Application of Genome-Wide Expression Analysis To Identify Molecular Markers Useful in Monitoring Industrial Fermentations

Genome-wide expression analysis of an industrial strain of Saccharomyces cerevisiae identified the YOR387c and YGL258w homologues as highly inducible in zinc-depleted conditions. Induction was specific for zinc deficiency and was dependent on Zap1p. The results indicate that these sequences may be valuable molecular markers for detecting zinc deficiency in industrial fermentations.     

The association between cardiac accelerations and movements in fetal sheep

Observations in 5 fetal sheep at 120-134 days gestation, using either real time ultrasound or direct emg recordings to detect fetal movements, showed an association between such movements and cardiac accelerations (greater than 2 s duration and 4 beats/min amplitude). Neuromuscular blockade with gallamine abolished the fetal movements but not the accelerations.