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排序方式: 共有328条查询结果,搜索用时 15 毫秒
21.
PSF and p54(nrb)/NonO--multi-functional nuclear proteins 总被引:13,自引:0,他引:13
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Nihal Buzkan Serpil Karadaǧ Abdulmurat Kaya Saadettin Baloǧlu Angelantonio Minafra Yair Ben‐Dov 《Journal of Phytopathology》2010,158(6):448-449
Surveys were made in the main grape growing region (Southeast Anatolia) of Turkey for the occurrence of Grapevine leafroll‐associated virus‐5 (GLRaV‐5). Plant samples with typical leafroll symptoms and mealybugs, Planococcus ficus (Signoret) were used for assessing the occurrence of GLRaV‐5 by RT‐PCR. A 272 bp band representing GLRaV‐5 infection was successfully detected in plants and mealybugs in some vineyards of the Southeast Anatolia region and the virus is the first time reported in Turkish vineyards. 相似文献
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The evolution of bacterial pathogens from nonpathogenic ancestors is marked principally by the acquisition of virulence gene clusters on plasmids and pathogenicity islands via horizontal gene transfer. The flip side of this evolutionary force is the equally important adaptation of the newly minted pathogen to its new host niche. Pathoadaptive mutations take the form of modification of gene expression such that the pathogen is better fit to survive within the new niche. This mini-review describes the concept of pathoadaptation by loss of gene function. In this process, genes that are no longer compatible with the novel lifestyle of the pathogen are selectively inactivated either by point mutation, insertion, or deletion. These genes are called 'antivirulence genes'. Selective pressure sometimes leads to the deletion of large regions of the genome that contain antivirulence genes generating 'black holes' in the pathogen genome. Inactivation of antivirulence genes leads to a pathogen that is highly adapted to its host niche. Identification of antivirulence genes for a particular pathogen can lead to a better understanding of how it became a pathogen and the types of genetic traits that need to be silenced in order for the pathogen to colonize its new host niche successfully. 相似文献
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Rachel Ben-Shlomo Esther Neufeld Dov Berger Sarah Lenington Uzi Ritte 《Mammalian genome》2007,18(3):164-172
The t-haplotype, a variant of the proximal part of the mouse chromosome 17, is composed of at least four inversions and is inherited
as a single genetic unit. The haplotype causes embryonic mortality or male sterility when homozygous. Genes within the complex
are responsible for distortion of Mendelian transmission ratio in males. Thus, the t-haplotype in heterozygous males is transferred to over 95% of the progeny. We examined the dynamic and behavior of the t-haplotype in wild populations of the house mouse in Israel. The Israeli populations show high frequency (15%–20%) of both
partial and complete t-carrying mice, supporting the suggestion that the t-complex evolved in the M. domesticus line in the Israeli region. In one population that had the highest frequency of t-carrying individuals, we compared the level of gene diversity between t-carrying and normal mice in the marker’s loci: H-2 locus of the major histocompatibility complex (MHC) on the t-haplotype of chromosome 17, three microsatellites on other chromosomes, and the mitochondrial D-loop. Genetic variability
was high in all tested loci in both t and (+) mice. All t mice carried the same chromosome and showed the same H-2 haplotype. While t-carrying mice showed significant H-2 heterozygotes access, (+) mice expressed significant H-2 heterozygote deficiency. There
were no differences in the level of gene diversity between t and (+) mice in the other loci. Heterozygosity level at the MHC may be an additional factor in the selective forces balancing
the t-haplotype polymorphism. 相似文献
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Engineer pioneer plants respond to and affect geomorphic constraints similarly along water–terrestrial interfaces world‐wide 下载免费PDF全文
Dov Corenblit Andreas Baas Thorsten Balke Tjeerd Bouma François Fromard Virginia Garófano‐Gómez Eduardo González Angela M. Gurnell Borbála Hortobágyi Frédéric Julien Daehyun Kim Luc Lambs J. Anthony Stallins Johannes Steiger Eric Tabacchi Romain Walcker 《Global Ecology and Biogeography》2015,24(12):1363-1376
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Advances in sequencing technology have led to a sharp decrease in the cost of ''data generation''. But is this sufficient to ensure cost-effective and efficient ''knowledge generation''? 相似文献
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PURPOSE OF REVIEW: Despite clear treatment guidelines, a major part of the population is not achieving the recommended LDL cholesterol target levels. This fact is more prominent among high-risk populations in which the majority of patients are untreated or undertreated. RECENT FINDINGS: The review will elaborate on the key issues of treating large populations: patient compliance, drug efficacy, cost-benefit, and physician quality of care. SUMMARY: A programme aimed at improving control of hyperlipidemia should address all four issues. The primary care physician should be empowered and given tools for optimizing treatment. 相似文献
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