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71.
Great-granny’s Garden: a living archive and a sensory garden 总被引:1,自引:0,他引:1
Since 2003, the Botanical Garden in Oslo has been involved in a project coordinated by the Norwegian Genetic Resource Centre.
The wide range of work supervised by this centre includes conservation of ornamental plants. Our garden has been responsible
for the registration and collecting of ornamentals in Southeast-Norway and has a special responsibility for the conservation
of Paeonia species and cultivars. As a result of the project, Great-granny’s Garden was opened to the public in 2008. It has two objectives.
Firstly, it shall be a living archive of Norway’s horticultural heritage. Although proven hardy, easy to grow, and long-lived,
old varieties of traditional ornamentals are rapidly disappearing. We aim to keep these old-fashioned varieties for sustainable
use in future horticulture and encourage people to use them in present day gardening, both in new gardens and in the restoration
of old ones. Secondly, the garden is designed as a sensory garden for people with dementia, in cooperation with Oslo’s Resource
Centre for Dementia and Psychiatric Care of the Elderly. It is enclosed by a picked fence and by shrubs, offers rest on several
benches, and has a paved and easy to follow round-walk among traditional garden elements and plants with a lush variety of
colours, forms, and scents. A sensory garden stimulates many senses, evokes pleasant emotions, brings out long-forgotten memories,
and stimulates communication. Sensory gardens are therefore considered an important tool in the therapy of dementia. 相似文献
72.
A. R. Hagen T. Sæther L. Borgen R. Elven O. E. Stabbetorp C. Brochmann 《Plant Systematics and Evolution》2002,230(3-4):203-219
The high polyploids Cerastium alpinum (8x) and C. nigrescens (12x) were investigated in a mixed population in central Norway to evaluate whether hybridisation has resulted in continuous variation
in morphology and genetic markers, a hypothesis previously proposed to account for the extensive taxonomic confusion in this
species group. Isozyme, fertility, and morphological (37 characters) variation were examined among 347, 265, and 237 plants,
respectively. A PCO analysis based on 23 quantitative morphological characters identified two main groups, corresponding to
C. alpinum and C. nigrescens. The groups were also clearly separated in isozyme markers, several qualitative morphological characters, and chromosome numbers.
Only 20 plants (8.4%) were more or less intermediate in the PCO analysis. These plants had a parental or hybrid isozyme multilocus
phenotype and typically few well-developed anthers, low pollen stainability, and no seed set. Several plants within the C. nigrescens group also had reduced pollen stainability. These results indicate that later-generation hybrids and/or backcrosses towards
C. nigrescens are formed. Thus, interspecific, interploidal gene flow probably occurs, but at rates that are insufficient to break down species integrity.
Received July 5, 2000 Accepted August 2, 2001 相似文献
73.
Melissa Carrillo Suraj Pandey Juan Sanchez Moraima Noda Ishwor Poudyal Luis Aldama Tek Narsingh Malla Elin Claesson Weixiao Yuan Wahlgren Denisse Feliz Vukica Šrajer Michał Maj Leticia Castillon So Iwata Eriko Nango Rie Tanaka Tomoyuki Tanaka Luo Fangjia Marius Schmidt 《Structure (London, England : 1993)》2021,29(7):743-754.e4
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74.
Viola hirta is widespread in most of Europe but rare in Norway, occurring in four isolated enclaves around the Oslo Fjord. Allozymic and morphological patterns of variation were studied in 320 individuals of Viola hirta (2n = 20) and its relatives V. collina (2n = 20), V. odorata (2n = 20), and V. suavis (2n = 40) from 22 Norwegian populations. Ongoing introgression from both V. collina and V. odorata , as hypothesised by several authors, was not supported by our data. All hybrids proved to be primary ones and, apparently, introgression is rare. However, allozyme markers suggested that V. hirta may have been affected by ancient introgression from V. collina and possibly also from the East European V. ambigua (2n = 40) during its evolutionary history. Geographical differentiation, presumably relatively recent and post-glacial, was evident in V. hirta. Variation occurred also between and within V. odorata populations, most likely a consequence of independent introductions by man. No variation was observed in V. collina or in V suavis. A key to the Norwegian species of subsection Viola and their primary hybrids based on morphological characters is provided in Flora Nordica note No. 26. 相似文献
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Arginine-rich cell-penetrating peptides (CPPs) can enter cells non-endocytotically, despite that transport of charge across a membrane should be formally associated with an extremely high Born energy barrier. We studied partitioning of several derivatives of the CPP penetratin in a water-octanol two-phase system in presence of natural phospholipids to explore if solvation by ion-pairing to hydrophobic counter-ions may serve as a mechanism for cell internalisation. We demonstrate that anionic lipids can aid peptide partitioning into octanol. Particularly efficient partitioning into octanol is observed with an arginine-rich penetratin compared to a lysine-rich derivative. Substituting tryptophans for phenylalanines results in poor partitioning into octanol, due to decreased overall peptide hydrophobicity. Partitioning into octanol is dependent of phospholipid type and the peptides induced structural changes in the lipid assemblies found in octanol. Attachment of carboxyfluorescein as a model cargo was found to enhance peptide partitioning into octanol. We discuss our results with respect to theoretical electrostatic energies, empirical hydrophobicity scales and in terms of implications for CPP uptake mechanisms. An important improvement of the theoretical transfer energies is obtained when, instead of singular ions, the insertion of ion-paired dipolar species is considered. 相似文献
79.
Elin Lehrmann Zoan R Afanador Amy Deep-Soboslay Gloria Gallegos William D Darwin Ross H Lowe Allan J Barnes Marilyn A Huestis Jean L Cadet Mary M Herman Thomas M Hyde Joel E Kleinman William J Freed 《Addiction biology》2008,13(1):105-117
The present study examines the diagnostic challenges of identifying ante-mortem illicit substance use in human postmortem cases. Substance use, assessed by clinical case history reviews, structured next-of-kin interviews, by general toxicology of blood, urine and/or brain, and by scalp hair testing, identified 33 cocaine, 29 cannabis, 10 phencyclidine and nine opioid cases. Case history identified 42% cocaine, 76% cannabis, 10% phencyclidine and 33% opioid cases. Next-of-kin interviews identified almost twice as many cocaine and cannabis cases as Medical Examiner (ME) case histories, and were crucial in establishing a detailed lifetime substance use history. Toxicology identified 91% cocaine, 68% cannabis, 80% phencyclidine and 100% opioid cases, with hair testing increasing detection for all drug classes. A cocaine or cannabis use history was corroborated by general toxicology with 50% and 32% sensitivity, respectively, and with 82% and 64% sensitivity by hair testing. Hair testing corroborated a positive general toxicology for cocaine and cannabis with 91% and 100% sensitivity, respectively. Case history corroborated hair toxicology with 38% sensitivity for cocaine and 79% sensitivity for cannabis, suggesting that both case history and general toxicology underestimated cocaine use. Identifying ante-mortem substance use in human postmortem cases are key considerations in case diagnosis and for characterization of disorder-specific changes in neurobiology. The sensitivity and specificity of substance use assessments increased when ME case history was supplemented with structured next-of-kin interviews to establish a detailed lifetime substance use history, while comprehensive toxicology, and hair testing in particular, increased detection of recent illicit substance use. 相似文献
80.
We here describe that soluble HLA-DQ2 (sDQ2) molecules, when expressed in Drosophila melanogaster S2 insect cells without a covalently tethered peptide, associate tightly with the D. melanogaster calcium binding protein DCB-45. The interaction between the proteins is stable in S2 cell culture and during affinity purification,
which is done at high salt concentrations and pH 11.5. After affinity purification, the sDQ2/DCB-45 complex exists in substantial
quantities next to a small amount of free heterodimeric sDQ2 and large amounts of aggregated sDQ2 free of DCB-45. Motivated
by the stable complex formation and our interest in the development of reagents which inhibit HLA-DQ2 peptide binding, we
have further characterized the sDQ2/DCB-45 interaction. Several lines of evidence indicate that an N-terminal fragment of
DCB-45 is involved in the interaction with the peptide binding groove of sDQ2. Further mapping of this fragment of 54 residues
identified a pentadecapeptide with high affinity for sDQ2 which may serve as a lead compound for the design of HLA-DQ2 blockers. 相似文献