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111.
Denisa Blažková 《Folia Geobotanica》1973,8(3):225-230
Vesicular cavities in the lava fields of Northern Iceland communicate by small openings with the ground surface. Aeolian sediments, called the Icelandic Ioess, deposit over the bottom of these cavities, together with the reduced light intensity and equable microclimate, create specific biotopes occupied by sciophilous bryophytes andCystopteris fragilis. A new association within the allianceCtenidion Stefureac 1941—Cystopteri-Distichietum capillacei Bla?ková ass. nova— is described in the present paper. 相似文献
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Denisa Maceková Gustáv Ková? Jaroslav Hin?t Branislav Illek Jana Pere?ková ?elmíra Baro?ková Branislav Lí?ka 《Biologia》2009,64(2):409-413
Lipid peroxidation (LPX) can play an important role in the development of pathological changes of foetal and neonatal tissues.
We investigated LPX and biochemical parameters in plasma from mixed umbilical cord (m.u.c.) blood and acid-base balance (ABB)
parameters in m.u.c. blood of well-adapted full-term newborns. LPX products were estimated as thiobarbituric acid reacting
substances (TBARS) and were expressed by using of malondialdehyde (MDA) as a standard solution. Intensity of LPX was estimated
in vitro in m.u.c. blood plasma without and with added LPX activator (125 μM L-ascorbate plus 5 μM FeSO4) and in the incubated plasma (30 min, 37°C) under both conditions. Actual TBARS (3.51 ± 0.49 nmol/mL) were determined in
the non-incubated plasma without the added LPX activator. Approximately twice higher TBARS were found in the incubated plasma
without the LPX activator (7.29 ± 2.17 nmol/mL) or with it (8.57 ± 2.20 nmol/mL), as well as in the non-incubated plasma after
its addition (7.38 ± 1.98 nmol/mL). All analysed biochemical parameters (Fe, total iron-binding capacity, uric acid, proteins,
Mg, Ca, phosphate, glucose, K, Na, Cl, ALT, AST, GMT, CK, LD, HBD, AMS, ALP, ACP) and ABB parameters were within their reference
ranges. The actual TBARS levels were found being positively correlated with α-hydroxybutyrate dehydrogenase (HBD) activity and negatively with pO2. These results suggest that LPX in m.u.c. blood plasma might be activated. This activation could probably depend on extent
of hypoxia. TBARS and their formation in vitro could be suitable parameters of LPX in m.u.c. blood. 相似文献
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Petrak J Myslivcova D Man P Cmejla R Cmejlova J Vyoral D 《American journal of physiology. Gastrointestinal and liver physiology》2006,290(5):G1059-G1066
Iron-mediated organ damage is common in patients with iron overload diseases, namely, hereditary hemochromatosis. Massive iron deposition in parenchymal organs, particularly in the liver, causes organ dysfunction, fibrosis, cirrhosis, and also hepatocellular carcinoma. To obtain deeper insight into the poorly understood and complex cellular response to iron overload and consequent oxidative stress, we studied iron overload in liver-derived HepG2 cells. Human hepatoma HepG2 cells were exposed to a high concentration of iron for 3 days, and protein expression changes initiated by the iron overload were studied by two-dimensional electrophoresis and mass spectrometry. From a total of 1,060 spots observed, 21 spots were differentially expressed by iron overload. We identified 19 of them; 11 identified proteins were upregulated, whereas 8 identified proteins showed a decline in response to iron overload. The differentially expressed proteins are involved in iron storage, stress response and protection against oxidative stress, protein folding, energy metabolism, gene expression, cell cycle regulation, and other processes. Many of these molecules have not been previously suggested to be involved in the response to iron overload and the consequent oxidative stress. 相似文献
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Patrizia Aruta Denisa Muraru Andrada Camelia Guta Sorina Mihaila Niccolò Ruozi Chiara Palermo Basma Elnagar Sabino Iliceto Luigi P. Badano 《Cardiovascular ultrasound》2018,16(1):27