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Gracia-Marco L Valtueña J Ortega FB Pérez-López FR Vicente-Rodríguez G Breidenassel C Ferrari M Molnar D Widhalm K de Henauw S Kafatos A Diaz LE Gottrand F Maiani G Stehle P Castillo MJ Moreno LA González-Gross M;on behalf of the HELENA Study Group 《Journal of applied physiology (Bethesda, Md. : 1985)》2012,113(4):566-573
There is a lack of studies that analyze the association between micronutrient-related biomarker status and physical fitness in adolescents. In the present study, biochemical parameters for iron and vitamin status were studied, along with objective measures of physical fitness in healthy male and female European adolescents. One thousand eighty-nine adolescents (580 girls, 12.5-17.5 yr) from the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) cross-sectional study were included. Hierarchical linear models were performed to determine the associations between micronutrient biomarkers and physical fitness. Age, seasonality, latitude, body mass index, menarche (in girls), and physical activity were used as covariates. For cardiorespiratory fitness, concentrations of hemoglobin, retinol, and vitamin C in male adolescents and β-carotene and 25(OH)D in female adolescents were associated with maximal oxygen consumption. For muscular fitness, concentrations of hemoglobin, β-carotene, retinol, and α-tocopherol in male adolescents and β-carotene and 25(OH)D in female adolescents were associated with better performance of the standing long jump test. In summary, concentrations of hemoglobin and most antioxidant vitamins in male adolescents and β-carotene and 25(OH)D in female adolescents were positively associated with cardiorespiratory and muscular fitness, after controlling for relevant confounders. The associations between physical fitness and iron or vitamin status observed in this cross-sectional study in adolescents should be followed up by a study specifically designed to evaluate causal relationships. 相似文献
154.
The formation of titan cells in Cryptococcus neoformans depends on the mouse strain and correlates with induction of Th2‐type responses 下载免费PDF全文
Irene García‐Barbazán Nuria Trevijano‐Contador Cristina Rueda Belén de Andrés Raquel Pérez‐Tavárez Inés Herrero‐Fernández María Luisa Gaspar Oscar Zaragoza 《Cellular microbiology》2016,18(1):111-124
Cryptococcus neoformans is a pathogenic yeast that can form titan cells in the lungs, which are fungal cells of abnormal enlarged size. Little is known about the factors that trigger titan cells. In particular, it is not known how the host environment influences this transition. In this work, we describe the formation of titan cells in two mouse strains, CD1 and C57BL/6J. We found that the proportion of C. neoformans titan cells was significantly higher in C57BL/6J mice than in CD1. This higher proportion of titan cells was associated with a higher dissemination of the yeasts to the brain. Histology sections demonstrated eosinophilia in infected animals, although it was significantly lower in the CD1 mice which presented infiltration of lymphocytes. Both mouse strains presented infiltration of granulocytes, but the amount of eosinophils was higher in C57BL/6J. CD1 mice showed a significant accumulation of IFN‐γ, TNF‐α and IL17, while C57BL/BL mice had an increase in the anti‐inflammatory cytokine IL‐4. IgM antibodies to the polysaccharide capsule and total IgE were more abundant in the sera from C57BL/6J, confirming that these animals present a Th2‐type response. We conclude that titan cell formation in C. neoformans depends, not only on microbe factors, but also on the host environment. 相似文献
155.
María Capa Pat Hutchings M. Teresa Aguado Nathan J. Bott 《Cladistics : the international journal of the Willi Hennig Society》2011,27(5):449-469
The monophyly of Sabellidae, the phylogenetic relationships of its lineages, and the composition of Sabellida have been debated for many decades. Most studies on sabellid phylogeny have focused on morphological features but little DNA work has been published to date. We performed analyses using maximum‐parsimony methods that included 36 sabellids and members of previously related taxa. We integrated morphological and DNA sequence data to resolve relationships at different hierarchical levels (135 morphological features, fragments of the nuclear ribosomal RNA genes 18S and 28S, and the mitochondrial gene 16S). The results indicate the monophyly of Sabellida, including Sabellidae and Serpulidae. Monophyly of Fabriciinae and Serpulidae is assessed and the two groups are recovered as sister taxa, but with weak support. There is no significant support for the monophyly of Sabellinae. Relationships between members of the Sabellidae are still partially unresolved due to incongruence between partitions and low support for most clades. The evolution and transformation of certain characters within Sabellidae is explored.© The Willi Hennig Society 2010. 相似文献
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Javier Mar Arantzazu Arrospide José María Begiristain Isabel Larrañaga Elena Elosegui Juan Oliva-Moreno 《BMC neurology》2011,11(1):46
Background
Patients with acquired brain damage (ABD) have suffered a brain lesion that interrupts vital development in the physical, psychological and social spheres. Stroke and traumatic brain injury (TBI) are the two main causes. The objectives of this study were to estimate the incidence and prevalence of ABD in the population of the Basque Country and Navarre in 2008, to calculate the associated cost of the care required and finally to assess the loss in health-related quality of life. 相似文献158.
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Carlos Rico José Luis Rico Noelia Muñoz Beatriz Gómez Iñaki Tejero 《Engineering in Life Science》2011,11(5):476-481
The effect of mixing on biogas production of a 1.5‐m3 pilot continuous stirred tank reactor (CSTR) processing screened dairy manure was evaluated. Mixing was carried out by recirculation of reactor content with a mono pump. The experiment was conducted at a controlled temperature of 37±1°C and hydraulic retention times (HRTs) of 20 and 10 days. The effect of continuous and intermittent operation of the recirculation pump on biogas production was studied. At 10 days of HRT, the results showed a minimal influence of recirculation rate on biogas production and that continuous recirculation did not improve reactor performance. At 20 days of HRT, the recirculation rate did not affect reactor performance. Combination of low solid content in feed animal slurry and long HRTs results in minimal mixing requirements for anaerobic digestion. 相似文献