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Carolina Santos-Heredia Ellen Andresen Diego A. Zárate Federico Escobar 《Biodiversity and Conservation》2018,27(9):2379-2394
There is growing interest in evaluating the impact that management intensity of agroecosystems has on animal communities and their ecological functions. Dung beetles are a highly used focal taxon for assessing the effects of anthropogenic disturbances and management practices on biodiversity. In the Lacandona rainforest region in southern Mexico, we quantified several metrics of the dung beetle community (number of species, number of individuals, total biomass, mean beetle size) and four of their ecological functions (dung removal, soil excavation, seed dispersal, seed exhumation) in conserved rainforest and three agroforestry systems with different management intensities: rustic cocoa, polyculture cocoa, and rubber monoculture. We also assessed the correlation between dung removal and the other functions, as well as the relationships between functions and community metrics. Land-use type affected the dung beetle communities as well as their functions, with negative effects on response variables in the most intensely managed agroecosystems (polyculture cocoa and rubber). Rustic cocoa had values similar to those of the conserved forest for all functions and community metrics, except the mean number of species per trap. Dung removal was correlated with the other ecological functions. The mean number of species per trap was significantly associated with all four functions. In our study region rustic cocoa plantations favor the maintenance of a high proportion of dung beetle species and maintain their ecological functions. Our findings corroborate that agroecosystems with less intense management may contribute to buffering the effects of landscape homogenization caused by more intensely managed agroecosystems, such as rubber plantations. 相似文献
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Tricia L. May-Dracka Robert Arduini Andrea Bertolotti-Ciarlet Govinda Bhisetti Margot Brickelmaier Ellen Cahir-McFarland Istvan Enyedy Jason D. Fontenot Thomas Hesson Kevin Little Joe Lyssikatos Douglas Marcotte Timothy McKee Paramasivam Murugan Thomas Patterson Hairuo Peng Mia Rushe Laura Silvian Linda C. Burkly 《Bioorganic & medicinal chemistry letters》2018,28(10):1964-1971
Germinal center kinase-like kinase (GLK, also known as MAP4K3) has been hypothesized to have an effect on key cellular activities, including inflammatory responses. GLK is required for activation of protein kinase C-θ (PKCθ) in T cells. Controlling the activity of T helper cell responses could be valuable for the treatment of autoimmune diseases. This approach circumvents previous unsuccessful approaches to target PKCθ directly. The use of structure based drug design, aided by the first crystal structure of GLK, led to the discovery of several inhibitors that demonstrate potent inhibition of GLK biochemically and in relevant cell lines. 相似文献
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Ellen Andresen Víctor Arroyo-Rodríguez Michelle Ramos-Robles 《International journal of primatology》2018,39(3):443-465
Primate seed dispersal plays crucial roles in many ecological processes at various levels of biological organization: from plant population genetics and demography to community assembly and ecosystem function. Although research on primate seed dispersal has advanced significantly in the last 20–30 years, many aspects are still poorly understood. Here, we discuss some new challenges that we need to address, as well as some old ones that still need our attention, highlighting examples from the Neotropics. Despite new analytical tools from network theory, research on primate seed dispersal rarely takes a community-wide approach, thus limiting our understanding of its evolutionary, ecological, and conservation implications. Of particular relevance for conservation are changes caused by landscape-scale processes (e.g., forest loss and fragmentation), but these effects need to be assessed using a landscape approach, which is currently absent in primate seed dispersal research. Agroecosystems can play a key role in maintaining primate seed dispersal in anthropogenic landscapes, but this topic remains poorly studied. Primate seed dispersal research will need to play a role in refaunation projects aimed at restoring plant–animal interactions. Old challenges that we still need to address include the long-term effects of primate declines on plant populations and communities, and the role of primate seed dispersal in the regeneration of degraded habitats. If we take advantage of all tools provided by modern science, from powerful methods of data analyses to molecular techniques, and combine them with strong multidisciplinary collaborations, the future of primate seed dispersal research will indeed be exciting. 相似文献
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Scott P. Egan Glen R. Hood Ellen O. Martinson James R. Ott 《Current biology : CB》2018,28(24):R1370-R1374
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Integrating classical biological control with other management techniques such as herbicide, fire, mechanical control, grazing, or plant competition, can be the most effective way to manage invasive weeds in natural areas and rangelands. Biological control agents can be protected from potential negative impacts of these weed control methods through untreated refugia or by applying the treatment at a time when the agent is not vulnerable. A literature review of experiments that integrated biological control with other management strategies from 1987 to 2017 yielded 39 terrestrial and 16 aquatic studies. The tactics most frequently integrated with biological control were herbicide applications and plant competition. Despite numerous examples of successful programs and calls for more widespread integration of biological control with other weed management strategies, there was no increase in the number of studies reported annually over time. Additional studies investigating the ecological and economic benefits of integrated weed management are needed. 相似文献
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Ecoevolutionary feedbacks in predator–prey systems have been shown to qualitatively alter predator–prey dynamics. As a striking example, defense–offense coevolution can reverse predator–prey cycles, so predator peaks precede prey peaks rather than vice versa. However, this has only rarely been shown in either model studies or empirical systems. Here, we investigate whether this rarity is a fundamental feature of reversed cycles by exploring under which conditions they should be found. For this, we first identify potential conditions and parameter ranges most likely to result in reversed cycles by developing a new measure, the effective prey biomass, which combines prey biomass with prey and predator traits, and represents the prey biomass as perceived by the predator. We show that predator dynamics always follow the dynamics of the effective prey biomass with a classic ¼‐phase lag. From this key insight, it follows that in reversed cycles (i.e., ¾‐lag), the dynamics of the actual and the effective prey biomass must be in antiphase with each other, that is, the effective prey biomass must be highest when actual prey biomass is lowest, and vice versa. Based on this, we predict that reversed cycles should be found mainly when oscillations in actual prey biomass are small and thus have limited impact on the dynamics of the effective prey biomass, which are mainly driven by trait changes. We then confirm this prediction using numerical simulations of a coevolutionary predator–prey system, varying the amplitude of the oscillations in prey biomass: Reversed cycles are consistently associated with regions of parameter space leading to small‐amplitude prey oscillations, offering a specific and highly testable prediction for conditions under which reversed cycles should occur in natural systems. 相似文献
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