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151.
TDP‐1, the Caenorhabditis elegans ortholog of TDP‐43, limits the accumulation of double‐stranded RNA
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Studies of the last decade have shown that most bacteria exist in natural ecosystems as specifically organized, attached to substrates biofilms rather than as freely floating plankton cells. The formation of these biofilms is a complex and highly regulated process. The development of biofilm communities is a primary strategy of bacterial survival not only in the external environment but also in the bodies of infected macroorganisms. In these organisms, bacteria are joined by complicated cell–cell associations, which makes them functionally similar to multicellular organisms. In the present review, we consider the structural organization of biofilms, factors affecting initiation of the biofilm formation, differential expression of bacterial genes at various stages of the biofilm development and their regulation. The significance of studies in this field for medicine, in particular, for prevention and protection against pathogenic bacteria, is discussed. 相似文献
154.
Oganesian GA Romanova IV Aristakesian EA Kuzik VV Makina DM Morina TIu Khramenkova AE Artamokhina IV Belova VA 《Zhurnal evoliutsionno? biokhimii i fiziologii》2008,44(3):250-257
Based on sleep deprivation-produced changes of electrographic parameters of the wakefulness--sleep cycle (WSC) in rats and common frogs, dynamics of activity of tyrosine hydroxylase, the key enzyme of dopamine synthesis, was studied immunohistochemically in substantia nigra and nigrostriatal pathway in rats and in striatum, paraventricular organ, and extrahypothalamic pathways in frogs. There are revealed changes in dynamics of tyrosine hydroxylase in rats and in common frogs after the 6-h sleep deprivation and after 2 h of postdeprivation sleep. This allows determining the degree of participation of corticostriatal neuroregulatory and hypothalamo-pituitary neurosecretory systems and their role in regulation of WSC. Possible evolutionary peculiarities of morphofunctional differences in homoiothermal and poikilothermal animals are discussed. 相似文献
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G. A. Finenko B. E. Anninsky Z. A. Romanova G. I. Abolmasova A. E. Kideys 《Hydrobiologia》2001,459(1-3):177-186
We assessed the effects of rotenone on aquatic invertebrate communities by comparing four prairie wetlands treated with rotenone to four control sites. Data collected one week before and three weeks after treatment in the fall of 1998 were paired to assess short-term effects, while data collected in spring 1998 and spring 1999 were paired to assess longer-term effects and recovery rates. Data were collected on 14 taxa of benthic invertebrates collected in Ekman grab samples, and 23 taxa of planktonic-nektonic invertebrates collected in water-column samples. Each data set was analyzed separately with redundancy analysis to assess effects in the two habitats sampled. Significant short-term effects were detected on invertebrates in the water column and abundance of several taxonomic groups declined sharply after treatment. The greatest declines were observed in zooplankton abundance; effects on macroinvertebrates were much less pronounced. Suppression of water-column taxa was short-lived, as significant effects were no longer evident during May 1999. In contrast, no significant short-term effect was evident in the benthic taxa. Our results indicate that fall applications of rotenone may briefly suppress plankton communities, but effects are short-lived. From a fisheries management perspective, fall applications may minimize effects on invertebrate communities and facilitate rapid recovery. 相似文献
157.
O M Grindel' V G Voronov N V Romanova I G Skoriatina S V Urakov 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》2001,51(5):572-582
Dynamic EEG study of patients with posttraumatic Korsakoff's syndrome (KS) with the application of complex analysis methods revealed a complicated pathological structure of the intercentral relations of cortical electrical activity. The interhemispheric EEG coherence between symmetrical frontal cortical areas are sharply reduced, while the intrahemispheric coherence are increased in comparison with the normal values. The proposed technique of segregation of statistically homogeneous spectro-coherent characteristics made it possible to reveal the earlier intercentral EEG relations formed by stable and variable coherence spectra. The structure formed by the stable and variable coherence spectra in KS differs from that reflected in the mean coherence levels. During the KS regression, the EEG coherence between the right and left frontal areas increased to the normal level, and the variable spectra are revealed. In the chronic KS syndrome, the pathological intercentral relations persist, while the variable relations in the frontal areas are absent. A reduction of pathologically decreased intrahemispheric coherence selectively revealed in the right hemisphere during the KS regression and formation of variable relations in this hemisphere point to a leading role of the right hemisphere in development of compensatory processes in KS. The reciprocal relations between the intra- and interhemispheric coherence and coherence dynamics in the theta rhythm suggest that pathological activity in the basal diencephalic structures plays an important role in formation of the pathological EEG pattern in KS. 相似文献
158.
Pattern and process in above-ground and below-ground components of grassland ecosystems 总被引:1,自引:0,他引:1
Abstract. This paper describes patterns of below-ground components in grassland ecosystems. It provides estimates of the contribution of below-ground organs to the total phytomass of the community and of different species to the below-ground phytomass; it describes the distribution of above- and below- ground organs of different species and the spatial and temporal correlation between above-ground and below-ground phyto-mass – both total standing crop and net primary production. 10 Siberian grasslands (meadows and steppes) were investigated during 15 yr. Ca. 70 % of the living phytomass is located in the soil and no less than 70 % of the net primary production is allocated in below-ground organs. Phytomass distribution in the soil layer is more homogeneous than above-ground. For some species the spatial distribution within 1-m2 plots of the green and below-ground phytomass is similar, for others it is quantitatively or qualitatively different. According to the dominance-diversity curve, the above-ground size hierarchy is much stronger than the below-ground one. The active growth of above- and below-ground organs of a species may occur at different times of the season and it varies from year to year. Allocation of organic substances to rhizomes and roots occurs simultaneously and with proportional intensity. 相似文献
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