全文获取类型
收费全文 | 5226篇 |
免费 | 373篇 |
国内免费 | 1篇 |
出版年
2023年 | 41篇 |
2022年 | 104篇 |
2021年 | 159篇 |
2020年 | 122篇 |
2019年 | 166篇 |
2018年 | 193篇 |
2017年 | 155篇 |
2016年 | 202篇 |
2015年 | 260篇 |
2014年 | 284篇 |
2013年 | 404篇 |
2012年 | 395篇 |
2011年 | 412篇 |
2010年 | 272篇 |
2009年 | 236篇 |
2008年 | 244篇 |
2007年 | 249篇 |
2006年 | 178篇 |
2005年 | 172篇 |
2004年 | 135篇 |
2003年 | 128篇 |
2002年 | 109篇 |
2001年 | 90篇 |
2000年 | 111篇 |
1999年 | 78篇 |
1998年 | 58篇 |
1997年 | 30篇 |
1996年 | 35篇 |
1995年 | 27篇 |
1994年 | 15篇 |
1993年 | 17篇 |
1992年 | 24篇 |
1991年 | 20篇 |
1990年 | 16篇 |
1989年 | 26篇 |
1988年 | 18篇 |
1987年 | 16篇 |
1986年 | 23篇 |
1985年 | 19篇 |
1984年 | 29篇 |
1983年 | 24篇 |
1982年 | 24篇 |
1981年 | 15篇 |
1980年 | 35篇 |
1979年 | 30篇 |
1978年 | 27篇 |
1977年 | 25篇 |
1976年 | 14篇 |
1974年 | 13篇 |
1973年 | 13篇 |
排序方式: 共有5600条查询结果,搜索用时 250 毫秒
101.
Abarghooi Kahaki Fatemeh Monzavi Sakineh Bamehr Hadi Bandani Eshagh Payandeh Zahra Jahangiri Abolfazl Khalili Saeed 《International journal of peptide research and therapeutics》2020,26(4):2077-2087
International Journal of Peptide Research and Therapeutics - Membrane proteins play important functions, such as cellular communication and transferring materials in the cell. Many membrane... 相似文献
102.
Pithecellobium dulce has been used in traditional medicine to treat various ailments owing to its restorative properties. The biological activities and chemical profiles of the lipophilic fraction of P. dulce bark and leaves were assessed herein. Fatty acid methyl esters (FAME) and unsaponifiable matter (USM) were prepared and analyzed by GC/MS. A total of 40 compounds were identified in the bark saponifiable fraction, whereas 9 compounds were annotated in the leaves. Palmitic acid methyl ester was the major compound identified accounting for 41.48 % of the bark and 19.03 % of the leaves composition. Besides, linolenic acid methyl ester (22.40 %) and linoleic acid (12.69 %) were annotated in the leaves saponifiable fraction. A total of 63 compounds were detected in the bark USM and 4 compounds were identified in the leaves. Phytol represented the major component in the leaves (52.57 %) followed by lupeol (20.68 %) and lupenone (8.60 %). Meanwhile, n‐dodecane dominated in the bark USM accounting for 24.69 % of the total composition. The leaves and bark lipophilic fractions revealed moderate antioxidant and antibacterial activities. Both extracts showed no antifungal activity. No cytotoxicity was observed for both lipophilic fractions. P. dulce offers a good source of antioxidant compounds that can be introduced to food and pharmaceutical industry. 相似文献
103.
Developing highly efficient, cost effective, and environmentally friendly electrocatalysts for the oxygen evolution reaction (OER), oxygen reduction reaction (ORR), and hydrogen evolution reaction (HER) is of interest for sustainable and clean energy technologies, including metal–air batteries and fuel cells. In this work, the screening of electrocatalytic activities of a series of single metallic iron, cobalt, and nickel nanoparticles and their binary and ternary alloys encapsulated in a graphitic carbon shell toward the OER, ORR, and HER in alkaline media is reported. Synthesis of these compounds proceeds by a two‐step sol–gel and carbothermal reduction procedure. Various ex situ characterizations show that with harsh electrochemical activation, the graphitic shell undergoes an electrochemical exfoliation. The modified electronic properties of the remaining graphene layers prevent their exfoliation, protect the bulk of the metallic cores, and participate in the electrocatalysis. The amount of near‐surface, higher‐oxidation‐state metals in the as‐prepared samples increases with electrochemical cycling, indicating that some metallic nanoparticles are not adequately encased within the graphite shell. Such surface oxide species provide secondary active sites for the electrocatalytic activities. The Ni–Fe binary system gives the most promising results for the OER, and the Co–Fe binary system shows the most promise for the ORR and HER. 相似文献
104.
105.
106.
The current study characterizes and analyzes glow curves obtained from phosphate glass doped with different concentrations of lanthanum. Kinetic parameters of the glow curves obtained from beta‐irradiated phosphate glass samples doped with lanthanum were determined using a newly designed deconvoluted software. The obtained results from the analyses indicated that the glow curves of the phosphate glass samples were composed of five overlapping peaks. The activation energies of the five electron traps were located between 0.622 and 1.133 eV. The obtained kinetic parameters were evaluated using the designed software and another two methods and all revealed good agreement. The first three traps displayed non‐first‐order behaviour, while the two deep traps obeyed nearly first‐order kinetics. 相似文献
107.
108.
109.
Yara A. Samra Mohamed F. Hamed Ahmed R. El‐Sheakh 《Journal of biochemical and molecular toxicology》2020,34(5)
Acetaminophen (APAP) overdose leads to liver injury. NLRP3 inflammasome is a key player in APAP‐induced inflammation. Also, apoptosis and liver regeneration play an important role in liver injury. Therefore, we assessed allicin's protective effect on APAP‐induced hepatotoxicity and studied its effect on NLRP3 inflammasome and apoptosis. Mice in the APAP group were injected by APAP (250 mg/kg, intraperitoneal). The allicin‐treated group received allicin orally (10 mg/kg/d) during 7 days before APAP injection. Serum and hepatic tissues were separated 24 hours after APAP injection. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), albumin, alkaline phosphatase (ALP), and hepatic malondialdehyde (MDA) were assessed using the colorimetric method. Hepatic NLRP3 inflammasome, caspase‐1, and interleukin‐1β (IL‐1β) were estimated using enzyme‐linked immunosorbent assay. Hepatic Bcl‐2 and Ki‐67 were investigated by immunohistochemistry. APAP significantly increased AST, ALT, and ALP, whereas allicin significantly decreased their levels. Also, APAP significantly decreased albumin and allicin significantly improved it. APAP produced changes in liver morphology, including inflammation and massive coagulative necrosis. Allicin protected the liver from APAP‐induced necrosis, apoptosis, and hepatocellular degeneration via increasing Bcl‐2 and Ki‐67 levels. APAP significantly increased the hepatic MDA, whereas allicin significantly prevented this increase. APAP markedly activated the NLRP3 inflammasome pathway and consequently increased the production of caspase‐1 and IL‐1β. Interestingly, we found that allicin significantly inhibited NLRP3 inflammasome activation, which resulted in decreased caspase‐1 and IL‐1β levels. Allicin has a hepatoprotective effect against APAP‐induced liver injury via the decline of oxidative stress and inhibition of the inflammasome pathway and apoptosis. Therefore, allicin might be a novel tool to halt the progression of APAP‐stimulated hepatotoxicity. 相似文献
110.