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991.
992.
Carlos Eduardo Aucique‐Prez Renata Sousa Resende Lara Beatriz Cruz Neto Fernanda Dornelas Fbio Murilo DaMatta Fabrício vila Rodrigues 《Physiologia plantarum》2019,167(4):628-644
Fungal pathogens produce toxins that are important for their pathogenesis and/or aggressiveness towards their hosts. Picolinic acid (PA), a non‐host selective toxin, causes lesions on rice leaves resembling those originated from Pyricularia oryzae infection. Considering that non‐host selective toxins can be useful for plant diseases control, this study investigated whether the foliar spray with PA on wheat (Triticum aestivum L.) plants, in a non‐phytotoxic concentration, could increase their resistance to blast, stimulate the anti‐oxidative metabolism, and minimize alterations in photosynthesis. The PA spray at concentrations greater than 0.1 mg ml?1 caused foliar lesions, compromised the photosynthesis and was linked with greater accumulation of hydrogen peroxide (H2O2) and superoxide anion radical (O2??). Fungal mycelial growth, conidia production and germination decreased by PA at 0.3 mg ml?1. Blast severity was significantly reduced by 59 and 23%, respectively, at 72 and 96 h after inoculation for plants sprayed with PA (0.1 mg ml?1) at 24 h before fungal inoculation compared to non‐sprayed plants. Reduction on blast symptoms was linked with increases on ascorbate peroxidase (EC 1.11.1.11), catalase (EC 1.11.1.6), glutathione peroxidase (EC 1.11.1.9), glutathione reductase (EC 1.8.1.7), glutathione‐S‐transferase (EC 2.5.1.18), peroxidase (EC 1.11.1.7), and superoxide dismutase (EC 1.15.1.1) activities, lower H2O2 and O2?? accumulation, reduced malondialdehyde production as well as less impairments to the photosynthetic apparatus. A more efficient antioxidative metabolism that rapidly scavenges the reactive oxygen species generated during P. oryzae infection, without dramatically decreasing the photosynthetic performance, was a remarkable effect obtained with PA spray. 相似文献
993.
994.
Uriel Hernndez‐Salinas Aurelio Ramírez‐Bautista Raciel Cruz‐Elizalde Shai Meiri Christian Berriozabal‐Islas 《Ecology and evolution》2019,9(4):2061-2071
Juvenile growth rates are thought to be restricted by available food resources. In animals that grow throughout the year, such as tropical lizards, growth is therefore predicted to be faster during the rainy season. We test this prediction using a population of Anolis nebulosusby describing the growth trajectories of both sexes using nonlinear regression models, and we then correlate the growth rates of individuals with food available in the environment, precipitation, and temperature. The Von Bertalanffy model fits the growth rates of the females better, while the logistic‐by‐length model fits the males better. According to both models, the males grew faster than females, reaching slightly smaller sizes at adulthood. Males reached sexual maturity when 35 mm long, at an age of seven months, and females matured at 37 mm (SVL), taking nine months to reach this size. In 1989, juvenile males and females grew more in both seasons (rainy and dry) than adults; for 1990, there were no differences by season or between age classes. These results are interesting since in the 1989 and 1990 rainy seasons, practically the same orders of prey and the greatest abundance of prey available in the environment were registered. A possible explanation could be that predation was more intense in 1990 than in 1989. There is little evidence that food, temperature, and humidity affect growth rates of A. nebulosus, refuting our predictions. This is mainly due to the low variation in growth observed in 1990. Therefore we think that the growth of this species reflects a complex combination of ecological and genetic factors. 相似文献
995.
Patricia Ana Vic H. Arcega Chiara Louise P. Cabantac Ronald Allan L. Cruz 《Developing world bioethics》2019,19(3):180-185
Research involving human participants has been conducted in the Philippines since the beginning of the Spanish colonial period. Such studies are expected to adhere to internationally accepted ethical guidelines. This paper discusses trends in clinical research ethics in the Philippines during the American colonial period (1898‐1946). Specifically, studies were assessed on: 1) their observance of ethical protocols, including review; 2) identification of inclusion and exclusion criteria in the selection of participants; 3) use of vulnerable subjects; and 4) practice of the informed consent process. Only the informed consent process had a significant logistic correlation with progression of years. Recruitment of vulnerable groups was common during this period; children and prisoners were the most common participants. Trends in medical ethics in the Philippines reflected those in the United States prior to the publication of the Nuremberg Code, which served as a milestone in the protection of human welfare in clinical research. 相似文献
996.
Daniela G Morato Florisneide R Barreto José U Braga Marcio S Natividade Maria da Concei??o N Costa Vanessa Morato Maria da Glória Lima Cruz Teixeira 《Memórias do Instituto Oswaldo Cruz》2015,110(4):528-533
Understanding the transmission dynamics of infectious diseases is important to allow
for improvements of control measures. To investigate the spatiotemporal pattern of an
epidemic dengue occurred at a medium-sized city in the Northeast Region of Brazil in
2009, we conducted an ecological study of the notified dengue cases georeferenced
according to epidemiological week (EW) and home address. Kernel density estimation
and space-time interaction were analysed using the Knox method. The evolution of the
epidemic was analysed using an animated projection technique. The dengue incidence
was 6.918.7/100,000 inhabitants; the peak of the epidemic occurred from 8 February-1
March, EWs 6-9 (828.7/100,000 inhabitants). There were cases throughout the city and
was identified space-time interaction. Three epicenters were responsible for
spreading the disease in an expansion and relocation diffusion pattern. If the health
services could detect in real time the epicenters and apply nimbly control measures,
may possibly reduce the magnitude of dengue epidemics. 相似文献
997.
Oswaldo Cruz‐Neto Isabel C. Machado Leonardo Galetto Ariadna V. Lopes 《Botanical journal of the Linnean Society. Linnean Society of London》2015,177(2):230-245
Floral morphology, nectar secretion strategies and the contribution of pollinators to the reproductive success of plants provide important clues regarding the levels of generalization or specialization in pollination systems. Anthesis throughout the day and night allows flowers to be visited by diurnal and nocturnal pollinators, promoting generalization or specialization. We studied three species in the diverse tropical genus Inga to: (1) quantify the response of flowers to successive nectar extractions and (2) determine the contribution of diurnal and nocturnal floral visitors to female reproductive success. Inga flowers could be clearly distinguished mainly on the basis of the staminal tube diameter and the quantities of filaments and pollen grains. Successive nectar removals led to a decrease of 60% in the total nectar secretion in I. vera and to increases of 20% in I. ingoides and 10% in I. striata. Despite these differences, the studied Inga spp. exhibited similar patterns of visitation rates and shared diurnal and nocturnal pollinators. Nocturnal pollinators contributed ten times more than diurnal pollinators to the female reproductive success of Inga. Floral morphology, nectar secretion patterns and pollination ecology data suggest an evolutionary trend towards specialization for nocturnal pollinators in Inga spp. with crepuscular or nocturnal flowers. © 2014 The Linnean Society of London, Botanical Journal of the Linnean Society, 2015, 177 , 230–245. 相似文献
998.
Hercules Antônio da Silva-Souza Maria Nathalia de Lira Helio Miranda Costa-Junior Cristiane Monteiro da Cruz Jorge Silvio Silva Vasconcellos Anderson Nogueira Mendes Gabriela Pimenta-Reis Cora Lilia Alvarez Lucia Helena Faccioli Carlos Henrique Serezani Julieta Schachter Pedro Muanis Persechini 《生物化学与生物物理学报:生物膜》2014
We have previously described that arachidonic acid (AA)-5-lipoxygenase (5-LO) metabolism inhibitors such as NDGA and MK886, inhibit cell death by apoptosis, but not by necrosis, induced by extracellular ATP (ATPe) binding to P2X7 receptors in macrophages. ATPe binding to P2X7 also induces large cationic and anionic organic molecules uptake in these cells, a process that involves at least two distinct transport mechanisms: one for cations and another for anions. Here we show that inhibitors of the AA-5-LO pathway do not inhibit P2X7 receptors, as judged by the maintenance of the ATPe-induced uptake of fluorescent anionic dyes. In addition, we describe two new transport phenomena induced by these inhibitors in macrophages: a cation-selective uptake of fluorescent dyes and the release of ATP. The cation uptake requires secreted ATPe, but, differently from the P2X7/ATPe-induced phenomena, it is also present in macrophages derived from mice deficient in the P2X7 gene. Inhibitors of phospholipase A2 and of the AA-cyclooxygenase pathway did not induce the cation uptake. The uptake of non-organic cations was investigated by measuring the free intracellular Ca2 + concentration ([Ca2 +]i) by Fura-2 fluorescence. NDGA, but not MK886, induced an increase in [Ca2 +]i. Chelating Ca2 + ions in the extracellular medium suppressed the intracellular Ca2 + signal without interfering in the uptake of cationic dyes. We conclude that inhibitors of the AA-5-LO pathway do not block P2X7 receptors, trigger the release of ATP, and induce an ATP-dependent uptake of organic cations by a Ca2 +- and P2X7-independent transport mechanism in macrophages. 相似文献
999.
1000.
Randia lorenceana (Rubiaceae), a new species from the cloud forest in the state of Guerrero, Mexico, is described and illustrated. The new species is related to R. matudae, but it differs from that species in having larger stipules, peduncles and calyx lobes, smaller corolla lobes, anthers, and hypanthium in the staminate flowers, and distinctly pendulous fruits due the of the bending of the peduncles. 相似文献