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241.
The breeding biology and cone size selection of crossbills was studied mainly during 1995 to 2002 at Abernethy Forest, Scotland, an ancient native Scots pine Pinus sylvestris wood, where only a single crossbill species, the Scottish crossbill Loxia scotica, was assumed to occur and to be adapted to feed on seeds in Scots pine cones. However, three crossbill species (common Loxia curvirostra, Scottish and parrot crossbills Loxia pytyopsittacus) nested in some years, with the parrot crossbill being the most abundant. Most nests were in old large pines, with the three crossbill species not differing in their use of tree size or stand density for nesting. The mean clutch and brood sizes were 3.8 and 2.9, and their mean survivals were 86 and 74%, respectively, with no significant differences among species. The timing of breeding differed between species, with parrot crossbills breeding earliest (median date 21 March, including second attempts) and common crossbills breeding last (median date 21 April), probably in response to the differing accessibility of Scots pine seeds to these species. The difference in the time of breeding may reduce mixed mating. Crossbills foraged preferentially on trees with small cones when the cones were closed. Small cones had thinner scales than large cones, suggesting that the preference for small cones was related to higher feeding rates on these cones when cones are closed. Such a preference was also found for captive crossbills with the Scottish crossbill showing a more pronounced preference for smaller cones than the larger‐billed parrot crossbill. However, crossbills selected larger cones within trees and trees with larger cones once the cones opened in April. Such a shift occurred presumably because variation in scale thickness has little impact on seed accessibility once cones open, and larger cones have larger and more seeds. The greater ability of parrot crossbills to exploit seeds in closed Scots pine cones allowed parrot crossbills to start breeding earlier and to have young when seeds were most accessible. Only after the cones opened were the smaller‐billed common crossbills able to easily access seeds and to start breeding. The time of breeding of Scottish crossbills was intermediate between common and parrot crossbills, and they probably had an intermediate ability to exploit Scots pine cones. The reason why there were few Scottish crossbills nesting in Abernethy Forest remains a puzzle, considering that native pine wood is assumed to be the ancestral habitat to which the Scottish crossbill is adapted. The breeding season for all crossbills ended in June, when most of the seed from a given cone cohort was shed. This is when starved broods were found, not associated with bad weather. 相似文献
242.
Indicators for biodiversity and ecosystem services: towards an improved framework for ecosystems assessment 总被引:1,自引:0,他引:1
Christian K. Feld José Paulo Sousa Pedro Martins da Silva Terence P. Dawson 《Biodiversity and Conservation》2010,19(10):2895-2919
Ecosystem assessment and monitoring requires the development and application of suitable indicators, i.e. they need to be
(i) reliable and capable of simplifying complex relationships, (ii) quantifiable and transparent in order to enable an easy
communication, and (iii) fit for the purpose of indication. These requirements are scarcely fulfilled in current ecosystem
assessment and monitoring efforts to address the requirements of international biodiversity conventions. Here we present and
test a set of seven criteria towards an improved framework for ecosystems indication with particular emphasis on the indication
of biodiversity and ecosystem services: purpose of indication, indicator type according to the EEA’s Driver-Pressure-State-Impact-Response
scheme, direct/indirect linkages to biodiversity and ecosystem services, spatial scale and scalability across scales, applicability
of benchmarks/reference values, availability of data and protocols, and applicability of remote sensing. The criteria are
tested using 24 indicators of ecosystem assessment and monitoring at the global, continental and regional scale. Based on
the general trends revealed by our evaluation, we present recommendations to streamline and improve ecosystem indication with
respect to international biodiversity conventions. The implementation of our recommendations does require concerted international
effort, comparable, for instance, to the implementation of the Water Framework Directive in Europe. 相似文献
243.
Laszlo Revesz Achim Schlapbach Reiner Aichholz Janet Dawson Roland Feifel Stuart Hawtin Amanda Littlewood-Evans Guido Koch Markus Kroemer Henrik Möbitz Clemens Scheufler Juraj Velcicky Christine Huppertz 《Bioorganic & medicinal chemistry letters》2010,20(15):4719-4723
Spirocyclopropane- and spiroazetidine-substituted tetracycles 13D–E and 16A are described as orally active MK2 inhibitors. The spiroazetidine derivatives are potent MK2 inhibitors with IC50 <3 nM and inhibit the release of TNFα (IC50<0.3 μM) from hPBMCs and hsp27 phosphorylation in anisomycin stimulated THP-1 cells. The spirocyclopropane analogues are less potent against MK2 (IC50 = 0.05–0.23 μM), less potent in cells (IC50 <1.1 μM), but show good oral absorption. Compound 13E (100 mg/kg po; bid) showed oral activity in rAIA and mCIA, with significant reduction of swelling and histological score. 相似文献
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246.
Natural selection theory suggests that there should be fitness consequences for animals that possess morphological abnormalities such as missing or deformed appendages and other structures. As these characters are expected to be detrimental, morphological abnormalities could be considered “handicaps”. However, little information exists about the nature, prevalence or consequences of naturally occurring handicaps in birds, even though experimental handicapping has been used in some behavioural studies. Here, we document and describe the frequency of natural handicaps in American Kestrels Falco sparverius, and investigate their influence on condition and survival. We considered three different categories of handicap that should negatively impact falcons: missing remiges and rectrices, broken remiges and rectrices, and foot handicaps. Broken feathers, followed by missing feathers, were the most common handicaps detected in kestrels and their prevalence increased throughout the breeding season. Foot handicaps were relatively rare and showed no seasonal trends. There was no effect of any handicap type on body condition or return rates of male kestrels. In contrast, females with either foot handicaps or broken feathers were in significantly poorer condition than control females, and females with broken feathers were less likely than control females to return to the study area in years following initial capture. Given that female kestrels with broken feathers have more fault bars than those without broken feathers, and fault bar formation is related to stresses in a bird's past, we suggest that female kestrels that had broken feathers were of poorer quality than those without broken feathers or those with missing feathers. Females with broken feathers may therefore have been in poorer condition initially than other birds, or if broken feathers are indicative of poor quality, then females with broken feathers may have been less able to cope with the negative impacts of feather loss on flight performance compared to birds with missing feathers. 相似文献
247.
Stephen M. Dawson 《Ethology : formerly Zeitschrift fur Tierpsychologie》1991,88(4):265-276
Hector's dolphins (Cephalorhynchus hectori) have a simple vocal repertoire, consisting almost entirely of ultrasonic clicks. They produce no whistles, and very few audible sounds. To examine acoustic communication in this species I analysed the relationship between click types and behaviour. The proportion of complex click types was greater in large groups, suggesting that these sounds have social significance. Clicks having 2 peaks in their time envelope and two frequency peaks were strongly associated with behaviours indicative of feeding. High pulse rate sounds, in which the repetition rate of ultrasonic clicks was audible as a “cry”, were most strongly associated with aerial behaviours. These data suggest that echo-location is not the sole function of Hector's dolphin clicks, and that echo-location and communication are likely to be closely linked. I hypothesize that dolphins may have the ability to gather information from the echoes of each other's sonar pulses. This may reduce the need for a large number of vocal signals, and may explain the apparent simplicity of the acoustic repertoires of some odontocetes. 相似文献
248.
A simple population genetic model is presented for a hermaphrodite annual species, allowing both selfing and outcrossing. Those male gametes (pollen) responsible for outcrossing are assumed to disperse much further than seeds. Under this model, the pedigree of a sample from a single locality is loop-free. A novel Markov chain Monte Carlo strategy is presented for sampling from the joint posterior distribution of the pedigree of such a sample and the parameters of the population genetic model (including the selfing rate) given the genotypes of the sampled individuals at unlinked marker loci. The computational costs of this Markov chain Monte Carlo strategy scale well with the number of individuals in the sample, and the number of marker loci, but increase exponentially with the age (time since colonisation from the source population) of the local population. Consequently, this strategy is particularly suited to situations where the sample has been collected from a population which is the result of a recent colonisation process. 相似文献
249.
An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10 下载免费PDF全文
Nelson JD Brunel FM Jensen R Crooks ET Cardoso RM Wang M Hessell A Wilson IA Binley JM Dawson PE Burton DR Zwick MB 《Journal of virology》2007,81(8):4033-4043
The membrane-proximal external region (MPER) of human immunodeficiency virus type 1 (HIV-1) gp41 bears the epitopes of two broadly neutralizing antibodies (Abs), 2F5 and 4E10, making it a target for vaccine design. A third Ab, Fab Z13, had previously been mapped to an epitope that overlaps those of 2F5 and 4E10 but only weakly neutralizes a limited set of primary isolates. Here, libraries of Fab Z13 variants displayed on phage were engineered and affinity selected against an MPER peptide and recombinant gp41. A high-affinity variant, designated Z13e1, was isolated and found to be approximately 100-fold improved over the parental Fab not only in binding affinity for the MPER antigens but also in neutralization potency against sensitive HIV-1. Alanine scanning of MPER residues 664 to 680 revealed that N671 and D674 are crucial for peptide recognition as well as for the neutralization of HIV-1 by Z13e1. Ab competition studies and truncation of MPER peptides indicate that Z13e1 binds with high affinity to an epitope between and overlapping with those of 2F5 and 4E10, with the minimal peptide epitope WASLWNWFDITN. Still, Z13e1 remained about an order of magnitude less potent than 4E10 against several isolates of pseudotyped HIV-1. The sum of our molecular analyses with Z13e1 suggests that the segment on the MPER of gp41 between the 2F5 and 4E10 epitopes is exposed on the functional envelope trimer but that access to the specific Z13e1 epitope within this segment is limited. Thus, the ability of MPER-bearing immunogens to elicit potent HIV-1-neutralizing Abs may depend in part on recapitulating the particular constraints that the functional envelope trimer imposes on the segment of the MPER to which Z13e1 binds. 相似文献
250.
Andrew J. Dugmore Douglas M. Borthwick Mike J. Church Alastair Dawson Kevin J. Edwards Christian Keller Paul Mayewski Thomas H. McGovern Kerry-Anne Mairs Guðrún Sveinbjarnardóttir 《Human ecology: an interdisciplinary journal》2007,35(2):169-178
In order to assess possible contributions of climate change to the human ecology of the North Atlantic islands we evaluate
the utility of cumulative deviations from the mean, calculated for the Greenland ice core storm frequency proxy (GISP2 Na+) and sea ice proxy (GISP2 chloride excess). Our aim is to identify episodes of unpredictable change in the context of long-term
trends of cultural and environmental development. Key changes are identified in the proxy climate records in 975 and 980 ad, 1025 and 1040 ad, 1180 ad, 1425 and 1450 ad, and 1520 and 1525 ad. Some of these changes are consistent with those inferred from new studies of the palaeoecological record of the Faroes.
This indicates that the cumulative deviation measure could give greatest prominence to the most important climate changes
affecting landscapes and settlement (such as the changes of 1425 and 1450 ad and their immediate aftermath), rather than extreme events, such as great single storms. 相似文献