyzed reaction of D-mannitol 4 with bromoacetaldehyde diethyl acetal followed by periodate cleavage of the corresponding diacetal 5 afforded (4S, 2R, S)-2-bromomethyl-4-hydroxymethyl-1,3-dioxolane 3c in good yields, from which the title compound 1 is obtained by displacement of the bromine with lithium iodide. © 1995 Wiley-Liss, Inc. 相似文献
655.
Ultrastructural studies were performed on the blood cells of Planorbarius corneus. Spreading and round cell forms were observed. The spreading form can be distinguished from the round form by its abundant cytoplasm, pseudopods and irregularly shaped nucleus. Electron dense granules in the mitochondrial matrix are found in the round form and are lacking in the spreading form. Moreover, cellular apoptosis is observed in the round form. The ultrastructural findings and the previously described characteristics support the idea that the two cell forms belong to two basic cell types. 相似文献
656.
657.
Davide Malagoli Federica Boraldi Giulia Annovi Daniela Quaglino Enzo Ottaviani 《Cell and tissue research》2009,336(1):107-118
Autophagy is an evolutionary ancient process based on the activity of genes conserved from yeast to metazoan taxa. Whereas
its role as a mechanism to provide energy during cell starvation is commonly accepted, debate continues about the occurrence
of autophagy as a means specifically activated to achieve cell death. The IPLB-LdFB insect cell line, derived from the larval
fat body of the lepidoptera Lymantria dispar, represents a suitable model to address this question, as both autophagic and apoptotic cell death can be induced by various
stimuli. Using morphological and functional approaches, we have observed that the culture medium conditioned by IPLB-LdFB
cells committed to death by the ATPase inhibitor oligomycin A stimulates autophagic cell death in untreated IPLB-LdFB cells.
Moreover, proteomic analysis of the conditioned media suggests that, in IPLB-LdFB cells, oligomycin A promotes a shift towards
lipid metabolism, increases oxidative stress and specifically directs the cells towards autophagic activity.
Electronic Supplementary Material The online version of this article (doi:) contains supplementary material, which is available to authorized users.
This work was supported by an F.A.R. grant from the University of Modena and Reggio Emilia (D.M. and E.O.) and by an “Experimental
approaches to the study of evolution” grant from the Department of Animal Biology of the University of Modena and Reggio Emilia
(D.M.). 相似文献
658.
Dr. Enzo Insalaco 《Facies》1999,40(1):81-99
Summary This study documents the facies and fauna of Late Jurassic (Middle Oxfordian) coral reefs in England. Sedimentological and
palaeoecological analysis of these reefs distinguishes three generic reef types: (1) small reef patches and thickets associated
with siliciclastic deposits; (2) small reef patches and thickets associated with siliciclastic-free bioclastic grainstones
and packstones; and (3) biostromal units associated with deep water facies. The depositional environments of these reef types
are discussed. Two coral assemblages are identified: (1) the microsolenid assemblage; and (2) theThamnasteria, Isastraea, Fungiastraea andThecosmilia assemblage (Thamnasteria assemblage). TheThamnasteria assemblage developed in all shallow water environments in the study area, regardless of local environmental conditions. The
fauna is very eurytopic,r-selected and can tolerate significant environmental fluctuations on short temporal scales (sub-seasonal). The main control
on the development of the microsolenid assemblage was low light intensity, low background sedimentation rates and low hydrodynamic
energy levels. 相似文献