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41.
More productive environments typically have more species, although the specific form of this relationship is unclear and can vary with spatial scale. This relationship has received little direct attention in lotic systems, and thus the nature of the relationship is unclear, as is any effect of spatial scale. We examined the link between stream primary productivity and macroinvertebrate diversity in Spain and New Zealand and hypothesized that macroinvertebrate diversity would increase log-linearly with increasing productivity in both regions. We sampled 24 streams in Cantabria, Spain, and 24 in the central North Island, New Zealand. Algal primary productivity was approximately three times higher in Spanish streams, but taxonomic richness of invertebrates did not differ between the regions. Richness and Shannon diversity only responded to productivity in the New Zealand streams, exhibiting the predicted log-linear increase. In the Spanish streams, only the total number of individuals increased with productivity. However, when plotted on the same axes, richness in the Spanish streams simply occurred on the linear portion of the graph to the right of the New Zealand streams. We speculate that productivity in the Spanish streams never became low enough to constrain diversity, but did in the New Zealand streams. Combining results from the two regions, there is no evidence of a decline in diversity with higher productivity. 相似文献
42.
Habitat heterogeneity drives the geographical distribution of beta diversity: the case of New Zealand stream invertebrates 下载免费PDF全文
Anna Astorga Russell Death Fiona Death Riku Paavola Manas Chakraborty Timo Muotka 《Ecology and evolution》2014,4(13):2693-2702
To define whether the beta diversity of stream invertebrate communities in New Zealand exhibits geographical variation unexplained by variation in gamma diversity and, if so, what mechanisms (productivity, habitat heterogeneity, dispersal limitation, disturbance) best explain the observed broad‐scale beta diversity patterns. We sampled 120 streams across eight regions (stream catchments), spanning a north–south gradient of 12° of latitude, and calculated beta diversity (with both species richness and abundance data) for each region. We explored through a null model if beta diversity deviates from the expectation of stochastic assembly processes and whether the magnitude of the deviation varies geographically. We then performed multimodel inference analysis on the key environmental drivers of beta diversity, using Akaike's information criterion and model and predictor weights to select the best model(s) explaining beta diversity. Beta diversity was, unexpectedly, highest in the South Island. The null model analysis revealed that beta diversity was greater than expected by chance in all eight regions, but the magnitude of beta deviation was higher in the South Island, suggesting differences in environmental filtering and/or dispersal limitation between North and South Island. Habitat heterogeneity was the predominant driver of beta diversity of stream macroinvertebrates, with productivity having a secondary, and negative, contribution. This is one of the first studies accounting for stochastic effects while examining the ecological drivers of beta diversity. Our results suggest that local environmental heterogeneity may be the strongest determinant of beta diversity of stream invertebrates, more so than regional‐ or landscape‐scale variables. 相似文献
43.
Ann L. Montgomery Usha Ram Rajesh Kumar Prabhat Jha for The Million Death Study Collaborators 《PloS one》2014,9(1)
Background
Data on cause-specific mortality, skilled birth attendance, and emergency obstetric care access are essential to plan maternity services. We present the distribution of India''s 2001–2003 maternal mortality by cause and uptake of emergency obstetric care, in poorer and richer states.Methods and Findings
The Registrar General of India surveyed all deaths occurring in 2001–2003 in 1.1 million nationally representative homes. Field staff interviewed household members about events that preceded the death. Two physicians independently assigned a cause of death. Narratives for all maternal deaths were coded for variables on healthcare uptake. Distribution of number of maternal deaths, cause-specific mortality and uptake of healthcare indicators were compared for poorer and richer states. There were 10 041 all-cause deaths in women age 15–49 years, of which 1096 (11.1%) were maternal deaths. Based on 2004–2006 SRS national MMR estimates of 254 deaths per 100 000 live births, we estimated rural areas of poorer states had the highest MMR (397, 95%CI 385–410) compared to the lowest MMR in urban areas of richer states (115, 95%CI 85–146). We estimated 69 400 maternal deaths in India in 2005. Three-quarters of maternal deaths were clustered in rural areas of poorer states, although these regions have only half the estimated live births in India. Most maternal deaths were attributed to direct obstetric causes (82%). There was no difference in the major causes of maternal deaths between poorer and richer states. Two-thirds of women died seeking some form of healthcare, most seeking care in a critical medical condition. Rural areas of poorer states had proportionately lower access and utilization to healthcare services than the urban areas; however this rural-urban difference was not seen in richer states.Conclusions
Maternal mortality and poor access to healthcare is disproportionately higher in rural populations of the poorer states of India. 相似文献44.
Russell G. Death 《Oikos》2002,97(1):18-30
The link between substrate disturbance and stream invertebrate species richness is often complicated by the fact that substrate disturbance removes both invertebrates and periphyton (a potential food source). It is never clear whether disturbance acts directly on species diversity by removing animals or indirectly by reducing one of their food sources. To examine this relationship invertebrate diversity patterns were examined in 25 forest streams in Urewera National Park, New Zealand, where light attenuation from the forest canopy was postulated to limit periphyton biomass and remove the confounding influence of periphyton on the link between substrate disturbance and invertebrate diversity. Invertebrate species richness declined linearly with increasing substrate disturbance. Although periphyton biomass was comparatively low, species richness was more strongly related to periphyton biomass than to any disturbance measure. The highly mobile nature and terrestrial reproductive stage of many lotic invertebrates suggest that colonisation dynamics may have a more important influence on diversity patterns than monopolisation of resources for population growth. Although both the intermediate disturbance hypothesis and the dynamic equilibrium model encompass colonisation as a critical determinant of diversity both models also require a trade-off between the colonising and competitive ability of individual species; a phenomenon which does not appear to occur widely in lotic communities. Rather, it is postulated that resource levels will set an upper limit to the species richness of a benthic community that can be achieved through colonisation of taxa in the absence of disturbance, while disturbance removes taxa and resets the colonisation process. 相似文献
45.
Anti-convulsant treatment is associated with a high prevalence of reproductive dysfunction compared with age-matched non-epileptics. We examined the widely used anti-convulsants valproate (VPA) and carbamazepine (CBZ) for steroidal bioactivity using a yeast-based steroid receptor-beta-galactosidase reporter assay for the androgen receptor (AR), progesterone receptor (PR) or estrogen receptor (ER). Bioassays were performed (a) to detect agonist activity by exposing yeast to 100 microM CBZ or VPA or (b) to detect antagonist activity by exposing yeast stimulated with testosterone (5 x 10(-9) M, AR), progesterone (1.6 x 10(-9) M, PR) or estradiol (2.6 x 10(-11) M, ER) together with either VPA or CBZ for 4 (PR) or 16 (AR, ER) hours. VPA showed dose-dependent (1-800 microM) inhibition of progesterone-induced PR- and testosterone-induced AR activity but had no ER antagonist bioactivity and no significant PR, AR or ER agonist bioactivity. VPA also showed a dose-dependent (1-200 microM) blockade of DHT's suppression of AR-mediated NF-kappaB activation in human mammalian cells. By contrast, CBZ had no significant PR, AR or ER agonist or AR and ER antagonist bioactivity but at the highest concentration tested (800 microM) it did antagonize PR activity. We conclude that VPA is a non-steroidal antagonist for human AR and PR but not ER. VPA's androgen and progesterone antagonism at concentrations within therapeutic blood levels (350-700 microM) seems likely to contribute to the frequency of reproductive endocrine disturbances among patients treated with VPA. 相似文献
46.
The taste of polycose in hamsters 总被引:2,自引:2,他引:0
Hamsters show a preference for Polycose, a mixture of starch-derived
glucose polymers, that is as strong as their preference for sucrose.
However, in the hamster, taste aversions to Polycose may be less easily
acquired than taste aversions to sucrose and the qualitative aspects of
Polycose are unknown in this species. In order to examine the taste of
Polycose in the hamster, we utilized a taste-aversion protocol with two
conditioning trials. Animals were trained to avoid one of three different
conditioning stimuli: 50 mM sucrose, 100 mM Polycose and a mixture of 50 mM
sucrose with 100 mM Polycose. Control animals were conditioned with
deionized water. After the second conditioning trial, generalization
testing began for the three conditioning stimuli plus 3 mM citric acid, 300
mM KCI and 30 mM NaCl. The results showed that aversions to Polycose,
sucrose or the Polycose/sucrose mixture cross- generalized, demonstrating
that Polycose and sucrose share a common taste percept in the hamster. None
of the aversions generalized to NaCl, citric acid or KCI. In addition,
comparisons among the patterns of taste generalizations indicated that the
tastes of Polycose and sucrose also had distinct qualitative components.
Finally, although the taste of 100 mM Polycose was more salient than the
taste of 50 mM sucrose, the taste of sucrose could still be detected in a
mixture with Polycose.
相似文献
47.
Purification of galectin-3 from ovine placenta: developmentally regulated expression and immunological relevance 总被引:1,自引:1,他引:1
Iglesias MM; Rabinovich GA; Ambrosio AL; Castagna LF; Sotomayor CE; Wolfenstein-Todel C 《Glycobiology》1998,8(1):59-65
Galectins, beta-galactoside-binding lectins, are extensively distributed in
the animal kingdom and share some basic molecular properties. Galectin-3, a
member of this family, is generally associated with differentiation,
morphogenesis, and metastasis. In this study, galectin-3 was isolated from
ovine placental cotyledons round the middle of the gestation period by
lactose extraction followed by affinity chromatography on lactosyl-agarose,
and separated from galectin-1 by size exclusion chromatography on a
Superose 12 column. Under native conditions this lectin behaved as a
monomer with an apparent molecular weight of approximately 29,000 and an
isoelectric point of 9.0. The partial amino acid sequence of the peptides
obtained by tryptic digestion of this protein followed by HPLC separation
showed striking homology with other members of the galectin-3 subfamily.
Furthermore, ovine placental galectin-3 exhibited specific mitogenic
activity toward rat spleen mononuclear cells. Besides, this protein
strongly reacted with a rabbit antiserum raised against a chicken galectin.
Results obtained by Western blot analysis showed that its expression was
greatly decreased in term placenta with respect to the middle of the
gestation period, suggesting a regulated expression throughout development.
相似文献
48.
Russell G. Death 《Hydrobiologia》2004,513(1-3):171-182
Spatial resource overlap by benthic invertebrates was investigated between stones in 11 freshwater habitats (10 streams and a wind-swept lake shore) of similar physicochemical nature but different thermal and hydrologic stability in the Cass-Craigieburn region, New Zealand. Both overlap and breadth of stone use by the invertebrate taxa decreased as stability declined, in part because of the lower number of species available with which to share resources at unstable sites. Although there was no evidence for resource partitioning of stones, communities at stable sites and on more stable substrates differed from those that would have been expected to accumulate by chance colonisation alone. Stone assemblages at unstable sites are dominated by the same general suite of species well suited to surviving disturbances, while conditions at stable sites allow more specialised taxa to colonise individual stones differentially. 相似文献
49.
Marjolijn CE Bragt Jogchum Plat Marco Mensink Patrick Schrauwen Ronald P Mensink 《BMC endocrine disorders》2009,9(1):1-9
Background
The aim of this study is to perform a cost-effectiveness comparison between palpation-guided thyroid fine-needle aspiration biopsies (P-FNA) and ultrasound-guided thyroid FNA biopsies (USG-FNA).Methods
Each nodule was considered as a case. Diagnostic steps were history and physical examination, TSH measurement, Tc99m thyroid scintigraphy for nodules with a low TSH level, initial P-FNA versus initial USG-FNA, repeat USG-FNA for nodules with initial inadequate P-FNA or USG-FNA, hemithyroidectomy for inadequate repeat USG-FNA. American Thyroid Association thyroid nodule management guidelines were simulated in estimating the cost of P-FNA strategy. American Association of Clinical Endocrinologists guidelines were simulated for USG-FNA strategy. Total costs were estimated by adding the cost of each diagnostic step to reach a diagnosis for 100 nodules. Strategy cost was found by dividing the total cost to 100. Incremental cost-effectiveness ratio (ICER) was calculated by dividing the difference between strategy cost of USG-FNA and P-FNA to the difference between accuracy of USG-FNA and P-FNA. A positive ICER indicates more and a negative ICER indicates less expense to achieve one more additional accurate diagnosis of thyroid cancer for USG-FNA.Results
Seventy-eight P-FNAs and 190 USG-FNAs were performed between April 2003 and May 2008. There were no differences in age, gender, thyroid function, frequency of multinodular goiter, nodule location and diameter (median nodule diameter: 18.4 mm in P-FNA and 17.0 mm in USG-FNA) between groups. Cytology results in P-FNA versus USG-FNA groups were as follows: benign 49% versus 62% (p = 0.04), inadequate 42% versus 29% (p = 0.03), malignant 3% (p = 1.00) and indeterminate 6% (p = 0.78) for both. Eleven nodules from P-FNA and 18 from USG-FNA group underwent surgery. The accuracy of P-FNA was 0.64 and USG-FNA 0.72. Unit cost of P-FNA was 148 Euros and USG-FNA 226 Euros. The cost of P-FNA strategy was 534 Euros and USG-FNA strategy 523 Euros. Strategy cost includes the expense of repeat USG-FNA for initial inadequate FNAs and surgery for repeat inadequate USG-FNAs. ICER was -138 Euros.Conclusion
Universal application of USG-FNA for all thyroid nodules is cost-effective and saves 138 Euros per additional accurate diagnosis of benign versus malignant thyroid nodular disease.Trial registration
ClinicalTrials.gov, NCT00571090 相似文献50.
Interaction between disturbance and primary productivity in determining stream invertebrate diversity 总被引:2,自引:0,他引:2
Invertebrate diversity patterns were examined in 10 streams that differed in substrate disturbance rates, in Taranaki, New Zealand, between April 1999 and January 2000. Two sites on each stream were sampled, one under native forest canopy where light was postulated to limit periphyton growth and a similar site 225–3800 m downstream in open grassland. Periphyton biomass was considerably higher at open stable sites than at closed or unstable sites. Associated with the higher algal biomass, species number and total abundance of animals were higher at open canopy sites. Species number exhibited a negative linear relationship with disturbance but only at open sites. In contrast, rarefied species richness exhibited a negative linear relationship with disturbance at both open and closed sites. This was a result of communities at the more disturbed sites being numerically dominated by only a few taxa compared to the more evenly distributed communities at stable sites. The observed patterns provide little support for contemporary diversity disturbance models but suggest diversity of invertebrates in streams is a function of time since the last disturbance, mediated through recovery of the food base in autotrophic streams. 相似文献